Showing entry for Cervical Squamous Cell Carcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006677
Disease NameCervical Squamous Cell Carcinoma
Disease CUI IdC0279671
MeSH Codes C04   C13  
Disease Class NameNeoplasms; Female Urogenital Diseases and Pregnancy Complications
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O43772 BXGT004623 Mitochondrial carnitine/acylcarnitine carrier protein 788 reviewed Transporter
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75340 BXGT005112 Programmed cell death protein 6 10016 reviewed
O75676 BXGT005144 Ribosomal protein S6 kinase alpha-4 8986 reviewed Kinase
O95235 BXGT005360 Kinesin-like protein KIF20A 10112 reviewed Cellular structure
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02533 BXGT005887 Keratin, type I cytoskeletal 14 3861 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P05787 BXGT006385 Keratin, type II cytoskeletal 8 3856 reviewed
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08047 BXGT006720 Transcription factor Sp1 6667 reviewed Nucleic acid binding
P08133 BXGT006727 Annexin A6 309 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08670 BXGT006810 Vimentin 7431 reviewed
P08758 BXGT006821 Annexin A5 308 reviewed
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P11142 BXGT007658 Heat shock cognate 71 kDa protein 3312 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12277 BXGT007789 Creatine kinase B-type 1152 reviewed Kinase
P12830 BXGT007852 Cadherin-1 999 reviewed
P13647 BXGT007937 Keratin, type II cytoskeletal 5 3852 reviewed
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15328 BXGT008108 Folate receptor alpha 2348 reviewed
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15907 BXGT008168 Beta-galactoside alpha-2,6-sialyltransferase 1 6480 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16333 BXGT008219 Cytoplasmic protein NCK1 4690 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20711 BXGT008594 Aromatic-L-amino-acid decarboxylase 1644 reviewed
P20933 BXGT008618 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase 175 reviewed Enzyme
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P30101 BXGT009402 Protein disulfide-isomerase A3 2923 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P32927 BXGT009681 Cytokine receptor common subunit beta 1439 reviewed Receptor
P33316 BXGT009715 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial 1854 reviewed Enzyme
P34913 BXGT009770 Bifunctional epoxide hydrolase 2 2053 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35442 BXGT009832 Thrombospondin-2 7058 reviewed
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35613 BXGT009856 Basigin 682 reviewed
P36551 BXGT009927 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1371 reviewed Enzyme
P40261 BXGT010170 Nicotinamide N-methyltransferase 4837 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41143 BXGT010223 Delta-type opioid receptor 4985 reviewed G-protein coupled receptor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49711 BXGT010728 Transcriptional repressor CTCF 10664 reviewed Transcription factor
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P51790 BXGT010890 H(+)/Cl(-) exchange transporter 3 1182 reviewed Ion channel
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61019 BXGT011348 Ras-related protein Rab-2A 5862 reviewed
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q06710 BXGT012887 Paired box protein Pax-8 7849 reviewed
Q07021 BXGT012915 Complement component 1 Q subcomponent-binding protein, mitochondrial 708 reviewed
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q08945 BXGT013014 FACT complex subunit SSRP1 6749 reviewed
Q11201 BXGT013217 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 6482 reviewed
Q11203 BXGT013218 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 6487 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13464 BXGT013357 Rho-associated protein kinase 1 6093 reviewed Kinase
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13882 BXGT013399 Protein-tyrosine kinase 6 5753 reviewed Kinase
Q13887 BXGT013401 Krueppel-like factor 5 688 reviewed Nucleic acid binding
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14527 BXGT013479 Helicase-like transcription factor 6596 reviewed
Q14573 BXGT013486 Inositol 1,4,5-trisphosphate receptor type 3 3710 reviewed Ion channel
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15758 BXGT013594 Neutral amino acid transporter B(0) 6510 reviewed Transporter
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16674 BXGT013655 Melanoma-derived growth regulatory protein 8190 reviewed
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q86TM3 BXGT017607 Probable ATP-dependent RNA helicase DDX53 168400 reviewed
Q92843 BXGT019384 Bcl-2-like protein 2 599 reviewed Signaling
Q96GD0 BXGT019665 Pyridoxal phosphate phosphatase 57026 reviewed Enzyme
Q96T88 BXGT019747 E3 ubiquitin-protein ligase UHRF1 29128 reviewed
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q9C005 BXGT020207 Protein dpy-30 homolog 84661 reviewed
Q9C098 BXGT020208 Serine/threonine-protein kinase DCLK3 85443 reviewed Kinase
Q9C0B1 BXGT020209 Alpha-ketoglutarate-dependent dioxygenase FTO 79068 reviewed
Q9NR28 BXGT021178 Diablo homolog, mitochondrial 56616 reviewed
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NZ08 BXGT021266 Endoplasmic reticulum aminopeptidase 1 51752 reviewed Enzyme
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBE8 BXGT021652 Serine/threonine-protein kinase NLK 51701 reviewed Kinase
Q9UBZ9 BXGT021666 DNA repair protein REV1 51455 reviewed
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9UJW3 BXGT021732 DNA (cytosine-5)-methyltransferase 3-like 29947 reviewed
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y5W5 BXGT022303 Wnt inhibitory factor 1 11197 reviewed Calcium-binding protein
Q9Y6Q9 BXGT022338 Nuclear receptor coactivator 3 8202 reviewed Kinase
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P19235 BXGT022895 Erythropoietin receptor 2057 reviewed Receptor
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
Q7L8A9 BXGT025010 Tubulinyl-Tyr carboxypeptidase 1 22846 reviewed
Q9UGM3 BXGT025543 Deleted in malignant brain tumors 1 protein 1755 reviewed Enzyme
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
Q7Z628 BXGT026116 Neuroepithelial cell-transforming gene 1 protein 10276 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease