Showing entry for Respiratory Insufficiency


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002516
Disease NameRespiratory Insufficiency
Disease CUI IdC0035229
MeSH Codes C08  
Disease Class NameRespiratory Tract Diseases
Semantic TypePathologic Function
Human Phenotype Ontology Id HP:0002086  
Human Phenotype Ontology TermAbnormality of the respiratory system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00217 BXGT003898 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 4728 reviewed Enzyme
O00469 BXGT003926 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 5352 reviewed Enzyme
O14832 BXGT004104 Phytanoyl-CoA dioxygenase, peroxisomal 5264 reviewed
O15146 BXGT004131 Muscle, skeletal receptor tyrosine-protein kinase 4593 reviewed Kinase
O15239 BXGT004139 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 4694 reviewed
O15357 BXGT004156 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 3636 reviewed
O43181 BXGT004576 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 4724 reviewed
O43676 BXGT004611 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 4709 reviewed
O43766 BXGT004622 Lipoyl synthase, mitochondrial 11019 reviewed
O43772 BXGT004623 Mitochondrial carnitine/acylcarnitine carrier protein 788 reviewed Transporter
O60331 BXGT004872 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 23396 reviewed Kinase
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O75251 BXGT005107 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 374291 reviewed
O75306 BXGT005108 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 4720 reviewed Enzyme
O75369 BXGT005119 Filamin-B 2317 reviewed
O75380 BXGT005120 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 4726 reviewed Enzyme
O75489 BXGT005131 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 4722 reviewed
O94903 BXGT005339 Pyridoxal phosphate homeostasis protein 11212 reviewed
O95169 BXGT005356 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 4714 reviewed Enzyme
O95299 BXGT005372 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial 4705 reviewed Enzyme
O95831 BXGT005399 Apoptosis-inducing factor 1, mitochondrial 9131 reviewed Enzyme
O96000 BXGT005412 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 4716 reviewed
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02533 BXGT005887 Keratin, type I cytoskeletal 14 3861 reviewed
P02538 BXGT005888 Keratin, type II cytoskeletal 6A 3853 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P03886 BXGT006108 NADH-ubiquinone oxidoreductase chain 1 4535 reviewed Enzyme
P03891 BXGT006110 NADH-ubiquinone oxidoreductase chain 2 4536 reviewed
P03897 BXGT006111 NADH-ubiquinone oxidoreductase chain 3 4537 reviewed
P03905 BXGT006113 NADH-ubiquinone oxidoreductase chain 4 4538 reviewed Enzyme
P03915 BXGT006114 NADH-ubiquinone oxidoreductase chain 5 4540 reviewed Enzyme
P03923 BXGT006115 NADH-ubiquinone oxidoreductase chain 6 4541 reviewed
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P06280 BXGT006433 Alpha-galactosidase A 2717 reviewed
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07602 BXGT006646 Prosaposin 5660 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08243 BXGT006755 Asparagine synthetase [glutamine-hydrolyzing] 440 reviewed Enzyme
P08779 BXGT006824 Keratin, type I cytoskeletal 16 3868 reviewed
P10253 BXGT007550 Lysosomal alpha-glucosidase 2548 reviewed Enzyme
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P11230 BXGT007677 Acetylcholine receptor subunit beta 1140 reviewed Ion channel
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12235 BXGT007774 ADP/ATP translocase 1 291 reviewed Transporter
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13647 BXGT007937 Keratin, type II cytoskeletal 5 3852 reviewed
P13716 BXGT007948 Delta-aminolevulinic acid dehydratase 210 reviewed Enzyme
P15104 BXGT008081 Glutamine synthetase 2752 reviewed Enzyme
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P19404 BXGT008477 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 4729 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P22314 BXGT008755 Ubiquitin-like modifier-activating enzyme 1 7317 reviewed Enzyme
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23786 BXGT008906 Carnitine O-palmitoyltransferase 2, mitochondrial 1376 reviewed Enzyme
P24158 BXGT008951 Myeloblastin 5657 reviewed Enzyme
P28329 BXGT009251 Choline O-acetyltransferase 1103 reviewed Enzyme
P28331 BXGT009252 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4719 reviewed Enzyme
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P31327 BXGT009523 Carbamoyl-phosphate synthase [ammonia], mitochondrial 1373 reviewed Enzyme
P32927 BXGT009681 Cytokine receptor common subunit beta 1439 reviewed Receptor
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35499 BXGT009839 Sodium channel protein type 4 subunit alpha 6329 reviewed Ion channel
P42702 BXGT010335 Leukemia inhibitory factor receptor 3977 reviewed Signaling
P43155 BXGT010363 Carnitine O-acetyltransferase 1384 reviewed Enzyme
P48051 BXGT010611 G protein-activated inward rectifier potassium channel 2 3763 reviewed Ion channel
P49821 BXGT010748 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 4723 reviewed
P49917 BXGT010765 DNA ligase 4 3981 reviewed
P50542 BXGT010808 Peroxisomal targeting signal 1 receptor 5830 reviewed Transporter
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P56192 BXGT011149 Methionine--tRNA ligase, cytoplasmic 4141 reviewed
P56556 BXGT011179 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 4700 reviewed Enzyme
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P60891 BXGT011337 Ribose-phosphate pyrophosphokinase 1 5631 reviewed Kinase
P68133 BXGT011578 Actin, alpha skeletal muscle 58 reviewed Cellular structure
P78508 BXGT011845 ATP-sensitive inward rectifier potassium channel 10 3766 reviewed Ion channel
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q02809 BXGT012674 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 5351 reviewed Enzyme
Q04771 BXGT012783 Activin receptor type-1 90 reviewed Kinase
Q04844 BXGT012789 Acetylcholine receptor subunit epsilon 1145 reviewed Ion channel
Q07001 BXGT012907 Acetylcholine receptor subunit delta 1144 reviewed Ion channel
Q13510 BXGT013367 Acid ceramidase 427 reviewed Enzyme
Q13698 BXGT013392 Voltage-dependent L-type calcium channel subunit alpha-1S 779 reviewed Ion channel
Q14203 BXGT013455 Dynactin subunit 1 1639 reviewed Chaperone
Q14315 BXGT013460 Filamin-C 2318 reviewed
Q15031 BXGT013525 Probable leucine--tRNA ligase, mitochondrial 23395 reviewed Enzyme
Q15067 BXGT013532 Peroxisomal acyl-coenzyme A oxidase 1 51 reviewed Enzyme
Q16795 BXGT013671 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 4704 reviewed Enzyme
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q6NUK1 BXGT016429 Calcium-binding mitochondrial carrier protein SCaMC-1 29957 reviewed Transporter
Q6NVY1 BXGT016432 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial 26275 reviewed Enzyme
Q7LG56 BXGT016999 Ribonucleoside-diphosphate reductase subunit M2 B 50484 reviewed Enzyme
Q86Y39 BXGT017632 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 126328 reviewed
Q8N183 BXGT018497 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 91942 reviewed
Q8NBL1 BXGT018539 Protein O-glucosyltransferase 1 56983 reviewed
Q8NCM8 BXGT018548 Cytoplasmic dynein 2 heavy chain 1 79659 reviewed Enzyme
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q96RQ3 BXGT019732 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial 56922 reviewed Enzyme
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q99986 BXGT019980 Serine/threonine-protein kinase VRK1 7443 reviewed Kinase
Q9BQP7 BXGT020114 Mitochondrial genome maintenance exonuclease 1 92667 reviewed
Q9BU61 BXGT020131 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 25915 reviewed
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9HCC0 BXGT020530 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial 64087 reviewed Enzyme
Q9NSD9 BXGT021206 Phenylalanine--tRNA ligase beta subunit 10056 reviewed Enzyme
Q9NX14 BXGT021242 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 54539 reviewed Enzyme
Q9P032 BXGT021286 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 29078 reviewed
Q9UBK8 BXGT021655 Methionine synthase reductase 4552 reviewed
Q9UHD8 BXGT021698 Septin-9 10801 reviewed Enzyme modulator
Q9Y263 BXGT022220 Phospholipase A-2-activating protein 9373 reviewed Enzyme modulator
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
Q9Y375 BXGT022253 Complex I intermediate-associated protein 30, mitochondrial 51103 reviewed
Q9Y6M9 BXGT022336 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 4715 reviewed Enzyme
P20036 BXGT022764 HLA class II histocompatibility antigen, DP alpha 1 chain 3113 reviewed Immune response
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
O75208 BXGT023882 Ubiquinone biosynthesis protein COQ9, mitochondrial 57017 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
Q9H9S5 BXGT024623 Fukutin-related protein 79147 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q9BYC5 BXGT025656 Alpha-(1,6)-fucosyltransferase 2530 reviewed
Q96MF2 BXGT025769 SH3 and cysteine-rich domain-containing protein 3 246329 reviewed
P61916 BXGT025881 NPC intracellular cholesterol transporter 2 10577 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease