Showing entry for Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009715
Protein NameDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Uniport IdP33316
GeneDUT
Gene Id1854
DomaindUTPase
Pfam PF00692  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00240 Pyrimidine metabolism
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006260 DNA replication
Biological Process GO:0006226 dUMP biosynthetic process
Biological Process GO:0046081 dUTP catabolic process
Biological Process GO:0006139 nucleobase-containing compound metabolic process
Biological Process GO:0015949 nucleobase-containing small molecule interconversion
molecular function GO:0004170 dUTP diphosphatase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0003723 RNA binding
cellular component GO:0070062 extracellular exosome
cellular component GO:0005739 mitochondrion
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004114 BXGD000255 Astrocytoma Neoplasms
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0010678 BXGD000684 Cysticercosis Infections
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015674 BXGD001012 Chronic Fatigue Syndrome Infections; Musculoskeletal Diseases; Nervous System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030312 BXGD002207 Pancytopenia Hemic and Lymphatic Diseases
C0033839 BXGD002434 Pseudorabies Infections; Nervous System Diseases; Animal Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0037290 BXGD002683 Skin Pigmentation
C0041296 BXGD002903 Tuberculosis Infections
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0206186 BXGD004172 Leukoplakia, Hairy Pathological Conditions, Signs and Symptoms; Neoplasms; Infections; Stomatognathic Diseases
C0206708 BXGD004256 Cervical Intraepithelial Neoplasia Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0343641 BXGD007636 Human papilloma virus infection Infections
C0574785 BXGD009506 Lower Urinary Tract Symptoms Pathological Conditions, Signs and Symptoms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0679427 BXGD009777 myeloblastosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0851140 BXGD010916 Carcinoma in situ of uterine cervix Neoplasms
C0940937 BXGD011490 precancerous lesions
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4554010 BXGD023556 Isomerism (body) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases; Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein