adisease

Showing entry for Low Back Pain

General Disease Information
BXGD Id	BXGD001727
Disease Name	Low Back Pain
Disease CUI Id	C0024031
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0025142 HP:0000924
Human Phenotype Ontology Term	Constitutional symptom; Abnormality of the skeletal system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O75173	BXGT005105	A disintegrin and metalloproteinase with thrombospondin motifs 4	9507	reviewed	Enzyme
O95405	BXGT005379	Zinc finger FYVE domain-containing protein 9	9372	reviewed
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P09958	BXGT006950	Furin	5045	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P30536	BXGT009435	Translocator protein	706	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P42226	BXGT010288	Signal transducer and activator of transcription 6	6778	reviewed	Nucleic acid binding
P43026	BXGT010351	Growth/differentiation factor 5	8200	reviewed	Signaling
P52788	BXGT010953	Spermine synthase	6611	reviewed
P54886	BXGT011092	Delta-1-pyrroline-5-carboxylate synthase	5832	reviewed	Enzyme
P55211	BXGT011111	Caspase-9	842	reviewed	Enzyme
Q8WWA0	BXGT018999	Intelectin-1	55600	reviewed
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UNA0	BXGT021784	A disintegrin and metalloproteinase with thrombospondin motifs 5	11096	reviewed	Enzyme
Q9UBP0	BXGT023601	Spastin	6683	reviewed	Cellular structure

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}