Showing entry for Disks large homolog 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009499
Protein NameDisks large homolog 4
Uniport IdP31016
GeneDlg4
Gene Id29495
DomainGuanylate_kin; MAGUK_N_PEST; PDZ; PDZ_assoc; SH3_1
Pfam PF00625   PF10608   PF00595   PF10600   PF00018  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097113 AMPA glutamate receptor clustering
Biological Process GO:0098609 cell-cell adhesion
Biological Process GO:0035865 cellular response to potassium ion
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0060997 dendritic spine morphogenesis
Biological Process GO:0097061 dendritic spine organization
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:0035641 locomotory exploration behavior
Biological Process GO:0002091 negative regulation of receptor internalization
Biological Process GO:0050885 neuromuscular process controlling balance
Biological Process GO:0045161 neuronal ion channel clustering
Biological Process GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane
Biological Process GO:1904719 positive regulation of AMPA glutamate receptor clustering
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:0150012 positive regulation of neuron projection arborization
Biological Process GO:0061098 positive regulation of protein tyrosine kinase activity
Biological Process GO:0050806 positive regulation of synaptic transmission
Biological Process GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0035418 protein localization to synapse
Biological Process GO:0043113 receptor clustering
Biological Process GO:0097120 receptor localization to synapse
Biological Process GO:2000821 regulation of grooming behavior
Biological Process GO:0048169 regulation of long-term neuronal synaptic plasticity
Biological Process GO:0048168 regulation of neuronal synaptic plasticity
Biological Process GO:2000310 regulation of NMDA receptor activity
Biological Process GO:0035176 social behavior
Biological Process GO:0016188 synaptic vesicle maturation
Biological Process GO:0071625 vocalization behavior
molecular function GO:0033130 acetylcholine receptor binding
molecular function GO:0031697 beta-1 adrenergic receptor binding
molecular function GO:0031698 beta-2 adrenergic receptor binding
molecular function GO:0031748 D1 dopamine receptor binding
molecular function GO:0005109 frizzled binding
molecular function GO:0035254 glutamate receptor binding
molecular function GO:0019865 immunoglobulin binding
molecular function GO:0035255 ionotropic glutamate receptor binding
molecular function GO:0019900 kinase binding
molecular function GO:0019894 kinesin binding
molecular function GO:0097109 neuroligin family protein binding
molecular function GO:0031812 P2Y1 nucleotide receptor binding
molecular function GO:0030165 PDZ domain binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0019903 protein phosphatase binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0005102 signaling receptor binding
molecular function GO:0098919 structural constituent of postsynaptic density
cellular component GO:0032281 AMPA glutamate receptor complex
cellular component GO:0099031 anchored component of postsynaptic density membrane
cellular component GO:0005911 cell-cell junction
cellular component GO:0030054 cell junction
cellular component GO:0071944 cell periphery
cellular component GO:0044300 cerebellar mossy fiber
cellular component GO:0030863 cortical cytoskeleton
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0032839 dendrite cytoplasm
cellular component GO:0043197 dendritic spine
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0060076 excitatory synapse
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0044224 juxtaparanode region of axon
cellular component GO:0016020 membrane
cellular component GO:0031594 neuromuscular junction
cellular component GO:0043005 neuron projection
cellular component GO:0044306 neuron projection terminus
cellular component GO:0044309 neuron spine
cellular component GO:0005886 plasma membrane
cellular component GO:0098794 postsynapse
cellular component GO:0014069 postsynaptic density
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0045202 synapse
cellular component GO:0097060 synaptic membrane
cellular component GO:0008021 synaptic vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003342 Guanidine 59.07
BXGC0014116 Lysine 147.11
BXGC0027925 Cpg 363.06
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein