Showing entry for Ornithine aminotransferase, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006165
Protein NameOrnithine aminotransferase, mitochondrial
Uniport IdP04181
GeneOAT
Gene Id4942
DomainAminotran_3
Pfam PF00202  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00330 Arginine and proline metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019544 arginine catabolic process to glutamate
Biological Process GO:0010121 arginine catabolic process to proline via ornithine
Biological Process GO:0008652 cellular amino acid biosynthetic process
Biological Process GO:0055129 L-proline biosynthetic process
Biological Process GO:0007601 visual perception
molecular function GO:0042802 identical protein binding
molecular function GO:0050155 ornithine(lysine) transaminase activity
molecular function GO:0004587 ornithine-oxo-acid transaminase activity
molecular function GO:0030170 pyridoxal phosphate binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-71291 Metabolism of amino acids and derivatives
R-HSA-8964539 Glutamate and glutamine metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002514 BXGD000118 Amino Acid Metabolism, Inborn Errors Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004277 BXGD000266 Tooth Attrition Stomatognathic Diseases
C0004509 BXGD000275 Azoospermia Male Urogenital Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0015503 BXGD000998 Factor VII Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0018425 BXGD001193 Gyrate Atrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0019621 BXGD001340 Histiocytosis, Langerhans-Cell Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0022672 BXGD001574 Acute Kidney Tubular Necrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023381 BXGD001641 Letterer-Siwe Disease Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024440 BXGD001774 Macular Edema, Cystoid Eye Diseases
C0025521 BXGD001876 Inborn Errors of Metabolism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0028077 BXGD002069 Nyctalopia Eye Diseases
C0028960 BXGD002101 Oligospermia Male Urogenital Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037579 BXGD002694 Soft Tissue Neoplasms Neoplasms
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0042798 BXGD003003 Low Vision Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220994 BXGD004357 Hyperammonemia Pathological Conditions, Signs and Symptoms
C0221629 BXGD004467 Proximal muscle weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0221715 BXGD004468 Intestinal carcinoma Digestive System Diseases; Neoplasms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235095 BXGD004723 Visual field constriction Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0235259 BXGD004735 Subcapsular cataract Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0238621 BXGD004947 Aminoaciduria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0266526 BXGD005687 Norrie disease Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C0268540 BXGD005976 HHH syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268647 BXGD006024 Lysinuric Protein Intolerance Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0278660 BXGD006555 Adult Synovial Sarcoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279982 BXGD006702 Childhood Synovial Sarcoma Neoplasms
C0339528 BXGD007261 X-linked retinitis pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0406317 BXGD008334 Chronic small plaque psoriasis Skin and Connective Tissue Diseases
C0410158 BXGD008408 Muscle damage
C0456909 BXGD008883 Blindness Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0476403 BXGD008992 Electromyogram abnormal
C0520459 BXGD009084 Necrotizing Enterocolitis Digestive System Diseases
C0599035 BXGD009675 Hyperornithinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0850673 BXGD010904 congenital metabolic disorder
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0856825 BXGD011118 Acute GVH disease Immune System Diseases
C0858617 BXGD011183 Posterior subcapsular cataract Eye Diseases
C0917801 BXGD011412 Sleeplessness Nervous System Diseases; Mental Disorders
C1136135 BXGD011710 Water Stress Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1285162 BXGD012167 Degenerative disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306837 BXGD012377 Papillary Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1839364 BXGD014371 Progressive visual loss
C1857627 BXGD015723 Chorioretinal dystrophy Eye Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2931728 BXGD018052 Distal Trisomy 10q Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C3665346 BXGD019278 Unspecified visual loss Pathological Conditions, Signs and Symptoms; Eye Diseases
C3887875 BXGD019923 Visual field defects Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4017305 BXGD020436 GYRATE ATROPHY OF CHOROID AND RETINA WITH PYRIDOXINE-RESPONSIVE ORNITHINEMIA
C4021107 BXGD020557 Non-obstructive azoospermia Male Urogenital Diseases
C4021768 BXGD020766 Abnormality of metabolism/homeostasis
C4022482 BXGD020903 Chorioretinal hyperpigmentation
C4024818 BXGD021428 Progressive night blindness Eye Diseases
C4025836 BXGD021820 Abnormal choroid morphology
C4048273 BXGD021898 Chorioretinal atrophy Eye Diseases
C4048329 BXGD021904 Immunosuppression
C4520679 BXGD023033 Abnormal macular morphology Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0017320 Canaline 134.07
BXGC0043088 Pyridoxal Phosphate 247.02
BXGC0052927 Ornithine 132.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein