Showing entry for Alpha-synuclein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010015
Protein NameAlpha-synuclein
Uniport IdP37840
GeneSNCA
Gene Id6622
DomainSynuclein
Pfam PF01387  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.4 Neurodegenerative diseases hsa05010 Alzheimer disease
6. Human Diseases 6.4 Neurodegenerative diseases hsa05012 Parkinson disease
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0008344 adult locomotory behavior
Biological Process GO:0007568 aging
Biological Process GO:0048148 behavioral response to cocaine
Biological Process GO:0044267 cellular protein metabolic process
Biological Process GO:0071280 cellular response to copper ion
Biological Process GO:0071872 cellular response to epinephrine stimulus
Biological Process GO:0044344 cellular response to fibroblast growth factor stimulus
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0042416 dopamine biosynthetic process
Biological Process GO:0051583 dopamine uptake involved in synaptic transmission
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0006631 fatty acid metabolic process
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0001774 microglial cell activation
Biological Process GO:0042775 mitochondrial ATP synthesis coupled electron transport
Biological Process GO:0007006 mitochondrial membrane organization
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:1904715 negative regulation of chaperone-mediated autophagy
Biological Process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0045963 negative regulation of dopamine metabolic process
Biological Process GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission
Biological Process GO:0045920 negative regulation of exocytosis
Biological Process GO:0035067 negative regulation of histone acetylation
Biological Process GO:0031115 negative regulation of microtubule polymerization
Biological Process GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone
Biological Process GO:0032769 negative regulation of monooxygenase activity
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:0051622 negative regulation of norepinephrine uptake
Biological Process GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway
Biological Process GO:0006469 negative regulation of protein kinase activity
Biological Process GO:0051612 negative regulation of serotonin uptake
Biological Process GO:0070495 negative regulation of thrombin-activated receptor signaling pathway
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0032410 negative regulation of transporter activity
Biological Process GO:0006638 neutral lipid metabolic process
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0006644 phospholipid metabolic process
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0045807 positive regulation of endocytosis
Biological Process GO:0045921 positive regulation of exocytosis
Biological Process GO:1903284 positive regulation of glutathione peroxidase activity
Biological Process GO:1903285 positive regulation of hydrogen peroxide catabolic process
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0060732 positive regulation of inositol phosphate biosynthetic process
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0001956 positive regulation of neurotransmitter secretion
Biological Process GO:0033138 positive regulation of peptidyl-serine phosphorylation
Biological Process GO:0071902 positive regulation of protein serine/threonine kinase activity
Biological Process GO:0001921 positive regulation of receptor recycling
Biological Process GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Biological Process GO:0035543 positive regulation of SNARE complex assembly
Biological Process GO:0031648 protein destabilization
Biological Process GO:0051262 protein tetramerization
Biological Process GO:0031623 receptor internalization
Biological Process GO:0050812 regulation of acyl-CoA biosynthetic process
Biological Process GO:0014059 regulation of dopamine secretion
Biological Process GO:0014048 regulation of glutamate secretion
Biological Process GO:0040012 regulation of locomotion
Biological Process GO:0048169 regulation of long-term neuronal synaptic plasticity
Biological Process GO:0043030 regulation of macrophage activation
Biological Process GO:0051621 regulation of norepinephrine uptake
Biological Process GO:0010517 regulation of phospholipase activity
Biological Process GO:1905606 regulation of presynapse assembly
Biological Process GO:1903426 regulation of reactive oxygen species biosynthetic process
Biological Process GO:1903421 regulation of synaptic vesicle recycling
Biological Process GO:0022898 regulation of transmembrane transporter activity
Biological Process GO:1904307 response to desipramine
Biological Process GO:0042493 response to drug
Biological Process GO:0034341 response to interferon-gamma
Biological Process GO:0070555 response to interleukin-1
Biological Process GO:0010040 response to iron(II) ion
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0032026 response to magnesium ion
Biological Process GO:0035493 SNARE complex assembly
Biological Process GO:0097435 supramolecular fiber organization
Biological Process GO:0050808 synapse organization
Biological Process GO:0048488 synaptic vesicle endocytosis
Biological Process GO:0016079 synaptic vesicle exocytosis
Biological Process GO:0016082 synaptic vesicle priming
Biological Process GO:0048489 synaptic vesicle transport
molecular function GO:0003779 actin binding
molecular function GO:0043014 alpha-tubulin binding
molecular function GO:0048487 beta-tubulin binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0005507 copper ion binding
molecular function GO:1903136 cuprous ion binding
molecular function GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
molecular function GO:0070840 dynein complex binding
molecular function GO:0008198 ferrous iron binding
molecular function GO:0042393 histone binding
molecular function GO:0030544 Hsp70 protein binding
molecular function GO:0042802 identical protein binding
molecular function GO:0019894 kinesin binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0008017 microtubule binding
molecular function GO:0016491 oxidoreductase activity
molecular function GO:0043274 phospholipase binding
molecular function GO:0005543 phospholipid binding
molecular function GO:0051219 phosphoprotein binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0004860 protein kinase inhibitor activity
molecular function GO:0047485 protein N-terminus binding
molecular function GO:0000149 SNARE binding
molecular function GO:0048156 tau protein binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0030424 axon
cellular component GO:0005938 cell cortex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0005794 Golgi apparatus
cellular component GO:0030426 growth cone
cellular component GO:0016234 inclusion body
cellular component GO:0005764 lysosome
cellular component GO:0016020 membrane
cellular component GO:0005743 mitochondrial inner membrane
cellular component GO:0005758 mitochondrial intermembrane space
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005741 mitochondrial outer membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0043025 neuronal cell body
cellular component GO:0005640 nuclear outer membrane
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0005840 ribosome
cellular component GO:0005791 rough endoplasmic reticulum
cellular component GO:0099512 supramolecular fiber
cellular component GO:0030672 synaptic vesicle membrane
cellular component GO:0043195 terminal bouton
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-977225 Amyloid fiber formation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002622 BXGD000119 Amnesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0002874 BXGD000134 Aplastic Anemia Hemic and Lymphatic Diseases
C0003125 BXGD000179 Anorexia Nervosa Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003857 BXGD000228 Congenital arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005697 BXGD000324 Neurogenic Urinary Bladder Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Nervous System Diseases
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007820 BXGD000491 Cerebrovascular Disorders Nervous System Diseases; Cardiovascular Diseases
C0009081 BXGD000581 Congenital clubfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0009171 BXGD000587 Cocaine Abuse Chemically-Induced Disorders; Mental Disorders
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009398 BXGD000604 Color vision defect Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009782 BXGD000631 Connective Tissue Diseases Skin and Connective Tissue Diseases
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011168 BXGD000700 Deglutition Disorders Digestive System Diseases; Otorhinolaryngologic Diseases
C0011253 BXGD000706 Delusions Behavior and Behavior Mechanisms
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011268 BXGD000709 Senile dementia Nervous System Diseases; Mental Disorders
C0011269 BXGD000710 Dementia, Vascular Nervous System Diseases; Mental Disorders; Cardiovascular Diseases
C0011303 BXGD000712 Demyelinating Diseases Nervous System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011989 BXGD000765 Camurati-Engelmann Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0012236 BXGD000772 DiGeorge Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0012569 BXGD000777 Diplopia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013363 BXGD000818 Dysautonomia Nervous System Diseases
C0013384 BXGD000826 Dyskinetic syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013421 BXGD000837 Dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013473 BXGD000845 Eating Disorders Mental Disorders
C0013537 BXGD000853 Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014474 BXGD000917 Ependymoma Neoplasms
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017185 BXGD001104 Gastrointestinal Neoplasms Digestive System Diseases; Neoplasms
C0017205 BXGD001105 Gaucher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017639 BXGD001133 Gliosis Pathological Conditions, Signs and Symptoms
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018523 BXGD001199 Hallervorden-Spatz Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0018524 BXGD001200 Hallucinations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019202 BXGD001302 Hepatolenticular Degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020651 BXGD001460 Hypotension, Orthostatic Nervous System Diseases; Cardiovascular Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021125 BXGD001483 Impulsive Behavior Behavior and Behavior Mechanisms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022336 BXGD001535 Creutzfeldt-Jakob disease Infections; Nervous System Diseases; Mental Disorders
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023521 BXGD001679 Globoid cell leukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024408 BXGD001768 Machado-Joseph Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0024899 BXGD001812 Mastocytosis Neoplasms; Skin and Connective Tissue Diseases; Immune System Diseases
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0026269 BXGD001897 Mitral Valve Stenosis Cardiovascular Diseases
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026691 BXGD001917 Mucocutaneous Lymph Node Syndrome Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026706 BXGD001921 Mucopolysaccharidosis III Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0027066 BXGD001966 Myoclonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027497 BXGD001993 Nausea Pathological Conditions, Signs and Symptoms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027746 BXGD002032 Nerve Degeneration Pathological Conditions, Signs and Symptoms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027809 BXGD002040 Neurilemmoma Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027877 BXGD002055 Neuronal Ceroid-Lipofuscinoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028968 BXGD002103 Olivopontocerebellar Atrophies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030508 BXGD002233 Parasomnia Nervous System Diseases; Mental Disorders
C0030552 BXGD002238 Paresis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0030569 BXGD002242 Secondary Parkinson Disease Nervous System Diseases
C0031511 BXGD002304 Pheochromocytoma Neoplasms
C0033937 BXGD002442 Psychoses, Drug Chemically-Induced Disorders; Mental Disorders
C0033941 BXGD002443 Psychoses, Substance-Induced Chemically-Induced Disorders; Mental Disorders
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0034935 BXGD002497 Babinski Reflex
C0035258 BXGD002523 Restless Legs Syndrome Nervous System Diseases; Mental Disorders
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037019 BXGD002658 Shy-Drager Syndrome Nervous System Diseases; Cardiovascular Diseases
C0037061 BXGD002664 Siderosis Respiratory Tract Diseases; Occupational Diseases
