Showing entry for Calcineurin B homologous protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019945
Protein NameCalcineurin B homologous protein 1
Uniport IdQ99653
GeneCHP1
Gene Id11261
DomainEF-hand_7
Pfam PF13499  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0017156 calcium-ion regulated exocytosis
Biological Process GO:0071468 cellular response to acidic pH
Biological Process GO:0031122 cytoplasmic microtubule organization
Biological Process GO:0030214 hyaluronan catabolic process
Biological Process GO:0022406 membrane docking
Biological Process GO:0061025 membrane fusion
Biological Process GO:0061024 membrane organization
Biological Process GO:0001578 microtubule bundle formation
Biological Process GO:0070885 negative regulation of calcineurin-NFAT signaling cascade
Biological Process GO:0032088 negative regulation of NF-kappaB transcription factor activity
Biological Process GO:0010923 negative regulation of phosphatase activity
Biological Process GO:0031953 negative regulation of protein autophosphorylation
Biological Process GO:0042308 negative regulation of protein import into nucleus
Biological Process GO:0006469 negative regulation of protein kinase activity
Biological Process GO:0001933 negative regulation of protein phosphorylation
Biological Process GO:0031397 negative regulation of protein ubiquitination
Biological Process GO:0060050 positive regulation of protein glycosylation
Biological Process GO:0090314 positive regulation of protein targeting to membrane
Biological Process GO:0051222 positive regulation of protein transport
Biological Process GO:0032417 positive regulation of sodium:proton antiporter activity
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0051259 protein complex oligomerization
Biological Process GO:0006611 protein export from nucleus
Biological Process GO:0050821 protein stabilization
Biological Process GO:0051453 regulation of intracellular pH
Biological Process GO:1901214 regulation of neuron death
Biological Process GO:0007264 small GTPase mediated signal transduction
molecular function GO:0048306 calcium-dependent protein binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0019900 kinase binding
molecular function GO:0008017 microtubule binding
molecular function GO:0015459 potassium channel regulator activity
molecular function GO:0004860 protein kinase inhibitor activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
cellular component GO:0070062 extracellular exosome
cellular component GO:0005925 focal adhesion
cellular component GO:0000139 Golgi membrane
cellular component GO:0015630 microtubule cytoskeleton
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0030133 transport vesicle
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1630316 Glycosaminoglycan metabolism
R-HSA-2142845 Hyaluronan metabolism
R-HSA-2160916 Hyaluronan uptake and degradation
R-HSA-71387 Metabolism of carbohydrates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001175 BXGD000029 Acquired Immunodeficiency Syndrome Infections; Immune System Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005411 BXGD000313 Biliary Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0005956 BXGD000356 Bone Marrow Diseases Hemic and Lymphatic Diseases
C0006023 BXGD000362 Borna Disease Infections; Animal Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007140 BXGD000447 Carcinosarcoma Neoplasms
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0008354 BXGD000533 Cholera Infections
C0008495 BXGD000548 Chorioamnionitis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011226 BXGD000704 Hepatitis D Infection Digestive System Diseases; Infections
C0011311 BXGD000714 Dengue Fever Infections
C0014740 BXGD000944 Erythema Chronicum Migrans Infections; Skin and Connective Tissue Diseases
C0015674 BXGD001012 Chronic Fatigue Syndrome Infections; Musculoskeletal Diseases; Nervous System Diseases
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0017668 BXGD001143 Focal glomerulosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0017677 BXGD001147 Glossitis, Benign Migratory Stomatognathic Diseases
C0018203 BXGD001184 Chronic granulomatous disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022638 BXGD001567 Ketosis Nutritional and Metabolic Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022680 BXGD001576 Polycystic Kidney Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023524 BXGD001681 Leukoencephalopathy, Progressive Multifocal Infections; Nervous System Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024198 BXGD001743 Lyme Disease Infections
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024302 BXGD001760 Reticulosarcoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0026918 BXGD001948 Mycobacterium Infections Infections
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029118 BXGD002111 Opportunistic Infections Infections
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029423 BXGD002143 Cartilaginous exostosis Neoplasms; Musculoskeletal Diseases
C0030481 BXGD002228 Tropical Spastic Paraparesis Infections; Nervous System Diseases
C0030499 BXGD002232 Parasitic Diseases Infections
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0034935 BXGD002497 Babinski Reflex
C0035372 BXGD002544 Rett Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0036323 BXGD002595 Schistosomiasis Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037928 BXGD002713 Spinal Cord Diseases Nervous System Diseases
C0038826 BXGD002779 Superinfection Infections
C0039128 BXGD002794 Syphilis Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0039273 BXGD002806 Talipes cavus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0040558 BXGD002873 Toxoplasmosis Infections
C0041296 BXGD002903 Tuberculosis Infections
C0042109 BXGD002957 Urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0042749 BXGD002998 Viremia Pathological Conditions, Signs and Symptoms; Infections
C0042769 BXGD002999 Virus Diseases Infections
C0042834 BXGD003004 Vital capacity
C0079774 BXGD003101 Peripheral T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0151889 BXGD003498 Hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0206019 BXGD004144 HIV Encephalopathy Infections; Immune System Diseases; Nervous System Diseases; Mental Disorders
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0206663 BXGD004225 Neuroectodermal Tumor, Primitive Neoplasms
C0221232 BXGD004413 Welts Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0234632 BXGD004691 Reduced visual acuity Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0235031 BXGD004714 Neurologic Symptoms Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0238462 BXGD004937 Medullary carcinoma of thyroid Neoplasms; Endocrine System Diseases
C0238790 BXGD004956 bone destruction
C0242381 BXGD005159 Lyme Arthritis Infections
C0242723 BXGD005193 Parasitemia Pathological Conditions, Signs and Symptoms; Infections
C0275518 BXGD006375 Acute infectious disease Pathological Conditions, Signs and Symptoms; Infections
C0276548 BXGD006430 HIV encephalitis Infections; Immune System Diseases; Nervous System Diseases; Mental Disorders
C0281710 BXGD006779 Childhood Large Cell Lymphoma
C0343751 BXGD007641 Asymptomatic human immunodeficiency virus infection Infections; Immune System Diseases
C0343752 BXGD007642 Acute HIV infection Infections; Immune System Diseases
C0349637 BXGD007942 Common acute lymphoblastic leukemia
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0427065 BXGD008604 Distal muscle weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0456070 BXGD008863 Growth delay
C0520463 BXGD009085 Chronic active hepatitis Digestive System Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0541764 BXGD009259 Delayed bone age
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0747256 BXGD010168 Parasitic infection Pathological Conditions, Signs and Symptoms; Infections
C0751265 BXGD010370 Learning Disabilities Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0752347 BXGD010721 Lewy Body Disease Nervous System Diseases; Mental Disorders
C0795825 BXGD010741 Chromosome 8, trisomy 8p Pathological Conditions, Signs and Symptoms
C0850703 BXGD010905 Frequent falls Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0850705 BXGD010906 Adult Acquired Toxoplasmosis Infections
C0853112 BXGD010967 Chronic infection with HIV
C0856169 BXGD011096 Endothelial dysfunction
C1136179 BXGD011712 Hammer Toe Musculoskeletal Diseases
C1142553 BXGD011761 Primary HIV infection Infections; Immune System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1321329 BXGD012430 Slowed saccades
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332216 BXGD012510 Adult Systemic Anaplastic Large Cell Lymphoma
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1336548 BXGD012850 Systemic Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1567435 BXGD013413 Polycystic Kidney - body part Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1567741 BXGD013414 Alport Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C1841984 BXGD014487 GLOMUVENOUS MALFORMATIONS Neoplasms
C1848736 BXGD014970 Distal amyotrophy
C1853743 BXGD015358 Muscular hypotonia of the trunk Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1858427 BXGD015791 Limited extraocular movements
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2363741 BXGD017100 HIV-1 infection
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4048305 BXGD021901 Neuroepithelioma
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4087436 BXGD022148 HIV viraemia Infections
C4520983 BXGD023052 Congenital atresia of extrahepatic bile duct Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C4553743 BXGD023548 Spasticity, CTCAE
C4733092 BXGD023907 estrogen receptor-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein