adisease

Showing entry for Tay-Sachs Disease

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD002809
Disease Name	Tay-Sachs Disease
Disease CUI Id	C0039373
MeSH Codes	C16 C18 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0014667 DOID:630
Disease Ontology Class Name	disease of metabolism; genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P06865	BXGT006516	Beta-hexosaminidase subunit alpha	3073	reviewed	Enzyme
P07686	BXGT006657	Beta-hexosaminidase subunit beta	3074	reviewed	Enzyme
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P17900	BXGT008353	Ganglioside GM2 activator	2760	reviewed	Transporter
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35858	BXGT009876	Insulin-like growth factor-binding protein complex acid labile subunit	3483	reviewed	Receptor
P45381	BXGT010460	Aspartoacylase	443	reviewed
P55899	BXGT011131	IgG receptor FcRn large subunit p51	2217	reviewed
Q9UQ49	BXGT021805	Sialidase-3	10825	reviewed	Enzyme
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
Q15818	BXGT026007	Neuronal pentraxin-1	4884	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}