acompound

Showing entry for Guanidine

General Compound Information
BXGC Id	BXGC0003342
Compound Name	Guanidine
Structure
Formula	CH5N3
InchiKey	ZRALSGWEFCBTJO-UHFFFAOYSA-N
SMILES	NC(N)=N
Inchi	InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)
IUPAC	guanidine
Molecular Weight	59.07
Pubchem Id	3520
Chembl Id	CHEMBL821

Targets of Information Source

DrugBank

DB00536

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q14353	BXGT013463	Guanidinoacetate N-methyltransferase	reviewed	-	GAMT	approved	-
P07998	BXGT006711	Ribonuclease pancreatic	reviewed	-	RNASE1	approved	-
P78352	BXGT011836	Disks large homolog 4	reviewed	Receptor	DLG4	approved	-
P00720	BXGT005625	Endolysin	reviewed	-	E	approved	-
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	reviewed	Enzyme	ALDH2	approved	inhibitor
P53608	BXGT011000	Arginase	reviewed	-	rocF	approved	-

PDB

GAI

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P31016	BXGT009499	Disks large homolog 4	reviewed	Dlg4	-	-	-	-	-
P0A6E4	BXGT007049	Argininosuccinate synthase	reviewed	argG	-	-	-	-	-
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	reviewed	ALDH2	Enzyme	-	-	-	-
P0C1S6	BXGT007403	Staphopain B	reviewed	sspB	-	-	-	-	-
P61823	BXGT011385	Ribonuclease pancreatic	reviewed	RNASE1	-	-	-	-	-
P00720	BXGT005625	Endolysin	reviewed	E	-	-	-	-	-
O58720	BXGT004809	Divalent-cation tolerance protein CutA	reviewed	cutA	-	-	-	-	-
P10868	BXGT007626	Guanidinoacetate N-methyltransferase	reviewed	Gamt	-	-	-	-	-
P53608	BXGT011000	Arginase	reviewed	rocF	-	-	-	-	-
O57962	BXGT004772	Uncharacterized protein	unreviewed	PH0223	-	-	-	-	-
P23685	BXGT008895	Sodium/calcium exchanger 1	reviewed	SLC8A1	-	-	-	-	-
Q5SI78	BXGT015706	Arginase	unreviewed	TTHA1496	-	-	-	-	-
P04292	BXGT006184	DNA polymerase catalytic subunit	reviewed	UL30	-	-	-	-	-
A1XQQ8	BXGT001063	Structural polyprotein	unreviewed		-	-	-	-	-
P9WPY9	BXGT012480	Arginine repressor	reviewed	argR	-	-	-	-	-
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	reviewed	MDM2	Nucleic acid binding	-	-	-	-
O15151	BXGT004132	Protein Mdm4	reviewed	MDM4	Nucleic acid binding	-	-	-	-
Q9SPD4	BXGT021597	25 kDa protein elicitor	unreviewed	SD21-1	-	-	-	-	-
Q8DVY1	BXGT018054	Putative carbonic anhydrase	unreviewed	SMU_328	-	-	-	-	-
Q977W1	BXGT019783	Topoisomerase V	unreviewed	top5	-	-	-	-	-
P00722	BXGT005626	Beta-galactosidase	reviewed	lacZ	-	-	-	-	-
A3SMJ4	BXGT001193	Mandelate racemase/muconate lactonizing enzyme family protein	unreviewed	ISM_12500	-	-	-	-	-
P47205	BXGT010569	UDP-3-O-acyl-N-acetylglucosamine deacetylase	reviewed	lpxC	-	-	-	-	-
Q837U7	BXGT017476	Putrescine carbamoyltransferase	reviewed	ptcA	-	-	-	-	-
Q9BU89	BXGT020132	Deoxyhypusine hydroxylase	reviewed	DOHH	-	-	-	-	-
P31522	BXGT009548	pH 6 antigen	reviewed	psaA	-	-	-	-	-
Q8NBZ7	BXGT018544	UDP-glucuronic acid decarboxylase 1	reviewed	UXS1	Enzyme	-	-	-	-
Q9RA63	BXGT021437	Chaperone protein ClpB	reviewed	clpB	-	-	-	-	-
Q51817	BXGT014968	Lys-gingipain W83	reviewed	kgp	-	-	-	-	-
P46934	BXGT010553	E3 ubiquitin-protein ligase NEDD4	reviewed	NEDD4	Enzyme	-	-	-	-
Q8WQX9	BXGT018974	Phosphodiesterase	unreviewed	PDEB1	-	-	-	-	-
Q9UPT6	BXGT021801	C-Jun-amino-terminal kinase-interacting protein 3	reviewed	MAPK8IP3	Enzyme modulator	-	-	-	-
D3RVD4	BXGT002898	Thiosulfate dehydrogenase	reviewed	tsdA	-	-	-	-	-
P00698	BXGT005617	Lysozyme C	reviewed	LYZ	-	-	-	-	-
O66512	BXGT004946	RNA-binding protein Hfq	reviewed	hfq	-	-	-	-	-
A8EVM5	BXGT001681	Ion transport protein	unreviewed	Abu_1752	-	-	-	-	-
K5BJ73	BXGT025171	SnoaL-like domain protein	unreviewed	ksi	-	-	-	-	-
Q9WZ62	BXGT022018	Amino acid ABC transporter, periplasmic amino acid-binding protein	unreviewed	TM_0593	-	-	-	-	-

Binding DB

50420178

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT021408	Solute carrier family 22 member 2	reviewed		Slc22a2	713600	-	-	-
reviewed	BXGT016060	Solute carrier family 22 member 1	reviewed		Slc22a1	724200	-	-	-
reviewed	BXGT021408	Solute carrier family 22 member 2	reviewed		Slc22a2	280000	-	-	-
reviewed	BXGT016060	Solute carrier family 22 member 1	reviewed		Slc22a1	-	4470000	-	-
reviewed	BXGT021408	Solute carrier family 22 member 2	reviewed		Slc22a2	-	171000	-	-

CHEMBL

CHEMBL821

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q9R0W2	BXGT021408	Solute carrier family 22 member 2	reviewed	-	Slc22a2	IC50	'='	171000	nM
O75751	BXGT005150	Solute carrier family 22 member 3	reviewed	Transporter	SLC22A3	Ki	'='	6201000	nM
Q63089	BXGT016060	Solute carrier family 22 member 1	reviewed	-	Slc22a1	IC50	'='	4470000	nM
Q63089	BXGT016060	Solute carrier family 22 member 1	reviewed	-	Slc22a1	Ki	'='	724200	nM
O76082	BXGT005175	Solute carrier family 22 member 5	reviewed	Transporter	SLC22A5	Activity	-	-	-
O88446	BXGT005272	Solute carrier family 22 member 3	reviewed	-	Slc22a3	Activity	-	-	-
Q9WTW5	BXGT021935	Solute carrier family 22 member 3	reviewed	-	Slc22a3	Inhibition	-	-	-
Q9WTW5	BXGT021935	Solute carrier family 22 member 3	reviewed	-	Slc22a3	Activity	-	-	-
Q9R0W2	BXGT021408	Solute carrier family 22 member 2	reviewed	-	Slc22a2	Km	'='	172000	nM
Q9R0W2	BXGT021408	Solute carrier family 22 member 2	reviewed	-	Slc22a2	Ki	'='	280000	nM
O75751	BXGT005150	Solute carrier family 22 member 3	reviewed	Transporter	SLC22A3	IC50	'='	2200000	nM
Q9R0W2	BXGT021408	Solute carrier family 22 member 2	reviewed	-	Slc22a2	Km	'='	730000	nM
Q9H015	BXGT020432	Solute carrier family 22 member 4	reviewed	Transporter	SLC22A4	Activity	'='	89	%
Q9Z0E8	BXGT022397	Solute carrier family 22 member 5	reviewed	-	Slc22a5	Activity	-	-	-
Q9R0W2	BXGT021408	Solute carrier family 22 member 2	reviewed	-	Slc22a2	Ki	'='	713600	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	100	%
O15244	BXGT004140	Solute carrier family 22 member 2	reviewed	Transporter	SLC22A2	Activity	-	-	-
Q63089	BXGT016060	Solute carrier family 22 member 1	reviewed	-	Slc22a1	Km	'='	1660000	nM
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	106	%
O70594	BXGT005072	Solute carrier family 22 member 5	reviewed	-	Slc22a5	Activity	-	-	-
Q8TCC7	BXGT018794	Solute carrier family 22 member 8	reviewed	Transporter	SLC22A8	Activity	-	-	-
Q63089	BXGT016060	Solute carrier family 22 member 1	reviewed	-	Slc22a1	Activity	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00076	Loquat	Eriobotrya japonica	Fruits
BXGF00085	Soy bean	Glycine max	Soy
BXGF00105	Apple	Malus pumila	Fruits
BXGF00125	Rice	Oryza sativa	Cereals and cereal products
BXGF00148	Almond	Prunus dulcis	Nuts
BXGF00205	Corn	Zea mays	Cereals and cereal products
BXGF01848	Pyrus pyraster	Pyrus pyraster	Medicinal Plant
BXGF02094	Astragalus oxyphysus	Astragalus oxyphysus	Others
BXGF02497	Hydrodictyon reticulatum	Hydrodictyon reticulatum	Human Edible Plant
BXGF02801	Senecio candollei	Senecio candollei	Others
BXGF02849	Polyscias scutellaria	Polyscias scutellaria	Medicinal Plant
BXGF02871	Centaurea glastifolia	Centaurea glastifolia	Others
BXGF02902	Grindelia havardii	Grindelia havardii	Others
BXGF02918	Nephelium maingayi	Nephelium maingayi	Human Edible Plant
BXGF02934	Galanthus nivalis	Galanthus nivalis	Medicinal Plant
BXGF02954	Euphorbia armena	Euphorbia armena	Others
BXGF03427	Phellodendron chinense	Phellodendron chinense	Medicinal Plant
BXGF06109	Cuscuta reflexa	Cuscuta reflexa	Medicinal Plant
BXGF06113	Plantago depressa	Plantago depressa	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}