acompound

Showing entry for Anthraflavicacid

General Compound Information
BXGC Id	BXGC0052712
Compound Name	Anthraflavicacid
Structure
Formula	C14H8O4
InchiKey	APAJFZPFBHMFQR-UHFFFAOYSA-N
SMILES	Oc1ccc2c(c1)C(=O)c1c(C2=O)cc(cc1)O
Inchi	InChI=1S/C14H8O4/c15-7-1-3-9-11(5-7)14(18)10-4-2-8(16)6-12(10)13(9)17/h1-6,15-16H
IUPAC	2,6-dihydroxyanthracene-9,10-dione
Molecular Weight	240.04
Pubchem Id	6776
Chembl Id	CHEMBL298398

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50101979

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	690	-	-	-
reviewed	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	-	2400	-	-
reviewed	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	-	1100	-	-
reviewed	BXGT008753	UDP-glucuronosyltransferase 1-1	reviewed		UGT1A1	-	4000	-	-
reviewed	BXGT008753	UDP-glucuronosyltransferase 1-1	reviewed		UGT1A1	-	3600	-	-
reviewed	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	310	-	-	-

CHEMBL

CHEMBL298398

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	Control	'<'	170	%
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	Control	'<'	170	%
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	IC50	'='	2400	nM
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	Ki	'='	690	nM
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	Control	'<'	164	%
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	Control	'<'	164	%
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	Control	'='	167	%
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	Control	'='	167	%
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	Ki	'='	310	nM
P0DTE4	BXGT022286	UDP-glucuronosyltransferase 2A1	reviewed	-	UGT2A1	Activity	'='	210	pm/min/mg
P22310	BXGT008754	UDP-glucuronosyltransferase 1-4	reviewed	-	UGT1A4	Activity	'='	0	pm/min/mg
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	reviewed	-	UGT1A1	IC50	'='	3600	nM
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	reviewed	-	UGT1A1	Activity	'='	206	pm/min/mg
P54855	BXGT011088	UDP-glucuronosyltransferase 2B15	reviewed	-	UGT2B15	Activity	'='	19	pm/min/mg
Q9HAW8	BXGT020509	UDP-glucuronosyltransferase 1-10	reviewed	-	UGT1A10	Activity	'='	79	pm/min/mg
P19224	BXGT008468	UDP-glucuronosyltransferase 1-6	reviewed	-	UGT1A6	Activity	'='	0	pm/min/mg
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	reviewed	-	UGT1A1	Activity	'='	1720	pm/min/mg
P35503	BXGT009840	UDP-glucuronosyltransferase 1-3	reviewed	-	UGT1A3	Activity	'='	149	pm/min/mg
Q9HAW9	BXGT020510	UDP-glucuronosyltransferase 1-8	reviewed	-	UGT1A8	Activity	'='	806	pm/min/mg
O60656	BXGT004889	UDP-glucuronosyltransferase 1-9	reviewed	-	UGT1A9	Activity	'='	1600	pm/min/mg
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	reviewed	-	UGT1A1	IC50	'='	4000	nM
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	IC50	'='	1100	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF01126	Polygonum cuspidatum	Polygonum cuspidatum	Medicinal Plant
BXGF03158	Rheum officinale	Rheum officinale	Medicinal Plant
BXGF03988	Rheum coreanum	Rheum coreanum	Others
BXGF04539	Rheum palmatum	Rheum palmatum	Medicinal Plant
BXGF05877	Rheum tanguticum	Rheum tanguticum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}