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037763 BXGD002699 Spasm Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037773 BXGD002704 Spastic Paraplegia, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0038273 BXGD002743 Stereotypic Movement Disorder Mental Disorders
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038522 BXGD002767 Subacute Sclerosing Panencephalitis Infections; Nervous System Diseases
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0039263 BXGD002805 Takayasu Arteritis Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0039483 BXGD002813 Giant Cell Arteritis Skin and Connective Tissue Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0040517 BXGD002872 Gilles de la Tourette syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042345 BXGD002977 Varicosity Cardiovascular Diseases
C0042384 BXGD002979 Vasculitis Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0043124 BXGD003031 West Nile Fever Infections; Nervous System Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079772 BXGD003099 T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085078 BXGD003118 Lysosomal Storage Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0085084 BXGD003121 Motor Neuron Disease Nervous System Diseases
C0085220 BXGD003142 Cerebral Amyloid Angiopathy Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0085606 BXGD003201 Urgency of micturition Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085623 BXGD003210 Akinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0085631 BXGD003214 Agitation Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0085632 BXGD003215 Apathy Behavior and Behavior Mechanisms
C0085762 BXGD003251 Alcohol abuse Chemically-Induced Disorders; Mental Disorders
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0086439 BXGD003284 Hypokinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0086647 BXGD003298 Mucopolysaccharidosis Type IIIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0086769 BXGD003310 Panic Attacks Mental Disorders
C0087012 BXGD003318 Ataxia, Spinocerebellar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0149521 BXGD003328 Pancreatitis, Chronic Digestive System Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0150080 BXGD003402 Social Communication Disorder Mental Disorders
C0151491 BXGD003428 Congenital musculoskeletal anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151889 BXGD003498 Hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0152020 BXGD003519 Gastroparesis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0152459 BXGD003600 Linear atrophy Pathological Conditions, Signs and Symptoms
C0154536 BXGD003719 Amphetamine or related acting sympathomimetic abuse Chemically-Induced Disorders; Mental Disorders
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0205969 BXGD004143 Thymic Carcinoma Neoplasms; Hemic and Lymphatic Diseases
C0206139 BXGD004159 Lichen Planus, Oral Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0206664 BXGD004226 Teratocarcinoma Neoplasms
C0221163 BXGD004395 Motor Disorders Mental Disorders
C0221505 BXGD004466 Lesion of brain
C0231688 BXGD004510 Gait, Shuffling Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0232197 BXGD004536 Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233565 BXGD004590 Bradykinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0233763 BXGD004611 Hallucinations, Visual Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234376 BXGD004659 Action Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234379 BXGD004662 Resting Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0235031 BXGD004714 Neurologic Symptoms Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235480 BXGD004751 Paroxysmal atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0236663 BXGD004817 Alcohol withdrawal syndrome Chemically-Induced Disorders; Mental Disorders
C0236733 BXGD004822 Amphetamine-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0236734 BXGD004823 Caffeine related disorders
C0236736 BXGD004825 Cocaine-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0236804 BXGD004835 Amphetamine Addiction Chemically-Induced Disorders; Mental Disorders
C0236807 BXGD004836 Amphetamine Abuse Chemically-Induced Disorders; Mental Disorders
C0240341 BXGD005032 Micrographia
C0240735 BXGD005052 Personality Change Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0242423 BXGD005164 Ramsay Hunt Paralysis Syndrome Nervous System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262405 BXGD005237 Cerebral dysfunction Nervous System Diseases
C0262424 BXGD005240 CNS DEGENERATION Nervous System Diseases
C0262584 BXGD005256 Carcinoma, Small Cell Neoplasms
C0262630 BXGD005262 Reduced concentration span Behavior and Behavior Mechanisms
C0268250 BXGD005868 Gaucher Disease, Type 2 (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268251 BXGD005869 Gaucher Disease, Type 3 (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268407 BXGD005936 Senile cardiac amyloidosis Nutritional and Metabolic Diseases; Cardiovascular Diseases
C0270715 BXGD006089 Degenerative Diseases, Central Nervous System Nervous System Diseases
C0270724 BXGD006092 Infantile Neuroaxonal Dystrophy Nervous System Diseases
C0270726 BXGD006093 Alexander Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0270733 BXGD006095 Striatonigral Degeneration Nervous System Diseases
C0270736 BXGD006096 Essential Tremor Nervous System Diseases
C0276496 BXGD006426 Familial Alzheimer Disease (FAD) Nervous System Diseases; Mental Disorders
C0278097 BXGD006496 Abnormal male sexual function
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278650 BXGD006553 Childhood Supratentorial Ependymoma Neoplasms
C0278678 BXGD006556 Metastatic Renal Cell Cancer
C0278874 BXGD006605 Adult Ependymoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282193 BXGD006798 Iron Overload Nutritional and Metabolic Diseases
C0333463 BXGD006954 Senile Plaques Pathological Conditions, Signs and Symptoms
C0334070 BXGD006986 Maturation defect
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0338455 BXGD007177 Dementia of frontal lobe type Nervous System Diseases; Mental Disorders
C0338457 BXGD007178 Aphasia, Progressive Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0338460 BXGD007179 Argyrophilic grain disease
C0338473 BXGD007182 Neuroaxonal Dystrophies Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0342776 BXGD007546 Nicotinamide adenine dinucleotide coenzyme Q reductase deficiency
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0349081 BXGD007889 Dementia in Parkinson's disease
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0393570 BXGD008093 Corticobasal degeneration Nervous System Diseases
C0393571 BXGD008094 Multiple System Atrophy Nervous System Diseases
C0393911 BXGD008155 Pure Autonomic Failure Nervous System Diseases
C0401149 BXGD008273 Chronic constipation Pathological Conditions, Signs and Symptoms
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0426980 BXGD008599 Motor symptoms
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0524662 BXGD009238 Opiate Addiction Chemically-Induced Disorders; Mental Disorders
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0525041 BXGD009254 Neurobehavioral Manifestations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0546983 BXGD009353 Post-Concussion Syndrome Nervous System Diseases; Wounds and Injuries
C0548883 BXGD009356 Low frustration tolerance Behavior and Behavior Mechanisms
C0564567 BXGD009486 Impulsive character (finding)
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0599458 BXGD009676 glycosphingolipidoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600427 BXGD009706 Cocaine Dependence Chemically-Induced Disorders; Mental Disorders
C0677050 BXGD009714 Manganese Poisoning Nervous System Diseases; Chemically-Induced Disorders
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0679407 BXGD009772 Gastrointestinal dysfunction Digestive System Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0700201 BXGD009880 Dyssomnias Nervous System Diseases; Mental Disorders
C0729555 BXGD009930 Infection of digestive system Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Infections
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0740858 BXGD010012 Substance abuse problem Chemically-Induced Disorders; Mental Disorders
C0744620 BXGD010103 Metastatic Head and Neck Squamous Cell Carcinoma Neoplasms
C0748903 BXGD010206 spinal cord involvement
C0751071 BXGD010311 Familial Dementia Nervous System Diseases; Mental Disorders
C0751072 BXGD010312 Frontotemporal Lobar Degeneration Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0751295 BXGD010383 Memory Loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0751733 BXGD010569 Degenerative Diseases, Spinal Cord Nervous System Diseases
