acompound

Showing entry for Dihydroresveratrol

General Compound Information
BXGC Id	BXGC0040952
Compound Name	Dihydroresveratrol
Structure
Formula	C14H14O3
InchiKey	HITJFUSPLYBJPE-UHFFFAOYSA-N
SMILES	Oc1ccc(cc1)CCc1cc(O)cc(c1)O
Inchi	InChI=1S/C14H14O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h3-9,15-17H,1-2H2
IUPAC	5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol
Molecular Weight	230.09
Pubchem Id	185914
Chembl Id	CHEMBL111234

Targets of Information Source

DrugBank

DB08466

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P09960	BXGT006952	Leukotriene A-4 hydrolase	reviewed	-	LTA4H	experimental	-

PDB

RE2

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P09960	BXGT006952	Leukotriene A-4 hydrolase	reviewed	LTA4H	-	-	247000	-	-
P09960	BXGT006952	Leukotriene A-4 hydrolase	reviewed	LTA4H	-	-	-	-	-

Binding DB

50085531

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006952	Leukotriene A-4 hydrolase	reviewed		LTA4H	-	247000	-	-
reviewed	BXGT006952	Leukotriene A-4 hydrolase	reviewed		LTA4H	-	145000	-	-
reviewed	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	-	>50000	-	-

CHEMBL

CHEMBL111234

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q64669	BXGT016128	NAD(P)H dehydrogenase [quinone] 1	reviewed	-	Nqo1	Ratio	'='	1	-
P11511	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	IC50	'>'	50000	nM
Q64669	BXGT016128	NAD(P)H dehydrogenase [quinone] 1	reviewed	-	Nqo1	Ratio	-	-	-
P62157	BXGT011410	Calmodulin	reviewed	-	CALM	Activity	-	-	-
P09960	BXGT006952	Leukotriene A-4 hydrolase	reviewed	-	LTA4H	IC50	'='	247000	nM
P09960	BXGT006952	Leukotriene A-4 hydrolase	reviewed	-	LTA4H	IC50	'='	145000	nM
Q64669	BXGT016128	NAD(P)H dehydrogenase [quinone] 1	reviewed	-	Nqo1	CD	'>'	50	uM
Q64669	BXGT016128	NAD(P)H dehydrogenase [quinone] 1	reviewed	-	Nqo1	Survival	'='	82	%
P02766	BXGT005953	Transthyretin	reviewed	Transporter	TTR	Inhibition	'='	30	%
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	reviewed	Ion channel	TRPA1	Inhibition	'='	-10	%
P11511	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	Imax	'='	37	%
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	reviewed	Ion channel	TRPA1	Inhibition	'='	-12	%
P14679	BXGT008039	Tyrosinase	reviewed	Enzyme	TYR	Activity	'='	78	%
P02766	BXGT005953	Transthyretin	reviewed	Transporter	TTR	Activity_index	'='	0	-
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	reviewed	Ion channel	TRPA1	FC	'='	1	-
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	reviewed	Ion channel	TRPA1	EC50	'>'	30000	nM
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	reviewed	Ion channel	TRPA1	IC50	'>'	30000	nM
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	reviewed	Ion channel	TRPA1	Inhibition	'='	1	%
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	reviewed	Ion channel	TRPA1	FC	'='	0	-
P11344	BXGT007687	Tyrosinase	reviewed	-	Tyr	Activity	'='	78	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00148	Almond	Prunus dulcis	Nuts
BXGF01267	Dendrobium chrysanthum	Dendrobium chrysanthum	Medicinal Plant
BXGF01806	Rhododendron mucronatum	Rhododendron mucronatum	Medicinal Plant
BXGF02543	Rhododendron mucronulatum	Rhododendron mucronulatum	Medicinal Plant
BXGF03161	Dendrobium chrysotoxum	Dendrobium chrysotoxum	Medicinal Plant
BXGF03189	Rhododendron dauricum	Rhododendron dauricum	Medicinal Plant
BXGF03346	Dendrobium candidum	Dendrobium candidum	Others
BXGF03632	Dendrobium fimbriatum	Dendrobium fimbriatum	Medicinal Plant
BXGF03791	Pistacia chinensis	Pistacia chinensis	Medicinal Plant
BXGF05173	Dendrobium nobile	Dendrobium nobile	Medicinal Plant
BXGF05787	Smilax glabra	Smilax glabra	Medicinal Plant
BXGF05853	Cannabis sativa	Cannabis sativa	Medicinal Plant
BXGF06069	Dendrobium loddigesii	Dendrobium loddigesii	Medicinal Plant
BXGF06095	Rheum undulatum	Rheum undulatum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}