Showing entry for Actin, cytoplasmic 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011512
Protein NameActin, cytoplasmic 2
Uniport IdP63261
GeneACTG1
Gene Id71
DomainActin
Pfam PF00022  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04015 Rap1 signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04145 Phagosome
4. Cellular Processes 4.2 Cell growth and death hsa04210 Apoptosis
3. Environmental Information Processing 3.2 Signal transduction hsa04390 Hippo signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04510 Focal adhesion
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04520 Adherens junction
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
5. Organismal Systems 5.1 Immune system hsa04611 Platelet activation
5. Organismal Systems 5.1 Immune system hsa04670 Leukocyte transendothelial migration
5. Organismal Systems 5.10 Environmental adaptation hsa04714 Thermogenesis
4. Cellular Processes 4.5 Cell motility hsa04810 Regulation of actin cytoskeleton
5. Organismal Systems 5.2 Endocrine system hsa04919 Thyroid hormone signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04921 Oxytocin signaling pathway
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05100 Bacterial invasion of epithelial cells
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05110 Vibrio cholerae infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05130 Pathogenic Escherichia coli infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05131 Shigellosis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05132 Salmonella infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05135 Yersinia infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05164 Influenza A
6. Human Diseases 6.1 Cancers: Overview hsa05205 Proteoglycans in cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05225 Hepatocellular carcinoma
6. Human Diseases 6.6 Cardiovascular diseases hsa05410 Hypertrophic cardiomyopathy (HCM)
6. Human Diseases 6.6 Cardiovascular diseases hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
6. Human Diseases 6.6 Cardiovascular diseases hsa05414 Dilated cardiomyopathy (DCM)
6. Human Diseases 6.6 Cardiovascular diseases hsa05416 Viral myocarditis
6. Human Diseases 6.6 Cardiovascular diseases hsa05418 Fluid shear stress and atherosclerosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001525 angiogenesis
Biological Process GO:0034329 cell junction assembly
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0048013 ephrin receptor signaling pathway
Biological Process GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:0035633 maintenance of blood-brain barrier
Biological Process GO:0061024 membrane organization
Biological Process GO:0001738 morphogenesis of a polarized epithelium
Biological Process GO:0070527 platelet aggregation
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0090303 positive regulation of wound healing
Biological Process GO:1902396 protein localization to bicellular tight junction
Biological Process GO:0051893 regulation of focal adhesion assembly
Biological Process GO:0051492 regulation of stress fiber assembly
Biological Process GO:0150111 regulation of transepithelial transport
Biological Process GO:0001895 retina homeostasis
Biological Process GO:0045214 sarcomere organization
Biological Process GO:0120192 tight junction assembly
molecular function GO:0005524 ATP binding
molecular function GO:0042802 identical protein binding
molecular function GO:0005522 profilin binding
molecular function GO:0005200 structural constituent of cytoskeleton
molecular function GO:0098973 structural constituent of postsynaptic actin cytoskeleton
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0005884 actin filament
cellular component GO:0043296 apical junction complex
cellular component GO:0120220 basal body patch
cellular component GO:0072562 blood microparticle
cellular component GO:0005911 cell-cell junction
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0097433 dense body
cellular component GO:0070062 extracellular exosome
cellular component GO:0005615 extracellular space
cellular component GO:0031941 filamentous actin
cellular component GO:0005925 focal adhesion
cellular component GO:0016020 membrane
cellular component GO:0030016 myofibril
cellular component GO:0005634 nucleus
cellular component GO:0045335 phagocytic vesicle
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1266738 Developmental Biology
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-1500931 Cell-Cell communication
R-HSA-1500931 Cell-Cell communication
R-HSA-157858 Gap junction trafficking and regulation
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-190828 Gap junction trafficking
R-HSA-190873 Gap junction degradation
R-HSA-194138 Signaling by VEGF
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194315 Signaling by Rho GTPases
R-HSA-195258 RHO GTPase Effectors
R-HSA-195258 RHO GTPase Effectors
R-HSA-196025 Formation of annular gap junctions
R-HSA-199991 Membrane Trafficking
R-HSA-199991 Membrane Trafficking
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-2682334 EPH-Ephrin signaling
R-HSA-373760 L1CAM interactions
R-HSA-373760 L1CAM interactions
R-HSA-3928662 EPHB-mediated forward signaling
R-HSA-3928665 EPH-ephrin mediated repulsion of cells
R-HSA-418990 Adherens junctions interactions
R-HSA-418990 Adherens junctions interactions
R-HSA-421270 Cell-cell junction organization
R-HSA-421270 Cell-cell junction organization
R-HSA-422475 Axon guidance
R-HSA-422475 Axon guidance
R-HSA-437239 Recycling pathway of L1
R-HSA-437239 Recycling pathway of L1
R-HSA-4420097 VEGFA-VEGFR2 Pathway
R-HSA-445095 Interaction between L1 and Ankyrins
R-HSA-445095 Interaction between L1 and Ankyrins
R-HSA-446353 Cell-extracellular matrix interactions
R-HSA-446728 Cell junction organization
R-HSA-446728 Cell junction organization
R-HSA-5626467 RHO GTPases activate IQGAPs
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-5663205 Infectious disease
R-HSA-5663205 Infectious disease
R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs
R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs
R-HSA-5663220 RHO GTPases Activate Formins
R-HSA-5663220 RHO GTPases Activate Formins
R-HSA-5673001 RAF/MAP kinase cascade
R-HSA-5674135 MAP2K and MAPK activation
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants
R-HSA-6802948 Signaling by high-kinase activity BRAF mutants
R-HSA-6802949 Signaling by RAS mutants
R-HSA-6802952 Signaling by BRAF and RAF fusions
R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF
R-HSA-6802957 Oncogenic MAPK signaling
R-HSA-8856828 Clathrin-mediated endocytosis
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9607240 FLT3 Signaling
R-HSA-9649948 Signaling downstream of RAS mutants
R-HSA-9656223 Signaling by RAF1 mutants
R-HSA-9658195 Leishmania infection
R-HSA-9658195 Leishmania infection
R-HSA-9664407 Parasite infection
R-HSA-9664407 Parasite infection
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9675108 Nervous system development
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001787 BXGD000076 Osteoporosis, Age-Related Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002875 BXGD000135 Cooley's anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003537 BXGD000208 Aphasia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007621 BXGD000468 Neoplastic Cell Transformation Pathological Conditions, Signs and Symptoms; Neoplasms
C0007787 BXGD000487 Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0007820 BXGD000491 Cerebrovascular Disorders Nervous System Diseases; Cardiovascular Diseases
C0007959 BXGD000507 Charcot-Marie-Tooth Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0009363 BXGD000599 Congenital ocular coloboma (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013264 BXGD000808 Muscular Dystrophy, Duchenne Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0013473 BXGD000845 Eating Disorders Mental Disorders
C0013528 BXGD000851 Echolalia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019100 BXGD001283 Severe Dengue Infections
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020295 BXGD001372 Hydronephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0023343 BXGD001635 Leprosy Infections
C0023418 BXGD001642 leukemia Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024433 BXGD001771 Macrostomia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0024530 BXGD001783 Malaria Infections
C0024535 BXGD001785 Malaria, Falciparum Infections
C0024537 BXGD001786 Malaria, Vivax Infections
C0024667 BXGD001794 Animal Mammary Neoplasms Neoplasms; Animal Diseases
C0024668 BXGD001795 Mammary Neoplasms, Experimental Neoplasms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026884 BXGD001945 Mutism Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029422 BXGD002142 Osteochondrodysplasias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0029429 BXGD002145 Osteochondrosis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029459 BXGD002159 Osteoporosis, Senile Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037090 BXGD002665 Signs and Symptoms, Respiratory Pathological Conditions, Signs and Symptoms
C0037856 BXGD002707 Spermatic Cord Torsion Male Urogenital Diseases
C0040264 BXGD002857 Tinnitus Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041327 BXGD002916 Tuberculosis, Pulmonary Infections; Respiratory Tract Diseases
C0042025 BXGD002950 Urinary Stress Incontinence Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042749 BXGD002998 Viremia Pathological Conditions, Signs and Symptoms; Infections
C0042769 BXGD002999 Virus Diseases Infections
C0042834 BXGD003004 Vital capacity
C0043167 BXGD003034 Pertussis Infections; Respiratory Tract Diseases
C0043168 BXGD003035 Whooping cough due to unspecified organism Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0149871 BXGD003375 Deep Vein Thrombosis Cardiovascular Diseases
C0150055 BXGD003401 Chronic pain Pathological Conditions, Signs and Symptoms
C0151313 BXGD003413 Sensory neuropathy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0152439 BXGD003593 Retinoschisis Eye Diseases