C0751772 BXGD010583 REM Sleep Behavior Disorder Nervous System Diseases; Mental Disorders
C0751781 BXGD010590 Dentatorubral-Pallidoluysian Atrophy Nervous System Diseases
C0751783 BXGD010592 Lafora Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0751967 BXGD010657 Multiple Sclerosis, Relapsing-Remitting Immune System Diseases; Nervous System Diseases
C0752097 BXGD010659 Autosomal Dominant Juvenile Parkinson Disease Nervous System Diseases
C0752098 BXGD010660 Autosomal Dominant Parkinsonism Nervous System Diseases
C0752100 BXGD010661 Autosomal Recessive Parkinsonism Nervous System Diseases
C0752101 BXGD010662 Parkinsonism, Experimental Nervous System Diseases
C0752104 BXGD010663 Familial Juvenile Parkinsonism Nervous System Diseases
C0752105 BXGD010664 Parkinsonism, Juvenile Nervous System Diseases
C0752347 BXGD010721 Lewy Body Disease Nervous System Diseases; Mental Disorders
C0796611 BXGD010835 Newly Diagnosed Childhood Ependymoma Neoplasms
C0813217 BXGD010854 Expressionless face Nervous System Diseases
C0850703 BXGD010905 Frequent falls Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0860603 BXGD011236 Anxiety symptoms
C0865474 BXGD011290 Parkinsonism or Parkinson's disease NOS
C0865475 BXGD011291 Idiopathic Parkinsonism or Parkinson's disease
C0865476 BXGD011292 Primary Parkinsonism or Parkinson's disease
C0877008 BXGD011325 Enzyme inhibition disorder
C0917801 BXGD011412 Sleeplessness Nervous System Diseases; Mental Disorders
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0947785 BXGD011495 [D]Sleep disturbances (& [hypersomnia] or [insomnia])
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1096184 BXGD011607 West Nile viral infection Infections; Nervous System Diseases
C1112261 BXGD011656 Gaze palsy
C1112442 BXGD011668 Female sexual dysfunction
C1112443 BXGD011669 Male sexual dysfunction
C1134719 BXGD011688 Invasive Ductal Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1136033 BXGD011703 Cutaneous Mastocytosis Neoplasms; Skin and Connective Tissue Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1145628 BXGD011763 Autonomic nervous system disorders Nervous System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1261473 BXGD011855 Sarcoma Neoplasms
C1262477 BXGD011882 Weight decreased Pathological Conditions, Signs and Symptoms
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1270972 BXGD012006 Mild cognitive disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1321329 BXGD012430 Slowed saccades
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1333064 BXGD012587 Classical Hodgkin's Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1399358 BXGD013005 Hemiparkinsonism
C1456784 BXGD013124 Paranoia Mental Disorders
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C1527352 BXGD013278 Hepatic Form of Wilson Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1535950 BXGD013325 Gastrointestinal inflammation
C1609538 BXGD013444 Latent Tuberculosis Infections
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1695782 BXGD013498 Cerebral hypoperfusion
C1836150 BXGD014082 Gait imbalance
C1836904 BXGD014176 Spastic/hyperactive bladder
C1838681 BXGD014337 Rapidly progressive
C1842937 BXGD014546 AURAL ATRESIA, CONGENITAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1842981 BXGD014547 NEUROTICISM Behavior and Behavior Mechanisms
C1843013 BXGD014549 Alzheimer disease, familial, type 3 Nervous System Diseases; Mental Disorders
C1843792 BXGD014606 FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED
C1843921 BXGD014620 Postural instability Nervous System Diseases
C1846865 BXGD014845 Substantia nigra gliosis Pathological Conditions, Signs and Symptoms
C1846868 BXGD014846 Parkinsonism with favorable response to dopaminergic medication Nervous System Diseases
C1847640 BXGD014879 KUFOR-RAKEB SYNDROME Nervous System Diseases
C1850100 BXGD015108 PARKINSON DISEASE 15, AUTOSOMAL RECESSIVE (disorder) Eye Diseases; Nervous System Diseases
C1850442 BXGD015144 CEROID LIPOFUSCINOSIS, NEURONAL, 5 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C1851584 BXGD015221 Childhood Ependymoma Neoplasms
C1851958 BXGD015250 Lewy Body Variant of Alzheimer Disease Nervous System Diseases; Mental Disorders
C1851959 BXGD015251 Fluctuations in consciousness
C1852467 BXGD015283 Creutzfeldt-Jakob Disease, Sporadic Infections; Nervous System Diseases; Mental Disorders
C1853445 BXGD015337 PARKINSON DISEASE 7, AUTOSOMAL RECESSIVE EARLY-ONSET Nervous System Diseases
C1853833 BXGD015363 Parkinson Disease 6, Autosomal Recessive Early-Onset Nervous System Diseases
C1854182 BXGD015388 PARKINSON DISEASE 4, AUTOSOMAL DOMINANT LEWY BODY (disorder) Nervous System Diseases; Mental Disorders
C1862382 BXGD016125 SVEINSSON CHORIORETINAL ATROPHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1868528 BXGD016503 Orthostatic hypotension due to autonomic dysfunction Nervous System Diseases; Cardiovascular Diseases
C1868594 BXGD016511 Perry Syndrome Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Nervous System Diseases; Behavior and Behavior Mechanisms
C1868595 BXGD016512 PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
C1868596 BXGD016513 Atypical Parkinson Disease Nervous System Diseases
C1868675 BXGD016520 PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE Nervous System Diseases
C1961835 BXGD016676 Gaucher Disease, Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C1963060 BXGD016679 Agitation, CTCAE 3.0
C1969363 BXGD016773 Middle age onset
C2220255 BXGD016956 Motor disturbances
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2267227 BXGD017015 Bulimia Nervosa Mental Disorders
C2364082 BXGD017123 Sense of smell impaired Nervous System Diseases
C2609259 BXGD017173 Symphysis Pubis Dysfunction Pathological Conditions, Signs and Symptoms
C2712971 BXGD017492 Enteritis due to Norovirus Infections
C2718001 BXGD017521 Protein Misfolding Disorders Nutritional and Metabolic Diseases
C2718017 BXGD017522 TDP-43 Proteinopathies Nutritional and Metabolic Diseases; Nervous System Diseases
C2748208 BXGD017586 Executive dysfunction
C2750737 BXGD017675 DIARRHEA 5, WITH TUFTING ENTEROPATHY, CONGENITAL Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Nutritional and Metabolic Diseases
C2751492 BXGD017718 AMYLOIDOSIS, HEREDITARY, TRANSTHYRETIN-RELATED Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C2826323 BXGD017790 Refractory Cytopenia of Childhood
C2900450 BXGD017854 Other Creutzfeldt-Jakob disease Infections; Nervous System Diseases; Mental Disorders
C2936349 BXGD018109 Plaque, Amyloid Pathological Conditions, Signs and Symptoms
C2985280 BXGD018223 Blood Protein Measurement
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C3179455 BXGD018552 Niemann-Pick Disease, Type C1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3276706 BXGD018694 Small Fiber Neuropathy Nervous System Diseases
C3489791 BXGD018949 Parkinson Disease, Familial, Type 1 Nervous System Diseases
C3494358 BXGD018961 Prodromal Symptoms Pathological Conditions, Signs and Symptoms
C3534585 BXGD019063 Infection caused by Norovirus Infections
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3805043 BXGD019457 Vascular cognitive impairment
C3811918 BXGD019664 GRN-related frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C3825201 BXGD019684 Mitochondrial pathology
C3887938 BXGD019929 Deuteranomaly Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3888102 BXGD019952 Frontotemporal Dementia With Motor Neuron Disease Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C4020732 BXGD020474 Mitochondrial abnormalities
C4048158 BXGD021890 Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4082764 BXGD022093 Gastrointestinal infection Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Infections
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4274355 BXGD022352 Autosomal dominant late onset Parkinson disease Nervous System Diseases
C4275179 BXGD022368 Young onset Parkinson disease Nervous System Diseases
C4285693 BXGD022446 HIV-associated neurocognitive disorder Infections; Immune System Diseases
C4285807 BXGD022455 Behavioral and psychological symptoms of dementia
C4302185 BXGD022525 Atypical Parkinsonism Nervous System Diseases
C4477086 BXGD022919 Cotton wool plaques Pathological Conditions, Signs and Symptoms
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
C4524839 BXGD023111 Recurrent Head and Neck Squamous Cell Carcinoma Neoplasms
C4524856 BXGD023113 Refractory Classic Hodgkin Lymphoma
C4531121 BXGD023189 Monotonic speech
C4551583 BXGD023361 Cerebral cortical atrophy
C4551584 BXGD023362 Brain atrophy Nervous System Diseases
C4551683 BXGD023389 Adrenal Gland Pheochromocytoma Neoplasms; Endocrine System Diseases
