adisease

General Disease Information
BXGD Id	BXGD001679
Disease Name	Globoid cell leukodystrophy
Disease CUI Id	C0023521
MeSH Codes	C16 C18 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0014667 DOID:630
Disease Ontology Class Name	disease of metabolism; genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P07602	BXGT006646	Prosaposin	5660	reviewed
P11717	BXGT007740	Cation-independent mannose-6-phosphate receptor	3482	reviewed	Receptor
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P28676	BXGT009284	Grancalcin	25801	reviewed
P35475	BXGT009837	Alpha-L-iduronidase	3425	reviewed	Enzyme
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P48506	BXGT010635	Glutamate--cysteine ligase catalytic subunit	2729	reviewed	Enzyme
P54803	BXGT011082	Galactocerebrosidase	2581	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
Q13231	BXGT013329	Chitotriosidase-1	1118	reviewed
Q13510	BXGT013367	Acid ceramidase	427	reviewed	Enzyme
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}