Showing entry for Cyclin-dependent kinase 11B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008623
Protein NameCyclin-dependent kinase 11B
Uniport IdP21127
GeneCDK11B
Gene Id984
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0001558 regulation of cell growth
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0007346 regulation of mitotic cell cycle
Biological Process GO:0050684 regulation of mRNA processing
Biological Process GO:0006355 regulation of transcription, DNA-templated
molecular function GO:0005524 ATP binding
molecular function GO:0004693 cyclin-dependent protein serine/threonine kinase activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0003723 RNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
R-HSA-380287 Centrosome maturation
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019269 BXGD001310 Hermaphroditism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0022548 BXGD001551 Keloid Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0023827 BXGD001707 liposarcoma Neoplasms
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0278608 BXGD006549 Adult Liposarcoma Neoplasms
C0279984 BXGD006703 Childhood Liposarcoma Neoplasms
C0346429 BXGD007828 Multiple malignancy Neoplasms
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0040305 Indirubin 262.07
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein