adisease

General Disease Information
BXGD Id	BXGD008087
Disease Name	Amyotrophic Lateral Sclerosis With Dementia
Disease CUI Id	C0393554
MeSH Codes	C18 C10
Disease Class Name	Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O75509	BXGT005133	Tumor necrosis factor receptor superfamily member 21	27242	reviewed
P00390	BXGT005526	Glutathione reductase, mitochondrial	2936	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30531	BXGT009432	Sodium- and chloride-dependent GABA transporter 1	6529	reviewed	Transporter
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P42658	BXGT010327	Dipeptidyl aminopeptidase-like protein 6	1804	reviewed	Enzyme
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P47712	BXGT010577	Cytosolic phospholipase A2	5321	reviewed	Enzyme
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q96NX5	BXGT019702	Calcium/calmodulin-dependent protein kinase type 1G	57172	reviewed	Kinase
Q96PY6	BXGT019712	Serine/threonine-protein kinase Nek1	4750	reviewed	Kinase
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}