acompound

Showing entry for (2R,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-2,3-Dihydrochromen-4-One

General Compound Information
BXGC Id	BXGC0034712
Compound Name	(2R,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-2,3-Dihydrochromen-4-One
Structure
Formula	C15H12O7
InchiKey	CXQWRCVTCMQVQX-HUUCEWRRSA-N
SMILES	Oc1cc2O[C@H](c3ccc(c(c3)O)O)[C@@H](C(=O)c2c(c1)O)O
Inchi	InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15-/m1/s1
IUPAC	(2R,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one
Molecular Weight	304.06
Pubchem Id	712318
Chembl Id	CHEMBL221328

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL221328

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	7943	nM
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	17782	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	14125	nM
P06746	BXGT006496	DNA polymerase beta	reviewed	Enzyme	POLB	Potency	'='	3548	nM
P10253	BXGT007550	Lysosomal alpha-glucosidase	reviewed	Enzyme	GAA	Potency	'='	3162	nM
Q962Y6	BXGT019597	Thioredoxin glutathione reductase	unreviewed	-	TGR	Potency	'='	28183	nM
Q9UIF8	BXGT021718	Bromodomain adjacent to zinc finger domain protein 2B	reviewed	-	BAZ2B	Potency	-	79432	nM
P46063	BXGT010501	ATP-dependent DNA helicase Q1	reviewed	Enzyme	RECQL	Potency	'='	17782	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00093	Black walnut	Juglans nigra	Nuts
BXGF00106	Mango	Mangifera indica	Fruits
BXGF00129	Parsnip	Pastinaca sativa	Vegetables
BXGF00148	Almond	Prunus dulcis	Nuts
BXGF00183	Common thyme	Thymus vulgaris	Herbs and Spices
BXGF00204	Common grape	Vitis vinifera	Fruits
BXGF00213	European cranberry	Vaccinium oxycoccos	Fruits
BXGF00405	Quinoa	Chenopodium quinoa	Herbs and Spices
BXGF00931	Ipomoea digitata	Ipomoea digitata	Medicinal Plant
BXGF00953	Aconitum subcuneatum	Aconitum subcuneatum	Medicinal Plant
BXGF01025	Andira retusa	Andira retusa	Others
BXGF01034	Annona cornifolia	Annona cornifolia	Human Edible Plant
BXGF01089	Trifolium hybridum	Trifolium hybridum	Medicinal Plant
BXGF01105	Baeckea frutescens	Baeckea frutescens	Medicinal Plant
BXGF01174	Salvia syriaca	Salvia syriaca	Others
BXGF01198	Marrubium parviflorum	Marrubium parviflorum	Others
BXGF01204	Solanum laxum	Solanum laxum	Medicinal Plant
BXGF01249	Dyssodia anthemidifolia	Dyssodia anthemidifolia	Others
BXGF01285	Psathyrotes ramosissima	Psathyrotes ramosissima	Others
BXGF01298	Lychnophora pinaster	Lychnophora pinaster	Others
BXGF01316	Stemodia maritima	Stemodia maritima	Others
BXGF01324	Albizia julibrissin	Albizia julibrissin	Medicinal Plant
BXGF01341	Trachelospermum jasminoides	Trachelospermum jasminoides	Medicinal Plant
BXGF01436	Rapanea neurophylla	Rapanea neurophylla	Medicinal Plant
BXGF01456	Eucalyptus melliodora	Eucalyptus melliodora	Others
BXGF01486	Lespedeza maximowiczi	Lespedeza maximowiczi	Others
BXGF01490	Leucocarpus perfoliatus	Leucocarpus perfoliatus	Others
BXGF01506	Thymus quinquecostatus	Thymus quinquecostatus	Medicinal Plant
BXGF01555	Scutellaria amoena	Scutellaria amoena	Medicinal Plant
BXGF01569	Coprosma foetidissima	Coprosma foetidissima	Medicinal Plant
BXGF01614	Goniothalamus malayanus	Goniothalamus malayanus	Others
BXGF01659	Microglossa pyrifolia	Microglossa pyrifolia	Medicinal Plant
BXGF01708	Narcissus concolor	Narcissus concolor	Others
BXGF01721	Humulus lupulus	Humulus lupulus	Medicinal Plant
BXGF01759	Parthenium confertum	Parthenium confertum	Others
BXGF01796	Harpullia cupanioides	Harpullia cupanioides	Others
BXGF01806	Rhododendron mucronatum	Rhododendron mucronatum	Medicinal Plant
BXGF01819	Trifolium diffusum	Trifolium diffusum	Others
BXGF01825	Youngia japonica	Youngia japonica	Medicinal Plant
BXGF01834	Lysimachia mauritiana	Lysimachia mauritiana	Others
BXGF01847	Eriocephalus kingesii	Eriocephalus kingesii	Others
BXGF01877	Balanophora polyandra	Balanophora polyandra	Medicinal Plant
BXGF01883	Swertia franchetiana	Swertia franchetiana	Medicinal Plant
BXGF01910	Trachelospermum asiaticum	Trachelospermum asiaticum	Medicinal Plant
BXGF01923	Lilium rubrum	Lilium rubrum	Others
BXGF01943	Lobelia syphilitica	Lobelia syphilitica	Others
BXGF01989	Helipterum roseum	Helipterum roseum	Others
BXGF02010	Cryptocarya chinensis	Cryptocarya chinensis	Medicinal Plant
BXGF02050	Hedysarum connatum	Hedysarum connatum	Others
BXGF02088	Zanthoxylum tetraspermum	Zanthoxylum tetraspermum	Medicinal Plant
BXGF02106	Citrus medica	Citrus medica	Medicinal Plant
BXGF02125	Artemisia assoana	Artemisia assoana	Others
BXGF02183	Dumortiera hirsuta	Dumortiera hirsuta	Medicinal Plant
BXGF02184	Panicum crus-galli	Panicum crus-galli	Medicinal Plant
BXGF02210	Scleropyrum wallichianum	Scleropyrum wallichianum	Medicinal Plant
BXGF02246	Lepisorus ussuriensis	Lepisorus ussuriensis	Medicinal Plant
BXGF02295	Alstonia spathulata	Alstonia spathulata	Others
BXGF02326	Phoebe pittieri	Phoebe pittieri	Others
BXGF02361	Hypericum laricifolium	Hypericum laricifolium	Medicinal Plant
BXGF02410	Adiantum lunulatum	Adiantum lunulatum	Medicinal Plant
BXGF02460	Peltostigma guatemalense	Peltostigma guatemalense	Others
BXGF02491	Acacia adunca	Acacia adunca	Others
BXGF02515	Viguiera incana	Viguiera incana	Others
BXGF02529	Astragalus sempervirens	Astragalus sempervirens	Others
BXGF02543	Rhododendron mucronulatum	Rhododendron mucronulatum	Medicinal Plant
BXGF02551	Inula britannica	Inula britannica	Medicinal Plant
BXGF02554	Marrubium anisodon	Marrubium anisodon	Medicinal Plant
BXGF02593	Wikstroemia retusa	Wikstroemia retusa	Others
BXGF02606	Naucleopsis ternstroemiiflora	Naucleopsis ternstroemiiflora	Others
BXGF02862	Isodon eriocalyx	Isodon eriocalyx	Others
BXGF02874	Tadehagi triquetrum	Tadehagi triquetrum	Medicinal Plant
BXGF02890	Veronica stricta	Veronica stricta	Others
BXGF03134	Zanthoxylum ocumarense	Zanthoxylum ocumarense	Others
BXGF03189	Rhododendron dauricum	Rhododendron dauricum	Medicinal Plant
BXGF03610	Bistorta officinalis	Bistorta officinalis	Medicinal Plant
BXGF03791	Pistacia chinensis	Pistacia chinensis	Medicinal Plant
BXGF03898	Dioscorea polystachya	Dioscorea polystachya	Medicinal Plant
BXGF03947	Rumex maritimus	Rumex maritimus	Medicinal Plant
BXGF04053	Smilax china	Smilax china	Medicinal Plant
BXGF04062	Spatholobus suberectus	Spatholobus suberectus	Medicinal Plant
BXGF04080	Persicaria orientalis	Persicaria orientalis	Medicinal Plant
BXGF04177	Cordylanthus kingii	Cordylanthus kingii	Others
BXGF04189	Phymatopteris hastata	Phymatopteris hastata	Others
BXGF04209	Chaenomeles sinensis	Chaenomeles sinensis	Medicinal Plant
BXGF04224	Bistorta manshuriensis	Bistorta manshuriensis	Others
BXGF04401	Annona impressivenia	Annona impressivenia	Others
BXGF04607	Morus alba	Morus alba	Medicinal Plant
BXGF04728	Alseodaphne corneri	Alseodaphne corneri	Others
BXGF04730	Thymus piperella	Thymus piperella	Human Edible Plant
BXGF04739	Forsteronia refracta	Forsteronia refracta	Others
BXGF04742	Eragrostis viscosa	Eragrostis viscosa	Medicinal Plant
BXGF04747	Nauclea officinalis	Nauclea officinalis	Medicinal Plant
BXGF04753	Grewia mollis	Grewia mollis	Medicinal Plant
BXGF04765	Heterotheca grandiflora	Heterotheca grandiflora	Others
BXGF04771	Croton cumingii	Croton cumingii	Medicinal Plant
BXGF04775	Bersama yangambiensis	Bersama yangambiensis	Others
BXGF04783	Ruta pinnata	Ruta pinnata	Medicinal Plant
BXGF04795	Disynaphia halimifolia	Disynaphia halimifolia	Others
BXGF04812	Meconopsis punicea	Meconopsis punicea	Medicinal Plant
BXGF04821	Kaunia saltensis	Kaunia saltensis	Others
BXGF04826	Heliotropium floridum	Heliotropium floridum	Others
BXGF04835	Castanopsis sclerophylla	Castanopsis sclerophylla	Medicinal Plant
BXGF04839	Gymnocarpium robertianum	Gymnocarpium robertianum	Others
BXGF04846	Oncoba echinata	Oncoba echinata	Others
BXGF04851	Salvia dorrii	Salvia dorrii	Others
BXGF04858	Teucrium depressum	Teucrium depressum	Others
BXGF04866	Aconitum nevadense	Aconitum nevadense	Others
BXGF04871	Trichilia rubescens	Trichilia rubescens	Others
BXGF04874	Conocephalum japonicum	Conocephalum japonicum	Others
BXGF04880	Hovenia acerba	Hovenia acerba	Medicinal Plant
BXGF04885	Stevia polycephala	Stevia polycephala	Others
BXGF04893	Sophora angustifolia	Sophora angustifolia	Others
BXGF04901	Kaempferia marginata	Kaempferia marginata	Medicinal Plant
BXGF04925	Pistacia atlantica	Pistacia atlantica	Medicinal Plant
BXGF04953	Polygonum aviculare	Polygonum aviculare	Medicinal Plant
BXGF05064	Fridericia chica	Fridericia chica	Medicinal Plant
BXGF05106	Geranium collinum	Geranium collinum	Others
BXGF05187	Calostephane divaricata	Calostephane divaricata	Others
BXGF05245	Doodia picta	Doodia picta	Others
BXGF05384	Polygonatum polyanthemum	Polygonatum polyanthemum	Others
BXGF05425	Elaphoglossum lindbergii	Elaphoglossum lindbergii	Others
BXGF05514	Rogeria adenophylla	Rogeria adenophylla	Human Edible Plant
BXGF05607	Chenopodiastrum murale	Chenopodiastrum murale	Medicinal Plant
BXGF05610	Girgensohnia oppositiflora	Girgensohnia oppositiflora	Others
BXGF05670	Scrophularia buergeriana	Scrophularia buergeriana	Medicinal Plant
BXGF05728	Persicaria perfoliata	Persicaria perfoliata	Medicinal Plant
BXGF05742	Caragana aurantiaca	Caragana aurantiaca	Others
BXGF05771	Davidsonia pruriens	Davidsonia pruriens	Human Edible Plant
BXGF05787	Smilax glabra	Smilax glabra	Medicinal Plant
BXGF05862	Premna odorata	Premna odorata	Medicinal Plant
BXGF06037	Cotyledon secunda	Cotyledon secunda	Others
BXGF06065	Aralia hispida	Aralia hispida	Medicinal Plant
BXGF06156	Inula japonica	Inula japonica	Medicinal Plant
BXGF06207	Ferula ammoniacum	Ferula ammoniacum	Medicinal Plant
BXGF06227	Rauvolfia vomitoria	Rauvolfia vomitoria	Medicinal Plant
BXGF06237	Gnetum latifolium	Gnetum latifolium	Medicinal Plant
BXGF06259	Castanea dentata	Castanea dentata	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}