acompound

Showing entry for Tetrahydrocurcumin

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0040733
Compound Name	Tetrahydrocurcumin
Structure
Formula	C21H24O6
InchiKey	PNTMRHGYQCMNCZ-SSZFMOIBSA-N
SMILES	COc1cc(CC/C(=C/C(=O)CCc2ccc(c(c2)OC)O)/O)ccc1O
Inchi	InChI=1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-13,22,24-25H,3-4,7-8H2,1-2H3/b16-13-
IUPAC	(Z)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-4-en-3-one
Molecular Weight	372.16
Pubchem Id	11895692
Chembl Id	CHEMBL2323724

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P10276	BXGT007553	Retinoic acid receptor alpha	reviewed	Nuclear receptor	RARA	Activity	-	-	-
P10826	BXGT007622	Retinoic acid receptor beta	reviewed	Nuclear receptor	RARB	Activity	-	-	-
P13631	BXGT007929	Retinoic acid receptor gamma	reviewed	Nuclear receptor	RARG	Activity	-	-	-
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	reviewed	Nuclear receptor	RXRA	Activity	-	-	-
P48443	BXGT010631	Retinoic acid receptor RXR-gamma	reviewed	Nuclear receptor	RXRG	Activity	-	-	-
P28702	BXGT009287	Retinoic acid receptor RXR-beta	reviewed	Nuclear receptor	RXRB	Activity	-	-	-
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Activity	-	-	-
P56817	BXGT011200	Beta-secretase 1	reviewed	Enzyme	BACE1	Inhibition	'='	7	%
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	Activity	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF03733	Alpinia officinarum	Alpinia officinarum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}