C0155299 BXGD003783 Coloboma of optic disc Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0162285 BXGD003928 Edema of eyelid Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases; Cardiovascular Diseases
C0162298 BXGD003933 Joint stiffness Musculoskeletal Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0205696 BXGD004107 Anaplastic carcinoma Neoplasms
C0205697 BXGD004108 Carcinoma, Spindle-Cell Neoplasms
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0205699 BXGD004110 Carcinomatosis Neoplasms
C0206686 BXGD004241 Adrenocortical carcinoma Neoplasms; Endocrine System Diseases
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221074 BXGD004388 Depression, Postpartum Female Urogenital Diseases and Pregnancy Complications; Mental Disorders
C0221217 BXGD004408 Neck webbing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0221271 BXGD004431 Elastosis perforans serpiginosa Skin and Connective Tissue Diseases
C0232466 BXGD004543 Feeding difficulties
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0240063 BXGD005015 Coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0240583 BXGD005044 Short upturned nose
C0242723 BXGD005193 Parasitemia Pathological Conditions, Signs and Symptoms; Infections
C0264722 BXGD005419 Chronic congestive heart failure Cardiovascular Diseases
C0265535 BXGD005544 Trigonocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0265541 BXGD005545 Cranioschisis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0266449 BXGD005670 Congenital anomaly of brain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Nervous System Diseases
C0266463 BXGD005675 Lissencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0266464 BXGD005676 Polymicrogyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0266483 BXGD005680 Pachygyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0266544 BXGD005691 Microcornea Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266551 BXGD005693 Congenital coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0268079 BXGD005812 Hyperphosphaturia Nutritional and Metabolic Diseases
C0277528 BXGD006472 Traveler's diarrhea Digestive System Diseases; Infections
C0277828 BXGD006480 Late fontanel closure
C0278488 BXGD006515 Carcinoma breast stage IV
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0282201 BXGD006799 Phosphate Diabetes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0302142 BXGD006831 Deformity Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0333463 BXGD006954 Senile Plaques Pathological Conditions, Signs and Symptoms
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0339573 BXGD007271 Glaucoma, Primary Open Angle Eye Diseases
C0343641 BXGD007636 Human papilloma virus infection Infections
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346402 BXGD007823 Malignant neoplasm of adrenal cortex Neoplasms; Endocrine System Diseases
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0375381 BXGD007977 Urethral intrinsic sphincter deficiency
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376634 BXGD008006 Craniofacial Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0395971 BXGD008175 Dominant sensorineural hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0410528 BXGD008430 Skeletal dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0423110 BXGD008471 Downward slant of palpebral fissure
C0423113 BXGD008473 Telecanthus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0423318 BXGD008478 Heterochromia iridis Pathological Conditions, Signs and Symptoms; Eye Diseases; Skin and Connective Tissue Diseases
C0426415 BXGD008560 Large nose
C0426421 BXGD008561 Wide nose
C0432072 BXGD008718 Dysmorphic features
C0432215 BXGD008739 Progressive pseudorheumatoid dysplasia Musculoskeletal Diseases
C0452138 BXGD008831 Sensorineural hearing loss, bilateral Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0456070 BXGD008863 Growth delay
C0456132 BXGD008869 Large fontanelle
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0497552 BXGD009067 Congenital neurologic anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0521525 BXGD009139 Short neck
C0521620 BXGD009150 Dilatation of ureter Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0557874 BXGD009444 Global developmental delay
C0578038 BXGD009542 Thin lips
C0578870 BXGD009553 Chronic idiopathic urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600260 BXGD009701 Lung Diseases, Obstructive Respiratory Tract Diseases
C0677949 BXGD009740 Stage III Colorectal Cancer Digestive System Diseases; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0729353 BXGD009924 Subfertility Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751406 BXGD010428 Post-Traumatic Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0751713 BXGD010564 Inclusion Body Myopathy, Sporadic Musculoskeletal Diseases; Nervous System Diseases
C0852036 BXGD010934 Pregnancy associated hypertension Female Urogenital Diseases and Pregnancy Complications; Cardiovascular Diseases
C0857379 BXGD011148 Abnormality of the pinna
C0877015 BXGD011327 Pelvic Organ Prolapse Pathological Conditions, Signs and Symptoms
C0877635 BXGD011356 Cytomegalovirus viremia Pathological Conditions, Signs and Symptoms; Infections
C0917801 BXGD011412 Sleeplessness Nervous System Diseases; Mental Disorders
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C0973461 BXGD011595 Dysphasia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1135868 BXGD011700 Gestational Trophoblastic Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1141957 BXGD011726 HIV disease progression
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257925 BXGD011814 Mammary Carcinoma, Animal Neoplasms; Animal Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1270972 BXGD012006 Mild cognitive disorder Mental Disorders
C1303001 BXGD012317 Congenital euryblepharon
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1561826 BXGD013364 Overweight and obesity
C1611743 BXGD013456 Familial (FPAH)
C1619738 BXGD013464 Immune Reconstitution Inflammatory Syndrome Immune System Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1837819 BXGD014277 Cerebrofrontofacial Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1839798 BXGD014410 Long nose
C1840264 BXGD014439 IMMUNE SUPPRESSION
C1843156 BXGD014561 Progressive sensorineural hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1844505 BXGD014633 Pointed chin
C1845847 BXGD014760 Coarse facial features Pathological Conditions, Signs and Symptoms
C1847514 BXGD014868 Postnatal microcephaly
C1849340 BXGD015039 Long palpebral fissure
C1849367 BXGD015046 Nasal bridge wide
C1853623 BXGD015348 Fryns-Aftimos Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1855722 BXGD015535 Iris Coloboma with Ptosis, Hypertelorism, and Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1855728 BXGD015536 Low posterior hairline
C1857479 BXGD015705 Short columella
C1857949 BXGD015758 Prominent metopic ridge
C1858172 BXGD015778 Deafness, Autosomal Dominant 20 Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1859717 BXGD015924 Depressed nasal tip
C1865014 BXGD016282 Long philtrum
C1865017 BXGD016283 Thin upper lip vermilion
C1866231 BXGD016388 Full cheeks
C1868571 BXGD016508 Highly arched eyebrow
C1868684 BXGD016527 EAR, PATELLA, SHORT STATURE SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C1956147 BXGD016622 Microlissencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1970280 BXGD016829 Hearing loss begins with loss of high frequencies
C1970281 BXGD016830 Audiogram shows sloping configuration
C1970282 BXGD016831 Deafness, profound, by 6th decade
C2217035 BXGD016952 Stage IIA Colon Cancer AJCC v7
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2931618 BXGD018040 Gestational trophoblastic disease Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C2945695 BXGD018187 Limb ischemia
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C3146250 BXGD018259 Stage III Colorectal Cancer AJCC v7
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3279369 BXGD018754 Microphthalmia (in some patients)
C3281235 BXGD018894 BARAITSER-WINTER SYNDROME 2
C3494422 BXGD018966 Retrognathia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C3539168 BXGD019085 PEROXISOME BIOGENESIS DISORDER, COMPLEMENTATION GROUP A
C3549665 BXGD019125 Deafness (in some patients)
C3554568 BXGD019222 Young adult onset
C3665464 BXGD019289 Dementia due to Alzheimer's disease (disorder) Nervous System Diseases; Mental Disorders
C3711374 BXGD019382 Nonsyndromic Deafness Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3808883 BXGD019557 Short neck (in some patients)
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4012410 BXGD020121 Enlarged ventricles (in some patients)
C4021370 BXGD020616 Duplication of thumb phalanx
C4022153 BXGD020884 Cerebral cortical hemiatrophy
C4023018 BXGD021068 Subcortical cerebral atrophy
C4025285 BXGD021625 Microspherocytosis
C4025790 BXGD021791 Specific learning disability
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4229649 BXGD022295 Heart defect (in some patients)
C4229650 BXGD022296 Pterygium colli (in some patients)
C4229651 BXGD022297 Hypertelorism/telecanthus
C4229652 BXGD022298 Eye coloboma (in some patients)
C4229653 BXGD022299 Trigonocephaly/metopic ridge
C4231117 BXGD022301 Pectus (in some patients)
C4231118 BXGD022302 Kyphosis/scoliosis (in some patients)
C4231120 BXGD022303 Prominent nasal root on profile
C4231121 BXGD022304 Large, squared nose tip
C4231123 BXGD022305 Retrognathia (in some patients)
C4231124 BXGD022306 Prominent/full/wide cheeks
C4290046 BXGD022507 trachomatis
C4505456 BXGD022964 HIV Coinfection Infections; Immune System Diseases
C4525122 BXGD023119 Stage IIA Colon Cancer AJCC v8
C4551689 BXGD023393 Sleep-Disordered Breathing Respiratory Tract Diseases; Nervous System Diseases
C4554007 BXGD023555 Uveoretinal Coloboma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C4708599 BXGD023729 Coloboma of choroid and retina
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721919 BXGD023785 malignant neoplasm of large intestine stage IIa
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0002616 Copper 63.55
BXGC0051100 dihydroartemisinin 284.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein