adisease

Showing entry for Atrioventricular Septal Defect

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD012963
Disease Name	Atrioventricular Septal Defect
Disease CUI Id	C1389018
MeSH Codes	C16 C14
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
Semantic Type	Congenital Abnormality
Human Phenotype Ontology Id	HP:0001626
Human Phenotype Ontology Term	Abnormality of the cardiovascular system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15151	BXGT004132	Protein Mdm4	4194	reviewed	Nucleic acid binding
O95644	BXGT005389	Nuclear factor of activated T-cells, cytoplasmic 1	4772	reviewed	Transcription factor
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P41161	BXGT010229	ETS translocation variant 5	2119	reviewed	Transcription factor
P41440	BXGT010261	Folate transporter 1	6573	reviewed	Transporter
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
Q04771	BXGT012783	Activin receptor type-1	90	reviewed	Kinase
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q99593	BXGT019939	T-box transcription factor TBX5	6910	reviewed	Transcription factor
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9UHX1	BXGT021707	Poly(U)-binding-splicing factor PUF60	22827	reviewed
Q9UIF8	BXGT021718	Bromodomain adjacent to zinc finger domain protein 2B	29994	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}