Showing entry for Retinoic acid receptor RXR-alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009286
Protein NameRetinoic acid receptor RXR-alpha
Uniport IdP28700
GeneRxra
Gene Id20181
DomainHormone_recep; Nuc_recep-AF1; zf-C4
Pfam PF00104   PF11825   PF00105  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048856 anatomical structure development
Biological Process GO:0060978 angiogenesis involved in coronary vascular morphogenesis
Biological Process GO:0043010 camera-type eye development
Biological Process GO:0055007 cardiac muscle cell differentiation
Biological Process GO:0060038 cardiac muscle cell proliferation
Biological Process GO:0030154 cell differentiation
Biological Process GO:0007566 embryo implantation
Biological Process GO:0007507 heart development
Biological Process GO:0003007 heart morphogenesis
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0001893 maternal placenta development
Biological Process GO:0060485 mesenchyme development
Biological Process GO:0019048 modulation by virus of host process
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0035357 peroxisome proliferator activated receptor signaling pathway
Biological Process GO:0001890 placenta development
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
Biological Process GO:0045994 positive regulation of translational initiation by iron
Biological Process GO:0060687 regulation of branching involved in prostate gland morphogenesis
Biological Process GO:0031641 regulation of myelination
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0051384 response to glucocorticoid
Biological Process GO:0032526 response to retinoic acid
Biological Process GO:0048384 retinoic acid receptor signaling pathway
Biological Process GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
Biological Process GO:0055012 ventricular cardiac muscle cell differentiation
Biological Process GO:0055010 ventricular cardiac muscle tissue morphogenesis
Biological Process GO:0061032 visceral serous pericardium development
molecular function GO:0031490 chromatin DNA binding
molecular function GO:0003677 DNA binding
molecular function GO:0050692 DNA binding domain binding
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0003690 double-stranded DNA binding
molecular function GO:0019899 enzyme binding
molecular function GO:0042802 identical protein binding
molecular function GO:0050693 LBD domain binding
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0016922 nuclear receptor binding
molecular function GO:0042277 peptide binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0001972 retinoic acid binding
molecular function GO:0042974 retinoic acid receptor binding
molecular function GO:0044323 retinoic acid-responsive element binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0003707 steroid hormone receptor activity
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
molecular function GO:0042809 vitamin D receptor binding
molecular function GO:0070644 vitamin D response element binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0030424 axon
cellular component GO:0005739 mitochondrion
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
cellular component GO:0043235 receptor complex
cellular component GO:0090575 RNA polymerase II transcription regulator complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001030 Artemetin 388.37
BXGC0001875 Chalepin acetate 356.41
BXGC0009649 Dihydrocapsaicin 307.43
BXGC0021836 Honokiol 266.13
BXGC0034894 Oleic Acid 282.26
BXGC0044468 Ergosterol Peroxide 428.33
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein