adisease

Showing entry for Hereditary Multiple Exostoses

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD000975
Disease Name	Hereditary Multiple Exostoses
Disease CUI Id	C0015306
MeSH Codes	C16 C04 C05
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Musculoskeletal Diseases
Semantic Type	Congenital Abnormality
Human Phenotype Ontology Id	HP:0002664 HP:0000924
Human Phenotype Ontology Term	Neoplasm; Abnormality of the skeletal system
Disease Ontology Id	DOID:630 DOID:7
Disease Ontology Class Name	genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P01130	BXGT005735	Low-density lipoprotein receptor	3949	reviewed
P27037	BXGT009153	Activin receptor type-2A	92	reviewed	Kinase
P31947	BXGT009589	14-3-3 protein sigma	2810	reviewed	Chaperone
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P39900	BXGT010148	Macrophage metalloelastase	4321	reviewed	Enzyme
P41279	BXGT010254	Mitogen-activated protein kinase kinase kinase 8	1326	reviewed	Kinase
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P49888	BXGT010756	Estrogen sulfotransferase	6783	reviewed
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q8NBZ7	BXGT018544	UDP-glucuronic acid decarboxylase 1	80146	reviewed	Enzyme
Q9UBQ6	BXGT021660	Exostosin-like 2	2135	reviewed
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}