acompound

Showing entry for Cochinchinone A

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0029684
Compound Name	Cochinchinone A
Structure
Formula	C28H32O5
InchiKey	ZHJQVNDLFGICFY-VCHYOVAHSA-N
SMILES	C/C(=C\Cc1c(O)c(CC=C(C)C)c(c2c1oc1ccc(cc1c2=O)O)O)/CCC=C(C)C
Inchi	InChI=1S/C28H32O5/c1-16(2)7-6-8-18(5)10-13-21-25(30)20(12-9-17(3)4)26(31)24-27(32)22-15-19(29)11-14-23(22)33-28(21)24/h7,9-11,14-15,29-31H,6,8,12-13H2,1-5H3/b18-10+
IUPAC	4-[(2E)-3,7-dimethylocta-2,6-dienyl]-1,3,7-trihydroxy-2-(3-methylbut-2-enyl)xanthen-9-one
Molecular Weight	448.22
Pubchem Id	11633740
Chembl Id	CHEMBL1782241

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT012754	Transcription factor p65	reviewed	Transcription factor	RELA	-	>10000	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q04206	BXGT012754	Transcription factor p65	reviewed	Transcription factor	RELA	IC50	'>'	10000	nM
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	IC50	'='	5200	nM
Q2M2H8	BXGT026100	Probable maltase-glucoamylase 2	reviewed	Enzyme	MGAM2	Inhibition	-	-	-
P14410	BXGT008009	Sucrase-isomaltase, intestinal	reviewed	Enzyme	SI	Inhibition	-	-	-
P10253	BXGT007550	Lysosomal alpha-glucosidase	reviewed	Enzyme	GAA	Inhibition	-	-	-
O43451	BXGT004594	Maltase-glucoamylase, intestinal	reviewed	Enzyme	MGAM	Inhibition	-	-	-
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	Inhibition	-	-	-
Q2M2H8	BXGT026100	Probable maltase-glucoamylase 2	reviewed	Enzyme	MGAM2	Ki	'='	13400	nM
P14410	BXGT008009	Sucrase-isomaltase, intestinal	reviewed	Enzyme	SI	Ki	'='	13400	nM
P10253	BXGT007550	Lysosomal alpha-glucosidase	reviewed	Enzyme	GAA	Ki	'='	13400	nM
O43451	BXGT004594	Maltase-glucoamylase, intestinal	reviewed	Enzyme	MGAM	Ki	'='	13400	nM
Q2M2H8	BXGT026100	Probable maltase-glucoamylase 2	reviewed	Enzyme	MGAM2	IC50	'='	17400	nM
P14410	BXGT008009	Sucrase-isomaltase, intestinal	reviewed	Enzyme	SI	IC50	'='	17400	nM
P10253	BXGT007550	Lysosomal alpha-glucosidase	reviewed	Enzyme	GAA	IC50	'='	17400	nM
O43451	BXGT004594	Maltase-glucoamylase, intestinal	reviewed	Enzyme	MGAM	IC50	'='	17400	nM
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	Ki	'='	3100	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF03915	Cratoxylum cochinchinense	Cratoxylum cochinchinense	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}