Showing entry for Thymidylate synthase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006648
Protein NameThymidylate synthase
Uniport IdP07607
GeneTyms
Gene Id22171
DomainThymidylat_synt
Pfam PF00303  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0051216 cartilage development
Biological Process GO:0007623 circadian rhythm
Biological Process GO:0048589 developmental growth
Biological Process GO:0006231 dTMP biosynthetic process
Biological Process GO:0006235 dTTP biosynthetic process
Biological Process GO:0060574 intestinal epithelial cell maturation
Biological Process GO:0097421 liver regeneration
Biological Process GO:0032259 methylation
Biological Process GO:0019048 modulation by virus of host process
Biological Process GO:0017148 negative regulation of translation
Biological Process GO:0006417 regulation of translation
Biological Process GO:0034097 response to cytokine
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0051593 response to folic acid
Biological Process GO:0051384 response to glucocorticoid
Biological Process GO:0046683 response to organophosphorus
Biological Process GO:0032570 response to progesterone
Biological Process GO:0009636 response to toxic substance
Biological Process GO:0033189 response to vitamin A
Biological Process GO:0035999 tetrahydrofolate interconversion
Biological Process GO:0019860 uracil metabolic process
molecular function GO:0008144 drug binding
molecular function GO:0005542 folic acid binding
molecular function GO:0003729 mRNA binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:1990825 sequence-specific mRNA binding
molecular function GO:0004799 thymidylate synthase activity
molecular function GO:0000900 translation repressor activity, mRNA regulatory element binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005743 mitochondrial inner membrane
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
cellular component GO:0005730 nucleolus
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000759 Arabinan 243.22
BXGC0007530 Folic acid 441.4
BXGC0019003 Levomefolic Acid 459.19
BXGC0049801 Thymidine 242.09
BXGC0050471 Fluorouracil 130.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein