adisease

Showing entry for Oligospermia

General Disease Information
BXGD Id	BXGD002101
Disease Name	Oligospermia
Disease CUI Id	C0028960
MeSH Codes	C12
Disease Class Name	Male Urogenital Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000119
Human Phenotype Ontology Term	Abnormality of the genitourinary system
Disease Ontology Id	DOID:630 DOID:7
Disease Ontology Class Name	genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O60669	BXGT004891	Monocarboxylate transporter 2	9194	reviewed	Transporter
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01215	BXGT005743	Glycoprotein hormones alpha chain	1081	reviewed
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02743	BXGT005937	Serum amyloid P-component	325	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04181	BXGT006165	Ornithine aminotransferase, mitochondrial	4942	reviewed	Enzyme
P04279	BXGT006183	Semenogelin-1	6406	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08758	BXGT006821	Annexin A5	308	reviewed
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09848	BXGT006929	Lactase-phlorizin hydrolase	3938	reviewed	Enzyme
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10909	BXGT007630	Clusterin	1191	reviewed
P11940	BXGT007762	Polyadenylate-binding protein 1	26986	reviewed
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P18669	BXGT008419	Phosphoglycerate mutase 1	5223	reviewed
P19784	BXGT008513	Casein kinase II subunit alpha'	1459	reviewed	Kinase
P21583	BXGT008667	Kit ligand	4254	reviewed
P23945	BXGT008931	Follicle-stimulating hormone receptor	2492	reviewed	G-protein coupled receptor
P24941	BXGT009002	Cyclin-dependent kinase 2	1017	reviewed	Kinase
P25440	BXGT009044	Bromodomain-containing protein 2	6046	reviewed	Epigenetic regulator
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31213	BXGT009515	3-oxo-5-alpha-steroid 4-dehydrogenase 2	6716	reviewed	Enzyme
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P34913	BXGT009770	Bifunctional epoxide hydrolase 2	2053	reviewed	Enzyme
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P49711	BXGT010728	Transcriptional repressor CTCF	10664	reviewed	Transcription factor
P51843	BXGT010897	Nuclear receptor subfamily 0 group B member 1	190	reviewed	Nuclear receptor
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54278	BXGT011038	Mismatch repair endonuclease PMS2	5395	reviewed	Nucleic acid binding
P60568	BXGT011315	Interleukin-2	3558	reviewed
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P63146	BXGT011504	Ubiquitin-conjugating enzyme E2 B	7320	reviewed
P78396	BXGT011842	Cyclin-A1	8900	reviewed	Enzyme modulator
Q01484	BXGT012592	Ankyrin-2	287	reviewed
Q01831	BXGT012621	DNA repair protein complementing XP-C cells	7508	reviewed	Nucleic acid binding
Q08345	BXGT012982	Epithelial discoidin domain-containing receptor 1	780	reviewed	Kinase
Q13285	BXGT013335	Steroidogenic factor 1	2516	reviewed	Nuclear receptor
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q15349	BXGT013558	Ribosomal protein S6 kinase alpha-2	6196	reviewed	Kinase
Q4U2R8	BXGT014891	Solute carrier family 22 member 6	9356	reviewed	Transporter
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6VVX0	BXGT016585	Vitamin D 25-hydroxylase	120227	reviewed
Q86W24	BXGT017622	NACHT, LRR and PYD domains-containing protein 14	338323	reviewed
Q86X55	BXGT017627	Histone-arginine methyltransferase CARM1	10498	reviewed	Epigenetic regulator
Q8WWY3	BXGT019006	U4/U6 small nuclear ribonucleoprotein Prp31	26121	reviewed	Nucleic acid binding
Q96LA8	BXGT019691	Protein arginine N-methyltransferase 6	55170	reviewed	Epigenetic regulator
Q96T88	BXGT019747	E3 ubiquitin-protein ligase UHRF1	29128	reviewed
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q9H361	BXGT020460	Polyadenylate-binding protein 3	5042	reviewed
Q9H6X2	BXGT020486	Anthrax toxin receptor 1	84168	reviewed	Receptor
Q9NSI6	BXGT021208	Bromodomain and WD repeat-containing protein 1	54014	reviewed
Q9P1W8	BXGT021295	Signal-regulatory protein gamma	55423	reviewed	Signaling
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UHL0	BXGT021702	ATP-dependent RNA helicase DDX25	29118	reviewed
Q9UPY3	BXGT021802	Endoribonuclease Dicer	23405	reviewed	Enzyme
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y6F8	BXGT022329	Testis-specific chromodomain protein Y 1	9085	reviewed
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q8TBZ3	BXGT023141	WD repeat-containing protein 20	91833	reviewed
P56703	BXGT023722	Proto-oncogene Wnt-3	7473	reviewed	Signaling
Q8IYM1	BXGT024860	Septin-12	124404	reviewed	Enzyme modulator
O14649	BXGT025486	Potassium channel subfamily K member 3	3777	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}