adisease

Showing entry for Dyspnea

General Disease Information
BXGD Id	BXGD000833
Disease Name	Dyspnea
Disease CUI Id	C0013404
MeSH Codes	C23 C08
Disease Class Name	Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0002086
Human Phenotype Ontology Term	Abnormality of the respiratory system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O95264	BXGT005367	5-hydroxytryptamine receptor 3B	9177	reviewed	Ion channel
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00451	BXGT005545	Coagulation factor VIII	2157	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00736	BXGT005632	Complement C1r subcomponent	715	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01130	BXGT005735	Low-density lipoprotein receptor	3949	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03950	BXGT006116	Angiogenin	283	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P07737	BXGT006663	Profilin-1	5216	reviewed
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09001	BXGT006848	39S ribosomal protein L3, mitochondrial	11222	reviewed
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09467	BXGT006893	Fructose-1,6-bisphosphatase 1	2203	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09651	BXGT006913	Heterogeneous nuclear ribonucleoprotein A1	3178	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10253	BXGT007550	Lysosomal alpha-glucosidase	2548	reviewed	Enzyme
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P14616	BXGT008026	Insulin receptor-related protein	3645	reviewed	Kinase
P14920	BXGT008067	D-amino-acid oxidase	1610	reviewed
P15941	BXGT008176	Mucin-1	4582	reviewed
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18206	BXGT008389	Vinculin	7414	reviewed
P20807	BXGT008601	Calpain-3	825	reviewed	Enzyme
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P22557	BXGT008783	5-aminolevulinate synthase, erythroid-specific, mitochondrial	212	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P32927	BXGT009681	Cytokine receptor common subunit beta	1439	reviewed	Receptor
P35499	BXGT009839	Sodium channel protein type 4 subunit alpha	6329	reviewed	Ion channel
P37023	BXGT009953	Serine/threonine-protein kinase receptor R3	94	reviewed	Kinase
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P48051	BXGT010611	G protein-activated inward rectifier potassium channel 2	3763	reviewed	Ion channel
P49419	BXGT010705	Alpha-aminoadipic semialdehyde dehydrogenase	501	reviewed	Enzyme
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51170	BXGT010843	Amiloride-sensitive sodium channel subunit gamma	6340	reviewed	Ion channel
P51617	BXGT010868	Interleukin-1 receptor-associated kinase 1	3654	reviewed	Kinase
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
P54764	BXGT011078	Ephrin type-A receptor 4	2043	reviewed	Kinase
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P56192	BXGT011149	Methionine--tRNA ligase, cytoplasmic	4141	reviewed
P56470	BXGT011173	Galectin-4	3960	reviewed	Signaling
P56817	BXGT011200	Beta-secretase 1	23621	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P63316	BXGT011517	Troponin C, slow skeletal and cardiac muscles	7134	reviewed	Calcium-binding protein
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P78504	BXGT011844	Protein jagged-1	182	reviewed
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q02487	BXGT012656	Desmocollin-2	1824	reviewed	Cell adhesion
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07001	BXGT012907	Acetylcholine receptor subunit delta	1144	reviewed	Ion channel
Q07820	BXGT012942	Induced myeloid leukemia cell differentiation protein Mcl-1	4170	reviewed	Signaling
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13873	BXGT013398	Bone morphogenetic protein receptor type-2	659	reviewed	Kinase
Q14203	BXGT013455	Dynactin subunit 1	1639	reviewed	Chaperone
Q14315	BXGT013460	Filamin-C	2318	reviewed
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q2TU34	BXGT014223	Fructose-1,6-bisphosphatase 1	2203	unreviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q86TM3	BXGT017607	Probable ATP-dependent RNA helicase DDX53	168400	reviewed
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q8TD43	BXGT018806	Transient receptor potential cation channel subfamily M member 4	54795	reviewed	Ion channel
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q96AT9	BXGT019619	Ribulose-phosphate 3-epimerase	6120	reviewed
Q96PY6	BXGT019712	Serine/threonine-protein kinase Nek1	4750	reviewed	Kinase
Q99581	BXGT019937	Protein FEV	54738	reviewed	Transcription factor
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q99808	BXGT019964	Equilibrative nucleoside transporter 1	2030	reviewed	Transporter
Q9BQP7	BXGT020114	Mitochondrial genome maintenance exonuclease 1	92667	reviewed
Q9BYT8	BXGT020190	Neurolysin, mitochondrial	57486	reviewed	Enzyme
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NQX3	BXGT021172	Gephyrin	10243	reviewed
Q9P2K8	BXGT021302	eIF-2-alpha kinase GCN2	440275	reviewed
Q9UHD2	BXGT021697	Serine/threonine-protein kinase TBK1	29110	reviewed	Kinase
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	10800	reviewed	G-protein coupled receptor
P15509	BXGT022826	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	1438	reviewed	Signaling
Q53GS7	BXGT023762	Nucleoporin GLE1	2733	reviewed	Transporter
Q9H9S5	BXGT024623	Fukutin-related protein	79147	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q9H1K1	BXGT025766	Iron-sulfur cluster assembly enzyme ISCU, mitochondrial	23479	reviewed
Q96RD7	BXGT025890	Pannexin-1	24145	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}