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4551993 BXGD023469 Amyotrophic Lateral Sclerosis, Familial Nutritional and Metabolic Diseases; Nervous System Diseases
C4552855 BXGD023528 Agitation, CTCAE 5.0
C4553743 BXGD023548 Spasticity, CTCAE
C4553976 BXGD023554 Urinary Urgency, CTCAE 5
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721698 BXGD023763 Metastatic Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4721772 BXGD023767 Postoperative delirium Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4727069 BXGD023850 Advanced Renal Cell Carcinoma
C4732730 BXGD023895 Blood spots
C4744564 BXGD023947 Metastatic Colorectal Carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000194 Sanguinarine 332.33
BXGC0000430 Gossypol 518.55
BXGC0001076 4-Hydroxyderricin 338.4
BXGC0001079 Xanthoangelol 392.49
BXGC0001082 Xanthosine 284.23
BXGC0001091 Allantoin 158.12
BXGC0001767 (E)-Resveratrol 228.25
BXGC0002616 Copper 63.55
BXGC0002801 Phellopterin 300.31
BXGC0002906 Caffeic acid ester 284.31
BXGC0002993 2-Methylquinoline 175.25
BXGC0003066 Phenols 199.27
BXGC0003221 Xanthyletin 228.24
BXGC0003707 Estrogen 268.36
BXGC0003894 Phospholipase 343.36
BXGC0004275 Acetaldehyde 44.05
BXGC0004322 xi-3-Hydroxy-5-phenylpentanoic acid O-beta-D-Glucopyranoside 356.37
BXGC0004969 1,4,5-Naphthalenetriol 176.17
BXGC0005017 4,7-Dihydroxy-2H-1-benzopyran-2-one 178.14
BXGC0005645 Quinoline 129.16
BXGC0005846 Oroselone 226.23
BXGC0005981 (S)-4',5,7-Trihydroxy-8-prenylflavanone 340.38
BXGC0005982 Curcumin 368.38
BXGC0006422 Mercenene 214.05
BXGC0007530 Folic acid 441.4
BXGC0008168 7-Methylchrysin 268.26
BXGC0008181 Morusin 420.45
BXGC0008707 Isoliquiritigenin 256.25
BXGC0009984 Pyrafoline D 347.45
BXGC0009993 (R)-Mahanine 347.45
BXGC0011207 (R)-Bitalin A 218.25
BXGC0012496 13-epi-sclareol 308.27
BXGC0013582 Curcumin 368.13
BXGC0014947 Glabridin 324.14
BXGC0015314 1-(2,6-Dihydroxyphenyl)Dodecan-1-One 292.2
BXGC0015879 Chlorhexidine 504.2
BXGC0016915 pterosin S 250.12
BXGC0017701 Altenusin 290.08
BXGC0018032 2-Hydroxychalcone 224.08
BXGC0019117 Tannic Acid 1700.17
BXGC0019273 Glabrol 392.2
BXGC0021255 4-[(3S)-8,8-Dimethyl-3,4-Dihydro-2H-Pyrano[2,3-F]Chromen-3-Yl]Benzene-1,3-Diol 324.14
BXGC0021836 Honokiol 266.13
BXGC0022169 2-[(1S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-Dihydroxyphenyl)-3-Methylcyclohex-2-En-1-Yl]-1,3,5A,8-Tetrahydroxy-10A-(3-Methylbut-2-Enyl)-[1]Benzofuro[3,2-B]Chromen-11-One 708.22
BXGC0022231 Ursodiol 392.29
BXGC0024489 Licarin A 326.15
BXGC0024813 Demethoxycurcumin 338.12
BXGC0025757 Calcimycin 523.27
BXGC0026935 Triclosan 287.95
BXGC0027063 Rocaglamide 505.21
BXGC0027421 Paclitaxel 853.33
BXGC0027639 sanggenon A 436.15
BXGC0028001 Beta-Lapachone 242.09
BXGC0028710 Kokusaginine 259.08
BXGC0029089 Phenazine-1-Carboxylic Acid 224.06
BXGC0029205 Sphaeropsidin A 346.18
BXGC0029585 Biochanin A, Dimethyl Ether 312.1
BXGC0029721 Sclerotiorin 390.12
BXGC0030164 cudraxanthone H 380.16
BXGC0030696 2,3-Dimethoxyxanthen-9-One 256.07
BXGC0030879 Mesodihydroguaiaretic Acid 330.18
BXGC0031002 Diffractaic Acid 374.14
BXGC0031067 6,7-Dimethoxy-3H-2-Benzofuran-1-One 194.06
BXGC0032634 Chlorothalonil 263.88
BXGC0033365 Gardenin 418.13
BXGC0033776 Cycloheximide 281.16
BXGC0034968 Dienestrol 266.13
BXGC0037407 Lithocholic Acid 376.3
BXGC0037722 Pomiferin 420.16
BXGC0038197 2-Methoxyphenazine 210.08
BXGC0038316 Cholesterol 386.35
BXGC0038486 (2S)-3-[(2S,3S)-5,7-Dihydroxy-2-(4-Methoxyphenyl)-4-Oxo-2,3-Dihydrochromen-3-Yl]-5,7-Dihydroxy-2-(4-Methoxyphenyl)-2,3-Dihydrochromen-4-One 570.15
BXGC0038977 barbatic acid 360.12
BXGC0039172 Oxyresveratrol 244.07
BXGC0039281 Methyl (1S,4As,5As,6R,10As)-1-Methyl-2'-Oxospiro[1,4A,5,5A,7,8,10,10A-Octahydropyrano[3,4-F]Indolizine-6,3'-1H-Indole]-4-Carboxylate 368.17
BXGC0040949 Hydroxyprogesterone Caproate 428.29
BXGC0041560 Thiram 239.99
BXGC0042091 Dequalinium 456.33
BXGC0042105 Verrucarin A 502.22
BXGC0042127 Oxyquinoline 145.05
BXGC0042129 (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-Methylbut-3-En-2-Yloxy)Oxane-3,4,5-Triol 248.13
BXGC0042659 E968 122.06
BXGC0043398 Glyasperin D 370.18
BXGC0046510 Tpck 351.07
BXGC0047086 4-[(2R)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]Piperidine-2,6-Dione 281.16
BXGC0050880 Cudraflavone B 420.16
BXGC0053078 Pinosylvin Methyl Ether 226.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein