Showing entry for Cytokine receptor common subunit beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009681
Protein NameCytokine receptor common subunit beta
Uniport IdP32927
GeneCSF2RB
Gene Id1439
DomainIL6Ra-bind; Interfer-bind
Pfam PF09240   PF09294  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction
4. Cellular Processes 4.2 Cell growth and death hsa04210 Apoptosis
3. Environmental Information Processing 3.2 Signal transduction hsa04630 Jak-STAT signaling pathway
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0044267 cellular protein metabolic process
Biological Process GO:0036016 cellular response to interleukin-3
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0038156 interleukin-3-mediated signaling pathway
Biological Process GO:0038043 interleukin-5-mediated signaling pathway
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0007585 respiratory gaseous exchange by respiratory system
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0007165 signal transduction
molecular function GO:0004896 cytokine receptor activity
molecular function GO:0038023 signaling receptor activity
cellular component GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-392499 Metabolism of proteins
R-HSA-449147 Signaling by Interleukins
R-HSA-449147 Signaling by Interleukins
R-HSA-451927 Interleukin-2 family signaling
R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
R-HSA-5668914 Diseases of metabolism
R-HSA-5673001 RAF/MAP kinase cascade
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5683826 Surfactant metabolism
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-5687613 Diseases associated with surfactant metabolism
R-HSA-5688849 Defective CSF2RB causes SMDP5
R-HSA-5688890 Defective CSF2RA causes SMDP4
R-HSA-912526 Interleukin receptor SHC signaling
R-HSA-9607240 FLT3 Signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0010200 BXGD000653 Coughing Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0013404 BXGD000833 Dyspnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0018621 BXGD001210 Hay fever Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0034050 BXGD002452 Pulmonary Alveolar Proteinosis Respiratory Tract Diseases
C0034642 BXGD002485 Rales Pathological Conditions, Signs and Symptoms
C0035229 BXGD002516 Respiratory Insufficiency Respiratory Tract Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0039231 BXGD002799 Tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0231835 BXGD004527 Tachypnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0476273 BXGD008986 Respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0700292 BXGD009884 Hypoxemia Pathological Conditions, Signs and Symptoms
C1261473 BXGD011855 Sarcoma Neoplasms
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1867873 BXGD016473 Failure to thrive in infancy
C2931035 BXGD017942 Pulmonary alveolar proteinosis, congenital Respiratory Tract Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3277226 BXGD018711 Restrictive ventilatory defect
C3280574 BXGD018845 SURFACTANT METABOLISM DYSFUNCTION, PULMONARY, 5
C4022660 BXGD020947 Autoimmune antibody positivity
C4023112 BXGD021110 Acute infectious pneumonia
C4025279 BXGD021620 Respiratory failure requiring assisted ventilation Respiratory Tract Diseases
C4274391 BXGD022353 Dominant beta-thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4281786 BXGD022416 Presence of foam cells Cardiovascular Diseases
C4476749 BXGD022860 Crazy paving pattern on pulmonary HRCT
C4476917 BXGD022889 Elevated carcinoembryonic antigen level
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018397 beta-1,4-mannan 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein