Showing entry for Ras-related protein Rap-2a


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007539
Protein NameRas-related protein Rap-2a
Uniport IdP10114
GeneRAP2A
Gene Id5911
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031532 actin cytoskeleton reorganization
Biological Process GO:0034613 cellular protein localization
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:0030033 microvillus assembly
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0031954 positive regulation of protein autophosphorylation
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0032486 Rap protein signal transduction
Biological Process GO:0048814 regulation of dendrite morphogenesis
Biological Process GO:0046328 regulation of JNK cascade
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0000287 magnesium ion binding
cellular component GO:0005829 cytosol
cellular component GO:0030496 midbody
cellular component GO:0005886 plasma membrane
cellular component GO:0055037 recycling endosome
cellular component GO:0055038 recycling endosome membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0242723 BXGD005193 Parasitemia Pathological Conditions, Signs and Symptoms; Infections
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1864040 BXGD016210 Cerebral Cavernous Malformations 3 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein