adisease

Showing entry for Erythropoietic Protoporphyria

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD003959
Disease Name	Erythropoietic Protoporphyria
Disease CUI Id	C0162568
MeSH Codes	C16 C06 C18 C17
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0014667 DOID:630 DOID:7
Disease Ontology Class Name	disease of metabolism; genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O43557	BXGT004600	Tumor necrosis factor ligand superfamily member 14	8740	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P08397	BXGT006768	Porphobilinogen deaminase	3145	reviewed	Enzyme
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10599	BXGT007583	Thioredoxin	7295	reviewed
P13196	BXGT007886	5-aminolevulinate synthase, nonspecific, mitochondrial	211	reviewed	Enzyme
P22557	BXGT008783	5-aminolevulinate synthase, erythroid-specific, mitochondrial	212	reviewed	Enzyme
P22830	BXGT008809	Ferrochelatase, mitochondrial	2235	reviewed	Enzyme
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P50336	BXGT010791	Protoporphyrinogen oxidase	5498	reviewed
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P81172	BXGT011935	Hepcidin	57817	reviewed
Q16881	BXGT013688	Thioredoxin reductase 1, cytoplasmic	7296	reviewed	Enzyme
Q5JAM2	BXGT015430	5-aminolevulinate synthase	211	unreviewed
Q9P2R7	BXGT021304	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	8803	reviewed	Enzyme
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}