Showing entry for Beta-3 adrenergic receptor



                       
General Target Information
BXGT IdBXGT009093
Protein NameBeta-3 adrenergic receptor
Uniport IdP26255
GeneAdrb3
Gene Id25645
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007190 activation of adenylate cyclase activity
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0007568 aging
Biological Process GO:0050873 brown fat cell differentiation
Biological Process GO:0002024 diet induced thermogenesis
Biological Process GO:0042755 eating behavior
Biological Process GO:0031649 heat generation
Biological Process GO:0040015 negative regulation of multicellular organism growth
Biological Process GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0046677 response to antibiotic
Biological Process GO:0009409 response to cold
molecular function GO:0015052 beta3-adrenergic receptor activity
molecular function GO:0031699 beta-3 adrenergic receptor binding
molecular function GO:0004939 beta-adrenergic receptor activity
molecular function GO:0051379 epinephrine binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0051380 norepinephrine binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0007467 alpha-Terpineol 154.25
BXGC0018063 Alprenolol 249.17
BXGC0021893 Norepinephrine 169.07
BXGC0031384 Epinephrine 183.09
BXGC0041240 Atenolol 266.16
BXGC0042222 Propranolol 259.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein