Showing entry for Gestational trophoblastic disease


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018040
Disease NameGestational trophoblastic disease
Disease CUI IdC2931618
MeSH Codes C04   C13  
Disease Class NameNeoplasms; Female Urogenital Diseases and Pregnancy Complications
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 10298 reviewed Kinase
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P06276 BXGT006430 Cholinesterase 590 reviewed
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P21673 BXGT008676 Diamine acetyltransferase 1 6303 reviewed
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 5058 reviewed Kinase
Q13177 BXGT013323 Serine/threonine-protein kinase PAK 2 5062 reviewed Kinase
Q13625 BXGT013384 Apoptosis-stimulating of p53 protein 2 7159 reviewed Enzyme modulator
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q2M1P5 BXGT014129 Kinesin-like protein KIF7 374654 reviewed
Q92743 BXGT019368 Serine protease HTRA1 5654 reviewed Enzyme
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UQF0 BXGT021812 Syncytin-1 30816 reviewed
P98082 BXGT025047 Disabled homolog 2 1601 reviewed Signaling
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease