Showing entry for Monocarboxylate transporter 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004891
Protein NameMonocarboxylate transporter 2
Uniport IdO60669
GeneSLC16A7
Gene Id9194
DomainMFS_1
Pfam PF07690  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0035873 lactate transmembrane transport
Biological Process GO:0015718 monocarboxylic acid transport
Biological Process GO:1901475 pyruvate transmembrane transport
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0015129 lactate transmembrane transporter activity
molecular function GO:0008028 monocarboxylic acid transmembrane transporter activity
molecular function GO:0005477 pyruvate secondary active transmembrane transporter activity
molecular function GO:0050833 pyruvate transmembrane transporter activity
molecular function GO:0015293 symporter activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-425366 Transport of bile salts and organic acids, metal ions and amine compounds
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-433692 Proton-coupled monocarboxylate transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017638 BXGD001132 Glioma Neoplasms
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028960 BXGD002101 Oligospermia Male Urogenital Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0150055 BXGD003401 Chronic pain Pathological Conditions, Signs and Symptoms
C0154830 BXGD003746 Proliferative diabetic retinopathy Pathological Conditions, Signs and Symptoms; Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0270715 BXGD006089 Degenerative Diseases, Central Nervous System Nervous System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C4049272 BXGD021918 Tumour budding
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000077 p-Coumaric acid ethyl ester 192.21
BXGC0001887 m-Coumaric acid 164.16
BXGC0021732 3-Hydroxybutyric Acid 104.05
BXGC0038275 Pyruvic Acid 88.02
BXGC0041324 Lactic Acid 90.03
BXGC0047529 2-hydroxybutyric acid 104.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein