adisease

Showing entry for Macular degeneration

General Disease Information
BXGD Id	BXGD001772
Disease Name	Macular degeneration
Disease CUI Id	C0024437
MeSH Codes	C23 C11 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000478
Human Phenotype Ontology Term	Abnormality of the eye
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P20839	BXGT008608	Inosine-5'-monophosphate dehydrogenase 1	3614	reviewed	Enzyme
P22352	BXGT008758	Glutathione peroxidase 3	2878	reviewed	Enzyme
P36955	BXGT009946	Pigment epithelium-derived factor	5176	reviewed	Enzyme modulator
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P49638	BXGT010720	Alpha-tocopherol transfer protein	7274	reviewed	Transporter
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	1859	reviewed	Kinase
Q8WWY3	BXGT019006	U4/U6 small nuclear ribonucleoprotein Prp31	26121	reviewed	Nucleic acid binding
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q92834	BXGT019381	X-linked retinitis pigmentosa GTPase regulator	6103	reviewed
Q96AT9	BXGT019619	Ribulose-phosphate 3-epimerase	6120	reviewed
Q9BUF5	BXGT020135	Tubulin beta-6 chain	84617	reviewed	Cellular structure
Q9BXJ0	BXGT020169	Complement C1q tumor necrosis factor-related protein 5	114902	reviewed
Q9Y4W6	BXGT025025	AFG3-like protein 2	10939	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}