Showing entry for B-CELL MALIGNANCY, LOW-GRADE


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD016526
Disease NameB-CELL MALIGNANCY, LOW-GRADE
Disease CUI IdC1868683
MeSH Codes   
Disease Class Name
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00429 BXGT003919 Dynamin-1-like protein 10059 reviewed Enzyme modulator
O14727 BXGT004084 Apoptotic protease-activating factor 1 317 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15244 BXGT004140 Solute carrier family 22 member 2 6582 reviewed Transporter
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O43246 BXGT004577 Cationic amino acid transporter 4 6545 reviewed Transporter
O43521 BXGT004598 Bcl-2-like protein 11 10018 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O95256 BXGT005364 Interleukin-18 receptor accessory protein 8807 reviewed Receptor
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00740 BXGT005634 Coagulation factor IX 2158 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01732 BXGT005782 T-cell surface glycoprotein CD8 alpha chain 925 reviewed
P03950 BXGT006116 Angiogenin 283 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06729 BXGT006486 T-cell surface antigen CD2 914 reviewed
P06734 BXGT006491 Low affinity immunoglobulin epsilon Fc receptor 2208 reviewed Receptor
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08236 BXGT006752 Beta-glucuronidase 2990 reviewed
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08603 BXGT006798 Complement factor H 3075 reviewed
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08700 BXGT006816 Interleukin-3 3562 reviewed
P08758 BXGT006821 Annexin A5 308 reviewed
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09172 BXGT006865 Dopamine beta-hydroxylase 1621 reviewed
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P11912 BXGT007758 B-cell antigen receptor complex-associated protein alpha chain 973 reviewed Receptor
P14151 BXGT007990 L-selectin 6402 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15309 BXGT008105 Prostatic acid phosphatase 55 reviewed Enzyme
P15498 BXGT008133 Proto-oncogene vav 7409 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15813 BXGT008158 Antigen-presenting glycoprotein CD1d 912 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17812 BXGT008345 CTP synthase 1 1503 reviewed Enzyme
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P19525 BXGT008492 Interferon-induced, double-stranded RNA-activated protein kinase 5610 reviewed Kinase
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20701 BXGT008591 Integrin alpha-L 3683 reviewed
P20702 BXGT008592 Integrin alpha-X 3687 reviewed
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P22749 BXGT008803 Granulysin 10578 reviewed
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27707 BXGT009201 Deoxycytidine kinase 1633 reviewed Kinase
P27815 BXGT009208 cAMP-specific 3',5'-cyclic phosphodiesterase 4A 5141 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29017 BXGT009305 T-cell surface glycoprotein CD1c 911 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32302 BXGT009619 C-X-C chemokine receptor type 5 643 reviewed G-protein coupled receptor
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P33681 BXGT009739 T-lymphocyte activation antigen CD80 941 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43403 BXGT010385 Tyrosine-protein kinase ZAP-70 7535 reviewed Kinase
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49411 BXGT010703 Elongation factor Tu, mitochondrial 7284 reviewed Enzyme
P49888 BXGT010756 Estrogen sulfotransferase 6783 reviewed
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P54136 BXGT011033 Arginine--tRNA ligase, cytoplasmic 5917 reviewed
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00653 BXGT012541 Nuclear factor NF-kappa-B p100 subunit 4791 reviewed Transcription factor
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16548 BXGT013636 Bcl-2-related protein A1 597 reviewed Signaling
Q16827 BXGT013675 Receptor-type tyrosine-protein phosphatase O 5800 reviewed
Q6GTX8 BXGT016315 Leukocyte-associated immunoglobulin-like receptor 1 3903 reviewed Receptor
Q8WXI8 BXGT019014 C-type lectin domain family 4 member D 338339 reviewed
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q96D31 BXGT019635 Calcium release-activated calcium channel protein 1 84876 reviewed Ion channel
Q96RJ3 BXGT019729 Tumor necrosis factor receptor superfamily member 13C 115650 reviewed
Q96T68 BXGT019746 Histone-lysine N-methyltransferase SETDB2 83852 reviewed
Q99467 BXGT019923 CD180 antigen 4064 reviewed Receptor
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99704 BXGT019950 Docking protein 1 1796 reviewed
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q99933 BXGT019976 BAG family molecular chaperone regulator 1 573 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NR12 BXGT021174 PDZ and LIM domain protein 7 9260 reviewed Cellular structure
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NUX5 BXGT021220 Protection of telomeres protein 1 25913 reviewed Nucleic acid binding
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NYY3 BXGT021264 Serine/threonine-protein kinase PLK2 10769 reviewed Kinase
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 11040 reviewed Kinase
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
Q9Y3B4 BXGT022255 Splicing factor 3B subunit 6 51639 reviewed
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
P20809 BXGT025043 Interleukin-11 3589 reviewed
P31358 BXGT025061 CAMPATH-1 antigen 1043 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
Q9UIJ7 BXGT026029 GTP:AMP phosphotransferase AK3, mitochondrial 50808 reviewed Kinase
P07315 BXGT026109 Gamma-crystallin C 1420 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease