Showing entry for Lysine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0014116
Compound NameLysine
Structure
FormulaC6H14N2O2
InchiKeyKDXKERNSBIXSRK-YFKPBYRVSA-O
SMILES[NH3+]CCCC[C@@H](C(=O)O)N
InchiInChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+1/t5-/m0/s1
IUPAC[(1S)-5-amino-1-carboxypentyl]azanium
Molecular Weight147.11
Pubchem Id641599
Chembl Id
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB LYS
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P0A8N3 BXGT007149 Lysine--tRNA ligase reviewed lysS - - - - -
P0A8N5 BXGT007150 Lysine--tRNA ligase, heat inducible reviewed lysU - - - - -
P00800 BXGT005661 Thermolysin reviewed npr - - - - -
P9WIU7 BXGT012332 Diaminopimelate decarboxylase reviewed lysA - - - - -
P00861 BXGT005676 Diaminopimelate decarboxylase reviewed lysA - - - - -
P02911 BXGT005987 Lysine/arginine/ornithine-binding periplasmic protein reviewed argT - - - - -
Q43088 BXGT014584 Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic reviewed RBCMT - - - - -
P35049 BXGT009787 Trypsin reviewed - - - - -
Q58497 BXGT015191 Diaminopimelate decarboxylase reviewed lysA - - - - -
Q8W5Y8 BXGT018965 Ply protein unreviewed ply - - - - -
P24171 BXGT008952 Dipeptidyl carboxypeptidase reviewed dcp - - - - -
P0A6L2 BXGT007063 4-hydroxy-tetrahydrodipicolinate synthase reviewed dapA - - ~500000 - -
Q9XBQ8 BXGT022168 L-lysine 2,3-aminomutase reviewed kamA - - - - -
P9WGR1 BXGT012278 Enoyl-[acyl-carrier-protein] reductase [NADH] reviewed inhA - - - - -
Q9LYU8 BXGT021096 Aspartokinase 1, chloroplastic reviewed AK1 - - - - -
P9WQ77 BXGT012492 Probable L-lysine-epsilon aminotransferase reviewed lat - - - - -
O67728 BXGT005005 tRNA(Ile)-lysidine synthase reviewed tilS - - - - -
Q5SI78 BXGT015706 Arginase unreviewed TTHA1496 - - - - -
P08660 BXGT006806 Lysine-sensitive aspartokinase 3 reviewed lysC - - - - -
P15057 BXGT008076 Lysozyme reviewed CPL1 - - - - -
D0VWX8 BXGT002748 ArtJ unreviewed - - - 490 -
B4XMC6 BXGT002150 Diaminopimelate decarboxylase reviewed lysA - - - - -
P06202 BXGT006421 Periplasmic oligopeptide-binding protein reviewed oppA - - - - -
P96896 BXGT012192 Leucine-responsive regulatory protein unreviewed lrp - - - - -
O59188 BXGT004838 Uncharacterized HTH-type transcriptional regulator PH1519 reviewed fl11 - - - - -
O87198 BXGT005257 Homocitrate synthase reviewed lys20 - - - - -
P26512 BXGT009117 Aspartokinase reviewed lysC - - - - -
P04825 BXGT006271 Aminopeptidase N reviewed pepN - - - - -
Q15046 BXGT013527 Lysine--tRNA ligase reviewed KARS1 Enzyme - - - -
Q9WXM1 BXGT021955 L-Ala-D/L-Glu epimerase reviewed TM_0006 - - - - -
Q5LTV6 BXGT015559 His/Glu/Gln/Arg/opine family ABC transporter, periplasmic His/Glu/Gln/Arg/opine family-binding protein unreviewed SPO1306 - - - - -
Q7MAG0 BXGT017027 BINDING COMPONENT OF ABC TRANSPORTER unreviewed WS0279 - - - - -
Q74NK7 BXGT016833 Uncharacterized protein unreviewed BCE_A0238 - - - - -
P74569 BXGT011738 Aspartate kinase unreviewed lysC - - - - -
P05089 BXGT006310 Arginase-1 reviewed ARG1 Enzyme - - 13100 -
Q9Y823 BXGT022352 Homocitrate synthase, mitochondrial reviewed lys4 - 3560 - - -
D0CFC3 BXGT002673 4-hydroxy-tetrahydrodipicolinate synthase unreviewed dapA - - - - -
Q9I4W3 BXGT020740 4-hydroxy-tetrahydrodipicolinate synthase reviewed dapA - - - - -
Q6P179 BXGT016440 Endoplasmic reticulum aminopeptidase 2 reviewed ERAP2 Enzyme - - - -
Q97MC0 BXGT019813 Aspartokinase unreviewed CA_C0278 - - - - -
Q72JG5 BXGT016745 Amino acid ABC transporter, binding protein unreviewed TT_C0807 - - - - -
F2JXJ3 BXGT003238 L-lysine 6-oxidase reviewed lodA - - - - -
E9QYP0 BXGT003194 L-ornithine N(5)-monooxygenase reviewed sidA - - - - -
Q8PWY1 BXGT018664 Pyrrolysine--tRNA ligase reviewed pylS - - - - -
Q81VW8 BXGT017373 Dihydropteroate synthase unreviewed folP - - - - -
Q9FVC8 BXGT020392 4-hydroxy-tetrahydrodipicolinate synthase 2, chloroplastic reviewed DHDPS2 - - - - -
Q2SXD6 BXGT014187 Lysine--tRNA ligase reviewed lysS - - - - -
Q46E79 BXGT014674 Uncharacterized protein unreviewed Mbar_A0837 - - - - -
P29148 BXGT009316 Bacillolysin reviewed npr - - - - -
D7U7T8 BXGT003012 Uncharacterized protein unreviewed VIT_15s0048g00750 - - - 2000 -
F0L8Z6 BXGT003196 4-hydroxy-tetrahydrodipicolinate synthase unreviewed dapA - - - - -
Q9PPB4 BXGT021346 4-hydroxy-tetrahydrodipicolinate synthase reviewed dapA - - - - -
P53634 BXGT011007 Dipeptidyl peptidase 1 reviewed CTSC Enzyme - - - -
Q8DQQ1 BXGT018019 Uncharacterized protein unreviewed spr0554 - - - - -
Q14498 BXGT013475 RNA-binding protein 39 reviewed RBM39 - - - - -
A9DKW4 BXGT001783 4-hydroxy-tetrahydrodipicolinate synthase unreviewed dapA - - - - -
Q8IDJ8 BXGT018251 Lysine--tRNA ligase unreviewed PF3D7_1350100 - - - - -
A0A0M3KKV6 BXGT000544 Homoserine dehydrogenase unreviewed U5K_01898 - - - - -
Q9UIQ6 BXGT021721 Leucyl-cystinyl aminopeptidase reviewed LNPEP Enzyme - - - -
Q6WVP6 BXGT016599 Arginase unreviewed Smp_059980 - - - - -
P12821 BXGT007849 Angiotensin-converting enzyme reviewed ACE Enzyme - - - -
O42629 BXGT004561 Fructosyl amine:oxygen oxidoreductase unreviewed - - - - -
P53608 BXGT011000 Arginase reviewed rocF - - - - -
P31016 BXGT009499 Disks large homolog 4 reviewed Dlg4 - - - - -
Q5CR27 BXGT015304 Lysine--tRNA ligase unreviewed cgd4_2370 - - - - -
D9UBW0 BXGT003041 Lysine cyclodeaminase unreviewed pipA - - - - -
B7M7I1 BXGT002258 4-hydroxy-tetrahydrodipicolinate synthase reviewed dapA - - - - -
M1V4H9 BXGT003851 Dihydrodipicolinate synthase unreviewed CYME_CME179C - - - - -
A0PV47 BXGT000857 Lysine--tRNA ligase unreviewed lysS - - - - -
P9WFW3 BXGT012251 Aspartate--tRNA(Asp/Asn) ligase reviewed aspS - - - - -
P09890 BXGT006939 Diaminopimelate decarboxylase reviewed lysA - - - - -
Q8VUS5 BXGT018951 [LysW]-lysine hydrolase reviewed lysK - - - - -
W6JQJ6 BXGT022627 L-amino acid oxidase/monooxygenase unreviewed laao - - - - -
O69077 BXGT005041 Aspartokinase reviewed lysC - - - - -
Q6F3I7 BXGT016272 Dipeptidyl aminopeptidase 4 reviewed dap4 - - - - -
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial reviewed SIRT3 Epigenetic regulator - - - -
W7JP72 BXGT022629 Lysine--tRNA ligase unreviewed PFNF54_04763 - - - - -
G7CF12 BXGT003536 Lysine--tRNA ligase unreviewed lysS - - - - -
H1XW48 BXGT003582 MutT/NUDIX family protein unreviewed Cabys_2252 - - - - -
J3BZS6 BXGT003731 L-lysine 4-hydroxylase reviewed PMI10_03368 - - - - -
P00736 BXGT005632 Complement C1r subcomponent reviewed C1R Enzyme - - - -
C7QJ42 BXGT002605 L-lysine 3-hydroxylase reviewed Caci_0231 - - - - -
P43133 BXGT010359 Thermolysin reviewed nprS - - - - -
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed KMT2A - - - - -
Q949X7 BXGT024898 Diaminopimelate decarboxylase 1, chloroplastic reviewed LYSA1 - - - - -
Q94A94 BXGT024899 Diaminopimelate decarboxylase 2, chloroplastic reviewed LYSA2 - - - - -
G8XHD5 BXGT024960 L-lysine 4-chlorinase reviewed besD - - - - -
B0BAN6 BXGT024995 Lysine--tRNA ligase reviewed lysS - - - - -
B2FQ84 BXGT025889 Lysine--tRNA ligase unreviewed lysS - - - - -
A0A0J9X1X3 BXGT026057 L-lysine oxidase unreviewed - - - - -
Binding DB 50352165
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT005526 Glutathione reductase, mitochondrial reviewed Enzyme GSR - 61200 - -
reviewed BXGT005526 Glutathione reductase, mitochondrial reviewed Enzyme GSR 54600 - - -
CHEMBL n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00008 Garlic Allium sativum Herbs and Spices
BXGF00027 Chinese mustard Brassica juncea Vegetables
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00380 White mustard Sinapis alba Herbs and Spices
BXGF02214 Morus bombycis Morus bombycis Medicinal Plant
BXGF04607 Morus alba Morus alba Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease