adisease

Showing entry for Alport Syndrome

General Disease Information
BXGD Id	BXGD013414
Disease Name	Alport Syndrome
Disease CUI Id	C1567741
MeSH Codes	C16 C13 C17 C12
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630
Disease Ontology Class Name	genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15230	BXGT004138	Laminin subunit alpha-5	3911	reviewed	Enzyme modulator
O60488	BXGT004878	Long-chain-fatty-acid--CoA ligase 4	2182	reviewed	Enzyme
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P27037	BXGT009153	Activin receptor type-2A	92	reviewed	Kinase
P29400	BXGT009343	Collagen alpha-5(IV) chain	1287	reviewed
P30533	BXGT009434	Alpha-2-macroglobulin receptor-associated protein	4043	reviewed
P35579	BXGT009852	Myosin-9	4627	reviewed
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P51795	BXGT010891	H(+)/Cl(-) exchange transporter 5	1184	reviewed	Ion channel
P55899	BXGT011131	IgG receptor FcRn large subunit p51	2217	reviewed
Q07973	BXGT012952	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	1591	reviewed	Enzyme
Q08345	BXGT012982	Epithelial discoidin domain-containing receptor 1	780	reviewed	Kinase
Q96D53	BXGT019637	Atypical kinase COQ8B, mitochondrial	79934	reviewed	Kinase
Q99653	BXGT019945	Calcineurin B homologous protein 1	11261	reviewed
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9P2W7	BXGT021306	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	27087	reviewed	Enzyme
Q9Y4K0	BXGT022280	Lysyl oxidase homolog 2	4017	reviewed
Q01955	BXGT023255	Collagen alpha-3(IV) chain	1285	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}