adisease

Showing entry for Sandhoff Disease

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD002580
Disease Name	Sandhoff Disease
Disease CUI Id	C0036161
MeSH Codes	C16 C18 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0014667 DOID:630
Disease Ontology Class Name	disease of metabolism; genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P06865	BXGT006516	Beta-hexosaminidase subunit alpha	3073	reviewed	Enzyme
P07686	BXGT006657	Beta-hexosaminidase subunit beta	3074	reviewed	Enzyme
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P0CG48	BXGT007468	Polyubiquitin-C	7316	reviewed	Nucleic acid binding
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P17900	BXGT008353	Ganglioside GM2 activator	2760	reviewed	Transporter
P40933	BXGT010209	Interleukin-15	3600	reviewed
P62979	BXGT011476	Ubiquitin-40S ribosomal protein S27a	6233	reviewed	Nucleic acid binding
Q16739	BXGT013663	Ceramide glucosyltransferase	7357	reviewed	Enzyme
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
P61916	BXGT025881	NPC intracellular cholesterol transporter 2	10577	reviewed
Q15818	BXGT026007	Neuronal pentraxin-1	4884	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}