Showing entry for Questiomycin B


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0041894
Compound NameQuestiomycin B
Structure
FormulaC6H7NO
InchiKeyCDAWCLOXVUBKRW-UHFFFAOYSA-N
SMILESNc1ccccc1O
InchiInChI=1S/C6H7NO/c7-5-3-1-2-4-6(5)8/h1-4,8H,7H2
IUPAC2-aminophenol
Molecular Weight109.05
Pubchem Id5801
Chembl IdCHEMBL28319
Targets of Information Source
DrugBank DB01726
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Q05603 BXGT012829 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase reviewed - cobT experimental -
PDB 2AF
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Q05603 BXGT012829 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase reviewed cobT - - - - -
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL28319
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 20596 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 4109 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 22387 nM
P16050 BXGT008184 Arachidonate 15-lipoxygenase reviewed Enzyme ALOX15 Potency '=' 39810 nM
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial reviewed Enzyme GLS Potency - 19952 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 7307 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 13333 nM
Q9BY64 BXGT020182 UDP-glucuronosyltransferase 2B28 reviewed - UGT2B28 Activity - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 20596 nM
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 reviewed - UGT1A7 Activity '=' 0 pm/min/mg
Q96RI1 BXGT019727 Bile acid receptor reviewed Nuclear receptor NR1H4 Potency - 12589 nM
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 28183 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 11220 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 3548 nM
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 reviewed - UGT1A10 Activity '=' 0 pm/min/mg
P51449 BXGT010846 Nuclear receptor ROR-gamma reviewed Nuclear receptor RORC Potency - 37578 nM
P11308 BXGT007684 Transcriptional regulator ERG reviewed Transcription factor ERG Potency - 44668 nM
P16473 BXGT008234 Thyrotropin receptor reviewed G-protein coupled receptor TSHR Potency '=' 10000 nM
P06133 BXGT006414 UDP-glucuronosyltransferase 2B4 reviewed - UGT2B4 Activity '=' 0 pm/min/mg
P36537 BXGT009924 UDP-glucuronosyltransferase 2B10 reviewed - UGT2B10 Activity '=' 0 pm/min/mg
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 0 pm/min/mg
P35869 BXGT009877 Aryl hydrocarbon receptor reviewed Transcription factor AHR Potency - 12589 nM
P22310 BXGT008754 UDP-glucuronosyltransferase 1-4 reviewed - UGT1A4 Activity '=' 0 pm/min/mg
Q962Y6 BXGT019597 Thioredoxin glutathione reductase unreviewed - TGR Potency '=' 56234 nM
P10145 BXGT007542 Interleukin-8 reviewed Signaling CXCL8 Potency - 66824 nM
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 reviewed Transcription factor SMAD3 Potency - 35481 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 16360 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF04920 Aconitum carmichaeli Aconitum carmichaeli Medicinal Plant
BXGF05365 Aconitum carmichaelii Aconitum carmichaelii Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease