Showing entry for Retinoic acid receptor gamma


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007929
Protein NameRetinoic acid receptor gamma
Uniport IdP13631
GeneRARG
Gene Id5916
DomainHormone_recep; zf-C4
Pfam PF00104   PF00105  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009952 anterior/posterior pattern specification
Biological Process GO:0060070 canonical Wnt signaling pathway
Biological Process GO:0030154 cell differentiation
Biological Process GO:1990830 cellular response to leukemia inhibitory factor
Biological Process GO:0071300 cellular response to retinoic acid
Biological Process GO:0031076 embryonic camera-type eye development
Biological Process GO:0048048 embryonic eye morphogenesis
Biological Process GO:0035116 embryonic hindlimb morphogenesis
Biological Process GO:0060324 face development
Biological Process GO:0002068 glandular epithelial cell development
Biological Process GO:0003430 growth plate cartilage chondrocyte growth
Biological Process GO:0070384 Harderian gland development
Biological Process GO:0009755 hormone-mediated signaling pathway
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0032331 negative regulation of chondrocyte differentiation
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0001843 neural tube closure
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0043068 positive regulation of programmed cell death
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0060740 prostate gland epithelium morphogenesis
Biological Process GO:0008361 regulation of cell size
Biological Process GO:0031641 regulation of myelination
Biological Process GO:0045637 regulation of myeloid cell differentiation
Biological Process GO:0032526 response to retinoic acid
Biological Process GO:0048384 retinoic acid receptor signaling pathway
Biological Process GO:0060534 trachea cartilage development
Biological Process GO:0006367 transcription initiation from RNA polymerase II promoter
molecular function GO:0003677 DNA binding
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0046965 retinoid X receptor binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0008134 transcription factor binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0016021 integral component of membrane
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0090575 RNA polymerase II transcription regulator complex
cellular component GO:0005667 transcription regulator complex
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-162582 Signal Transduction
R-HSA-212436 Generic Transcription Pathway
R-HSA-383280 Nuclear Receptor transcription pathway
R-HSA-5362517 Signaling by Retinoic Acid
R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis
R-HSA-5619507 Activation of HOX genes during differentiation
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-9006931 Signaling by Nuclear Receptors
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002893 BXGD000150 Refractory anemias Hemic and Lymphatic Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0008479 BXGD000544 Chondrosarcoma Neoplasms
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010418 BXGD000671 Cryptosporidiosis Digestive System Diseases; Infections; Animal Diseases
C0016037 BXGD001035 Fibrodysplasia Ossificans Progressiva Musculoskeletal Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0023418 BXGD001642 leukemia Neoplasms
C0023440 BXGD001646 Acute Erythroblastic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029423 BXGD002143 Cartilaginous exostosis Neoplasms; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0042834 BXGD003004 Vital capacity
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0151491 BXGD003428 Congenital musculoskeletal anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0206659 BXGD004222 Embryonal Carcinoma Neoplasms
C0206664 BXGD004226 Teratocarcinoma Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0278704 BXGD006567 Malignant Childhood Neoplasm Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0334037 BXGD006980 Intestinal metaplasia
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740277 BXGD009972 Bile duct carcinoma Digestive System Diseases; Neoplasms
C0876994 BXGD011324 Cardiotoxicity Pathological Conditions, Signs and Symptoms; Chemically-Induced Disorders; Cardiovascular Diseases; Wounds and Injuries
C0920350 BXGD011466 Autoimmune thyroiditis Immune System Diseases; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1837218 BXGD014207 Cleft palate, isolated Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2347748 BXGD017041 Adult Erythroleukemia
C2937421 BXGD018162 Prostatic Hyperplasia Male Urogenital Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4520840 BXGD023041 Erythroleukemia (Erythroid/Myeloid) Neoplasms; Hemic and Lymphatic Diseases
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0012874 Continentalic acid 302.22
BXGC0013582 Curcumin 368.13
BXGC0030612 tetraethylene glycol 194.12
BXGC0037954 Pimaric Acid 302.22
BXGC0040733 Tetrahydrocurcumin 372.16
BXGC0041564 Abietic Acid 302.22
BXGC0042413 Calcitriol 416.33
BXGC0051342 Valerenic Acid 234.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein