adisease

Showing entry for Decreased activity of mitochondrial complex I

General Disease Information
BXGD Id	BXGD017382
Disease Name	Decreased activity of mitochondrial complex I
Disease CUI Id	C2677650
MeSH Codes
Disease Class Name
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0001939 HP:0025354
Human Phenotype Ontology Term	Abnormality of metabolism/homeostasis; Abnormal cellular phenotype
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00217	BXGT003898	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	4728	reviewed	Enzyme
O15239	BXGT004139	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	4694	reviewed
O43181	BXGT004576	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	4724	reviewed
O43676	BXGT004611	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	4709	reviewed
O75251	BXGT005107	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	374291	reviewed
O75306	BXGT005108	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	4720	reviewed	Enzyme
O75380	BXGT005120	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	4726	reviewed	Enzyme
O75489	BXGT005131	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	4722	reviewed
O96000	BXGT005412	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10	4716	reviewed
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03891	BXGT006110	NADH-ubiquinone oxidoreductase chain 2	4536	reviewed
P03897	BXGT006111	NADH-ubiquinone oxidoreductase chain 3	4537	reviewed
P19404	BXGT008477	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	4729	reviewed
P28331	BXGT009252	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	4719	reviewed	Enzyme
P49821	BXGT010748	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	4723	reviewed
P56556	BXGT011179	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	4700	reviewed	Enzyme
Q5JPH6	BXGT015456	Probable glutamate--tRNA ligase, mitochondrial	124454	reviewed	Enzyme
Q86Y39	BXGT017632	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11	126328	reviewed
Q8N183	BXGT018497	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2	91942	reviewed
Q99757	BXGT019959	Thioredoxin, mitochondrial	25828	reviewed	Enzyme
Q9BU61	BXGT020131	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3	25915	reviewed
Q9HA77	BXGT020504	Probable cysteine--tRNA ligase, mitochondrial	79587	reviewed	Enzyme
Q9NX14	BXGT021242	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	54539	reviewed	Enzyme
Q9P032	BXGT021286	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4	29078	reviewed
Q9Y375	BXGT022253	Complex I intermediate-associated protein 30, mitochondrial	51103	reviewed
Q9Y6M9	BXGT022336	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9	4715	reviewed	Enzyme
Q9H1K1	BXGT025766	Iron-sulfur cluster assembly enzyme ISCU, mitochondrial	23479	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}