acompound

Showing entry for Ornithine

General Compound Information
BXGC Id	BXGC0052927
Compound Name	Ornithine
Structure
Formula	C5H12N2O2
InchiKey	AHLPHDHHMVZTML-BYPYZUCNSA-N
SMILES	N[C@H](C(=O)O)CCCN
Inchi	InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
IUPAC	(2S)-2,5-diaminopentanoate;hydron
Molecular Weight	132.09
Pubchem Id	6262
Chembl Id	CHEMBL446143

Targets of Information Source

DrugBank

DB00129

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P04181	BXGT006165	Ornithine aminotransferase, mitochondrial	reviewed	Enzyme	OAT	approved; nutraceutical	-
P00480	BXGT005551	Ornithine carbamoyltransferase, mitochondrial	reviewed	-	OTC	approved; nutraceutical	-
P05089	BXGT006310	Arginase-1	reviewed	Enzyme	ARG1	approved; nutraceutical	-
P54368	BXGT011046	Ornithine decarboxylase antizyme 1	reviewed	Enzyme modulator	OAZ1	approved; nutraceutical	-
P30825	BXGT009469	High affinity cationic amino acid transporter 1	reviewed	Transporter	SLC7A1	approved; nutraceutical	-
P52569	BXGT010934	Cationic amino acid transporter 2	reviewed	Transporter	SLC7A2	approved; nutraceutical	-
Q9BXI2	BXGT020168	Mitochondrial ornithine transporter 2	reviewed	Transporter	SLC25A2	approved; nutraceutical	-
P78540	BXGT011848	Arginase-2, mitochondrial	reviewed	Enzyme	ARG2	approved; nutraceutical	-
Q9Y619	BXGT022316	Mitochondrial ornithine transporter 1	reviewed	Transporter	SLC25A15	approved; nutraceutical	-
P50440	BXGT010798	Glycine amidinotransferase, mitochondrial	reviewed	-	GATM	approved; nutraceutical	-

PDB

ORN

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P00968	BXGT005708	Carbamoyl-phosphate synthase large chain	reviewed	carB	-	-	-	-	-
P07824	BXGT006682	Arginase-1	reviewed	Arg1	-	-	-	-	-
P02911	BXGT005987	Lysine/arginine/ornithine-binding periplasmic protein	reviewed	argT	-	-	-	30	-
Q88H32	BXGT017714	Ornithine cyclodeaminase	reviewed	ocd	-	-	-	-	-
P05089	BXGT006310	Arginase-1	reviewed	ARG1	Enzyme	-	-	-	-
P9WPZ3	BXGT012482	Arginine biosynthesis bifunctional protein ArgJ	reviewed	argJ	-	-	-	-	-
P50440	BXGT010798	Glycine amidinotransferase, mitochondrial	reviewed	GATM	-	253000	-	-	-
Q51548	BXGT014954	L-ornithine N(5)-monooxygenase	reviewed	pvdA	-	-	-	-	-
Q72JG5	BXGT016745	Amino acid ABC transporter, binding protein	unreviewed	TT_C0807	-	-	-	-	-
E9QYP0	BXGT003194	L-ornithine N(5)-monooxygenase	reviewed	sidA	-	-	-	-	-
P53608	BXGT011000	Arginase	reviewed	rocF	-	-	-	-	-
P51541	BXGT010853	Arginine kinase	reviewed		-	-	-	-	-
Q6TUJ5	BXGT016554	Arginase	unreviewed	ARG	-	-	-	-	-
Q6WVP6	BXGT016599	Arginase	unreviewed	Smp_059980	-	-	-	-	-
A8CF85	BXGT001675	KtzI	unreviewed	ktzI	-	-	-	-	-
P61769	BXGT011383	Beta-2-microglobulin	reviewed	B2M	Immune response	-	-	-	-
B3BM80	BXGT002027	Deoxyribonuclease CdiA-o11	reviewed	cdiA4	-	-	-	-	-
W6JQJ6	BXGT022627	L-amino acid oxidase/monooxygenase	unreviewed	laao	-	-	-	-	-
C4LSS0	BXGT023621	Arginase	unreviewed	EHI_152330	-	-	-	-	-
P01308	BXGT005749	Insulin	reviewed	INS	-	-	-	-	-
P74535	BXGT024545	Sll1336 protein	unreviewed	sll1336	-	-	-	-	-
P08650	BXGT024547	Complement C5 [Cleaved into: C5a anaphylatoxin]	reviewed	C5	-	-	-	-	-
Q8YMD9	BXGT024780	Alr4995 protein	unreviewed	alr4995	-	-	-	-	-
P60242	BXGT011295	Competence-stimulating peptide type 1	reviewed	comC1	-	-	-	-	-
P08047	BXGT006720	Transcription factor Sp1	reviewed	SP1	Nucleic acid binding	-	-	-	-
G7JFU5	BXGT025846	Arginase family protein	unreviewed	11420737	-	-	-	-	-
P46637	BXGT025847	Arginase 1, mitochondrial	reviewed	ARGAH1	-	-	-	-	-
P05067	BXGT006306	Amyloid-beta precursor protein	reviewed	APP	Enzyme modulator	-	-	-	-

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL446143

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P11926	BXGT007760	Ornithine decarboxylase	reviewed	Enzyme	ODC1	Kd	'='	250000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00008	Garlic	Allium sativum	Herbs and Spices
BXGF01140	Angelica gigas	Angelica gigas	Medicinal Plant
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF02567	Lycium chinense	Lycium chinense	Medicinal Plant
BXGF03645	Lycium barbarum	Lycium barbarum	Medicinal Plant
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant
BXGF05203	Chlamydomonas reinhardtii	Chlamydomonas reinhardtii	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}