Showing entry for Tumor necrosis factor receptor superfamily member 21


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005133
Protein NameTumor necrosis factor receptor superfamily member 21
Uniport IdO75509
GeneTNFRSF21
Gene Id27242
DomainDeath; TNFR_c6
Pfam PF00531   PF00020  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007413 axonal fasciculation
Biological Process GO:0001783 B cell apoptotic process
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0006959 humoral immune response
Biological Process GO:0042552 myelination
Biological Process GO:0030889 negative regulation of B cell proliferation
Biological Process GO:0032693 negative regulation of interleukin-10 production
Biological Process GO:0032696 negative regulation of interleukin-13 production
Biological Process GO:0032714 negative regulation of interleukin-5 production
Biological Process GO:0031642 negative regulation of myelination
Biological Process GO:0042130 negative regulation of T cell proliferation
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:0097252 oligodendrocyte apoptotic process
Biological Process GO:0019216 regulation of lipid metabolic process
Biological Process GO:0048713 regulation of oligodendrocyte differentiation
Biological Process GO:0050852 T cell receptor signaling pathway
cellular component GO:0030424 axon
cellular component GO:0005737 cytoplasm
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0031226 intrinsic component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1989781 PPARA activates gene expression
R-HSA-400206 Regulation of lipid metabolism by PPARalpha
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0017639 BXGD001133 Gliosis Pathological Conditions, Signs and Symptoms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020981 BXGD001474 Angioimmunoblastic Lymphadenopathy Immune System Diseases; Hemic and Lymphatic Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0024894 BXGD001810 Mastitis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0393554 BXGD008087 Amyotrophic Lateral Sclerosis With Dementia Nutritional and Metabolic Diseases; Nervous System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0543859 BXGD009298 Amyotrophic Lateral Sclerosis, Guam Form Nutritional and Metabolic Diseases; Nervous System Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1608408 BXGD013434 Malignant transformation
C3887640 BXGD019908 Astrocytosis Pathological Conditions, Signs and Symptoms
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein