Showing entry for CTP synthase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008345
Protein NameCTP synthase 1
Uniport IdP17812
GeneCTPS1
Gene Id1503
DomainCTP_synth_N; GATase
Pfam PF06418   PF00117  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00240 Pyrimidine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0044210 'de novo' CTP biosynthetic process
Biological Process GO:0042100 B cell proliferation
Biological Process GO:0006241 CTP biosynthetic process
Biological Process GO:0006541 glutamine metabolic process
Biological Process GO:0006139 nucleobase-containing compound metabolic process
Biological Process GO:0015949 nucleobase-containing small molecule interconversion
Biological Process GO:0019856 pyrimidine nucleobase biosynthetic process
Biological Process GO:0042493 response to drug
Biological Process GO:0042098 T cell proliferation
molecular function GO:0005524 ATP binding
molecular function GO:0003883 CTP synthase activity
molecular function GO:0042802 identical protein binding
cellular component GO:0097268 cytoophidium
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-499943 Interconversion of nucleotide di- and triphosphates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0005890 BXGD000345 Body Height
C0005938 BXGD000351 Bone Density
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024312 BXGD001766 Lymphopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1837066 BXGD014190 Recurrent viral infection Infections
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711630 BXGD017484 Combined immunodeficiency disease
C4014617 BXGD020155 IMMUNODEFICIENCY 24
C4706524 BXGD023698 Severe combined immunodeficiency due to CTPS1 deficiency
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012340 L-glutamine 146.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein