Showing entry for Alpha-1A adrenergic receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008382
Protein NameAlpha-1A adrenergic receptor
Uniport IdP18130
GeneADRA1A
Gene Id282134
Domain7tm_1
Pfam PF00001  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0045907 positive regulation of vasoconstriction
Biological Process GO:0055117 regulation of cardiac muscle contraction
molecular function GO:0004937 alpha1-adrenergic receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0046982 protein heterodimerization activity
cellular component GO:0005901 caveola
cellular component GO:0005737 cytoplasm
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0031965 nuclear membrane
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0017443 Phenylephrine 167.09
BXGC0021893 Norepinephrine 169.07
BXGC0027118 Tamsulosin 408.17
BXGC0046755 Yohimbine 354.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein