Showing entry for Kidney Failure, Acute


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001571
Disease NameKidney Failure, Acute
Disease CUI IdC0022660
MeSH Codes C13   C12  
Disease Class NameFemale Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000119  
Human Phenotype Ontology TermAbnormality of the genitourinary system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00429 BXGT003919 Dynamin-1-like protein 10059 reviewed Enzyme modulator
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14745 BXGT004090 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 9368 reviewed
O14791 BXGT004101 Apolipoprotein L1 8542 reviewed Transporter
O14964 BXGT004116 Hepatocyte growth factor-regulated tyrosine kinase substrate 9146 reviewed
O15119 BXGT004128 T-box transcription factor TBX3 6926 reviewed Transcription factor
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15244 BXGT004140 Solute carrier family 22 member 2 6582 reviewed Transporter
O43278 BXGT004581 Kunitz-type protease inhibitor 1 6692 reviewed
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43683 BXGT004614 Mitotic checkpoint serine/threonine-protein kinase BUB1 699 reviewed Kinase
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60488 BXGT004878 Long-chain-fatty-acid--CoA ligase 4 2182 reviewed Enzyme
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 54600 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75509 BXGT005133 Tumor necrosis factor receptor superfamily member 21 27242 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O94759 BXGT005327 Transient receptor potential cation channel subfamily M member 2 7226 reviewed Ion channel
O95257 BXGT005365 Growth arrest and DNA damage-inducible protein GADD45 gamma 10912 reviewed
O95398 BXGT005378 Rap guanine nucleotide exchange factor 3 10411 reviewed Enzyme modulator
O95631 BXGT005387 Netrin-1 9423 reviewed Enzyme modulator
O95865 BXGT005404 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 23564 reviewed Enzyme
O95931 BXGT005407 Chromobox protein homolog 7 23492 reviewed Epigenetic regulator
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00451 BXGT005545 Coagulation factor VIII 2157 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00751 BXGT005643 Complement factor B 629 reviewed
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00915 BXGT005689 Carbonic anhydrase 1 759 reviewed
P01008 BXGT005713 Antithrombin-III 462 reviewed Enzyme modulator
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01023 BXGT005718 Alpha-2-macroglobulin 2 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02144 BXGT005853 Myoglobin 4151 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02743 BXGT005937 Serum amyloid P-component 325 reviewed
P02750 BXGT005942 Leucine-rich alpha-2-glycoprotein 116844 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02760 BXGT005948 Protein AMBP 259 reviewed
P02763 BXGT005951 Alpha-1-acid glycoprotein 1 5004 reviewed
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P02794 BXGT005967 Ferritin heavy chain 2495 reviewed Storage
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3156 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P05413 BXGT006355 Fatty acid-binding protein, heart 2170 reviewed
P06276 BXGT006430 Cholinesterase 590 reviewed
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P06576 BXGT006454 ATP synthase subunit beta, mitochondrial 506 reviewed Transporter
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07148 BXGT006559 Fatty acid-binding protein, liver 2168 reviewed
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07686 BXGT006657 Beta-hexosaminidase subunit beta 3074 reviewed Enzyme
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08034 BXGT006716 Gap junction beta-1 protein 2705 reviewed Cell-cell junction
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08263 BXGT006759 Glutathione S-transferase A1 2938 reviewed
P08603 BXGT006798 Complement factor H 3075 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08833 BXGT006827 Insulin-like growth factor-binding protein 1 3484 reviewed Enzyme modulator
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09327 BXGT006877 Villin-1 7429 reviewed Cellular structure
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P10909 BXGT007630 Clusterin 1191 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11086 BXGT007652 Phenylethanolamine N-methyltransferase 5409 reviewed Enzyme
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P11142 BXGT007658 Heat shock cognate 71 kDa protein 3312 reviewed
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11474 BXGT007710 Steroid hormone receptor ERR1 2101 reviewed Nuclear receptor
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12081 BXGT007772 Histidine--tRNA ligase, cytoplasmic 3035 reviewed Enzyme
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P13866 BXGT007963 Sodium/glucose cotransporter 1 6523 reviewed Transporter
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14616 BXGT008026 Insulin receptor-related protein 3645 reviewed Kinase
P14679 BXGT008039 Tyrosinase 7299 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15086 BXGT008078 Carboxypeptidase B 1360 reviewed Enzyme
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16109 BXGT008194 P-selectin 6403 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16435 BXGT008226 NADPH--cytochrome P450 reductase 5447 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16581 BXGT008245 E-selectin 6401 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17405 BXGT008304 Sphingomyelin phosphodiesterase 6609 reviewed Enzyme
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18075 BXGT008375 Bone morphogenetic protein 7 655 reviewed Signaling
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P19525 BXGT008492 Interferon-induced, double-stranded RNA-activated protein kinase 5610 reviewed Kinase
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20160 BXGT008548 Azurocidin 566 reviewed Enzyme
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21730 BXGT008687 C5a anaphylatoxin chemotactic receptor 1 728 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P23786 BXGT008906 Carnitine O-palmitoyltransferase 2, mitochondrial 1376 reviewed Enzyme
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P24468 BXGT008969 COUP transcription factor 2 7026 reviewed Nuclear receptor
P24855 BXGT008998 Deoxyribonuclease-1 1773 reviewed
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29375 BXGT009338 Lysine-specific demethylase 5A 5927 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29622 BXGT009370 Kallistatin 5267 reviewed Enzyme modulator
P30041 BXGT009393 Peroxiredoxin-6 9588 reviewed Enzyme
P30046 BXGT009396 D-dopachrome decarboxylase 1652 reviewed Enzyme
P30405 BXGT009423 Peptidyl-prolyl cis-trans isomerase F, mitochondrial 10105 reviewed
P30411 BXGT009424 B2 bradykinin receptor 624 reviewed G-protein coupled receptor
P30519 BXGT009429 Heme oxygenase 2 3163 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31025 BXGT009500 Lipocalin-1 3933 reviewed Enzyme
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31785 BXGT009577 Cytokine receptor common subunit gamma 3561 reviewed Signaling
P31939 BXGT009584 Bifunctional purine biosynthesis protein PURH 471 reviewed Enzyme
P32119 BXGT009600 Peroxiredoxin-2 7001 reviewed Enzyme
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P33681 BXGT009739 T-lymphocyte activation antigen CD80 941 reviewed
P34913 BXGT009770 Bifunctional epoxide hydrolase 2 2053 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35398 BXGT009825 Nuclear receptor ROR-alpha 6095 reviewed Nuclear receptor
P35613 BXGT009856 Basigin 682 reviewed
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36551 BXGT009927 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1371 reviewed Enzyme
P36969 BXGT009949 Phospholipid hydroperoxide glutathione peroxidase 2879 reviewed Enzyme
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P39019 BXGT010082 40S ribosomal protein S19 6223 reviewed Nucleic acid binding
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P43652 BXGT010405 Afamin 173 reviewed Transporter
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46734 BXGT010537 Dual specificity mitogen-activated protein kinase kinase 3 5606 reviewed Kinase
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P46939 BXGT010555 Utrophin 7402 reviewed
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49116 BXGT010678 Nuclear receptor subfamily 2 group C member 2 7182 reviewed Nuclear receptor
P49585 BXGT010712 Choline-phosphate cytidylyltransferase A 5130 reviewed
P49662 BXGT010724 Caspase-4 837 reviewed Enzyme
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50053 BXGT010769 Ketohexokinase 3795 reviewed Kinase
P50579 BXGT010812 Methionine aminopeptidase 2 10988 reviewed
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51575 BXGT010861 P2X purinoceptor 1 5023 reviewed Ion channel
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P52594 BXGT010936 Arf-GAP domain and FG repeat-containing protein 1 3267 reviewed
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P54707 BXGT011068 Potassium-transporting ATPase alpha chain 2 479 reviewed Transporter
P54802 BXGT011081 Alpha-N-acetylglucosaminidase 4669 reviewed
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P55157 BXGT011108 Microsomal triglyceride transfer protein large subunit 4547 reviewed Transporter
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P55263 BXGT011115 Adenosine kinase 132 reviewed Kinase
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR 2671 reviewed Enzyme
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
P57764 BXGT011217 Gasdermin-D 79792 reviewed
P58004 BXGT011222 Sestrin-2 83667 reviewed Enzyme
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60903 BXGT011339 Protein S100-A10 6281 reviewed Calcium-binding protein
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
P62491 BXGT011430 Ras-related protein Rab-11A 8766 reviewed
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P69892 BXGT011647 Hemoglobin subunit gamma-2 3048 reviewed
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P78540 BXGT011848 Arginase-2, mitochondrial 384 reviewed Enzyme
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
P81172 BXGT011935 Hepcidin 57817 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
P98066 BXGT012225 Tumor necrosis factor-inducible gene 6 protein 7130 reviewed
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q00059 BXGT012512 Transcription factor A, mitochondrial 7019 reviewed
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q01118 BXGT012570 Sodium channel protein type 7 subunit alpha 6332 reviewed Ion channel
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q06710 BXGT012887 Paired box protein Pax-8 7849 reviewed
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q08257 BXGT012975 Quinone oxidoreductase 1429 reviewed
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q13126 BXGT013313 S-methyl-5'-thioadenosine phosphorylase 4507 reviewed Enzyme
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q13618 BXGT013382 Cullin-3 8452 reviewed
Q13625 BXGT013384 Apoptosis-stimulating of p53 protein 2 7159 reviewed Enzyme modulator
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14654 BXGT013495 ATP-sensitive inward rectifier potassium channel 11 3767 reviewed Ion channel
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15274 BXGT013556 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 23475 reviewed
Q15722 BXGT013590 Leukotriene B4 receptor 1 1241 reviewed G-protein coupled receptor
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16654 BXGT013650 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 5166 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16739 BXGT013663 Ceramide glucosyltransferase 7357 reviewed Enzyme
Q16820 BXGT013674 Meprin A subunit beta 4225 reviewed Enzyme
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 9356 reviewed Transporter
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q53H47 BXGT015014 Histone-lysine N-methyltransferase SETMAR 6419 reviewed Epigenetic regulator
Q676U5 BXGT016177 Autophagy-related protein 16-1 55054 reviewed
Q6NYC1 BXGT016436 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 23210 reviewed Receptor
Q6ZMJ4 BXGT016628 Interleukin-34 146433 reviewed
Q6ZN16 BXGT016630 Mitogen-activated protein kinase kinase kinase 15 389840 reviewed
Q6ZVN8 BXGT016641 Hemojuvelin 148738 reviewed
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q86TM3 BXGT017607 Probable ATP-dependent RNA helicase DDX53 168400 reviewed
Q86WV6 BXGT017626 Stimulator of interferon genes protein 340061 reviewed
Q8N6T7 BXGT018525 NAD-dependent protein deacetylase sirtuin-6 51548 reviewed Epigenetic regulator
Q8N884 BXGT018528 Cyclic GMP-AMP synthase 115004 reviewed
Q8NB16 BXGT018535 Mixed lineage kinase domain-like protein 197259 reviewed Kinase
Q8NEB9 BXGT018553 Phosphatidylinositol 3-kinase catalytic subunit type 3 5289 reviewed Kinase
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q8TCC7 BXGT018794 Solute carrier family 22 member 8 9376 reviewed Transporter
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8TDS4 BXGT018812 Hydroxycarboxylic acid receptor 2 338442 reviewed
Q8WUM4 BXGT018994 Programmed cell death 6-interacting protein 10015 reviewed Receptor
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96D31 BXGT019635 Calcium release-activated calcium channel protein 1 84876 reviewed Ion channel
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96FL8 BXGT019660 Multidrug and toxin extrusion protein 1 55244 reviewed Transporter
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96S37 BXGT019737 Solute carrier family 22 member 12 116085 reviewed Transporter
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99808 BXGT019964 Equilibrative nucleoside transporter 1 2030 reviewed Transporter
Q99816 BXGT019966 Tumor susceptibility gene 101 protein 7251 reviewed Enzyme
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BXH1 BXGT020167 Bcl-2-binding component 3 27113 reviewed
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9C0B1 BXGT020209 Alpha-ketoglutarate-dependent dioxygenase FTO 79068 reviewed
Q9GZT4 BXGT020424 Serine racemase 63826 reviewed Enzyme
Q9H244 BXGT020448 P2Y purinoceptor 12 64805 reviewed G-protein coupled receptor
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase 9748 reviewed Kinase
Q9H2X6 BXGT020458 Homeodomain-interacting protein kinase 2 28996 reviewed Kinase
Q9H2X9 BXGT020459 Solute carrier family 12 member 5 57468 reviewed Transporter
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 84148 reviewed
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9HCE5 BXGT020531 N6-adenosine-methyltransferase non-catalytic subunit 57721 reviewed Transcription factor
Q9NP79 BXGT021145 Vacuolar protein sorting-associated protein VTA1 homolog 51534 reviewed
Q9NP99 BXGT021148 Triggering receptor expressed on myeloid cells 1 54210 reviewed
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NXA8 BXGT021245 NAD-dependent protein deacylase sirtuin-5, mitochondrial 23408 reviewed Epigenetic regulator
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9UBL9 BXGT021656 P2X purinoceptor 2 22953 reviewed Ion channel
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UER7 BXGT021672 Death domain-associated protein 6 1616 reviewed
Q9UGB7 BXGT021678 Inositol oxygenase 55586 reviewed Enzyme
Q9UIK4 BXGT021720 Death-associated protein kinase 2 23604 reviewed Kinase
Q9ULY5 BXGT021770 C-type lectin domain family 4 member E 26253 reviewed Receptor
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9Y239 BXGT022213 Nucleotide-binding oligomerization domain-containing protein 1 10392 reviewed Enzyme
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y2K2 BXGT022238 Serine/threonine-protein kinase SIK3 23387 reviewed Kinase
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y5S8 BXGT022302 NADPH oxidase 1 27035 reviewed
Q9Y5Y6 BXGT022308 Suppressor of tumorigenicity 14 protein 6768 reviewed Enzyme
Q9Y6K9 BXGT022333 NF-kappa-B essential modulator 8517 reviewed Kinase
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q9UNS1 BXGT022882 Protein timeless homolog 8914 reviewed
P19235 BXGT022895 Erythropoietin receptor 2057 reviewed Receptor
Q9UKG1 BXGT022975 DCC-interacting protein 13-alpha 26060 reviewed
O60502 BXGT023392 Protein O-GlcNAcase 10724 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
Q13007 BXGT023883 Interleukin-24 11009 reviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
O95251 BXGT024818 Histone acetyltransferase KAT7 11143 reviewed Enzyme
O43583 BXGT024866 Density-regulated protein 8562 reviewed Enzyme
Q7L8A9 BXGT025010 Tubulinyl-Tyr carboxypeptidase 1 22846 reviewed
P25090 BXGT025102 N-formyl peptide receptor 2 2358 reviewed G-protein coupled receptor
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
Q96RD7 BXGT025890 Pannexin-1 24145 reviewed Ion channel
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease