Showing entry for Locally advanced breast cancer


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD019016
Disease NameLocally advanced breast cancer
Disease CUI IdC3495949
MeSH Codes   
Disease Class Name
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14786 BXGT004099 Neuropilin-1 8829 reviewed
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O43278 BXGT004581 Kunitz-type protease inhibitor 1 6692 reviewed
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P18433 BXGT008403 Receptor-type tyrosine-protein phosphatase alpha 5786 reviewed Enzyme
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q08881 BXGT013012 Tyrosine-protein kinase ITK/TSK 3702 reviewed Kinase
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15392 BXGT013566 Delta(24)-sterol reductase 1718 reviewed Enzyme
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q99933 BXGT019976 BAG family molecular chaperone regulator 1 573 reviewed
Q9BXH1 BXGT020167 Bcl-2-binding component 3 27113 reviewed
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9Y5W5 BXGT022303 Wnt inhibitory factor 1 11197 reviewed Calcium-binding protein
Q9Y5Y6 BXGT022308 Suppressor of tumorigenicity 14 protein 6768 reviewed Enzyme
Q9GZQ8 BXGT023414 Microtubule-associated proteins 1A/1B light chain 3B 81631 reviewed Cellular structure
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease