adisease

Showing entry for Fatigue

General Disease Information
BXGD Id	BXGD001011
Disease Name	Fatigue
Disease CUI Id	C0015672
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0025142
Human Phenotype Ontology Term	Constitutional symptom
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
A4D126	BXGT001208	D-ribitol-5-phosphate cytidylyltransferase	729920	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00255	BXGT003903	Menin	4221	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O00522	BXGT003935	Krev interaction trapped protein 1	889	reviewed
O14980	BXGT004119	Exportin-1	7514	reviewed	Receptor
O15146	BXGT004131	Muscle, skeletal receptor tyrosine-protein kinase	4593	reviewed	Kinase
O15178	BXGT004135	T-box transcription factor T	6862	reviewed	Transcription factor
O15379	BXGT004159	Histone deacetylase 3	8841	reviewed	Epigenetic regulator
O15439	BXGT004169	Multidrug resistance-associated protein 4	10257	reviewed	Transporter
O15553	BXGT004181	Pyrin	4210	reviewed
O43181	BXGT004576	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	4724	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O43708	BXGT004617	Maleylacetoacetate isomerase	2954	reviewed
O43776	BXGT004624	Asparagine--tRNA ligase, cytoplasmic	4677	reviewed	Enzyme
O43915	BXGT004636	Vascular endothelial growth factor D	2277	reviewed	Signaling
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O60840	BXGT004901	Voltage-dependent L-type calcium channel subunit alpha-1F	778	reviewed	Ion channel
O60858	BXGT004903	E3 ubiquitin-protein ligase TRIM13	10206	reviewed
O75390	BXGT005123	Citrate synthase, mitochondrial	1431	reviewed	Enzyme
O75628	BXGT005140	GTP-binding protein REM 1	28954	reviewed
O75923	BXGT005166	Dysferlin	8291	reviewed	Transporter
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
O95263	BXGT005366	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	8622	reviewed
P00374	BXGT005520	Dihydrofolate reductase	1719	reviewed	Enzyme
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00709	BXGT005621	Alpha-lactalbumin	3906	reviewed
P00746	BXGT005638	Complement factor D	1675	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02144	BXGT005853	Myoglobin	4151	reviewed
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02652	BXGT005910	Apolipoprotein A-II	336	reviewed	Transporter
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02743	BXGT005937	Serum amyloid P-component	325	reviewed
P02760	BXGT005948	Protein AMBP	259	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P02792	BXGT005966	Ferritin light chain	2512	reviewed	Storage
P02818	BXGT005969	Osteocalcin	632	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P03950	BXGT006116	Angiogenin	283	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04732	BXGT006252	Metallothionein-1E	4493	reviewed
P04745	BXGT006255	Alpha-amylase 1	278	reviewed
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P05155	BXGT006328	Plasma protease C1 inhibitor	710	reviewed	Enzyme modulator
P05156	BXGT006329	Complement factor I	3426	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P06756	BXGT006499	Integrin alpha-V	3685	reviewed
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07108	BXGT006551	Acyl-CoA-binding protein	1622	reviewed	Enzyme modulator
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07237	BXGT006576	Protein disulfide-isomerase	5034	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07332	BXGT006601	Tyrosine-protein kinase Fes/Fps	2242	reviewed	Kinase
P07451	BXGT006627	Carbonic anhydrase 3	761	reviewed
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P07737	BXGT006663	Profilin-1	5216	reviewed
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08185	BXGT006742	Corticosteroid-binding globulin	866	reviewed	Enzyme modulator
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08588	BXGT006795	Beta-1 adrenergic receptor	153	reviewed	G-protein coupled receptor
P08603	BXGT006798	Complement factor H	3075	reviewed
P08648	BXGT006804	Integrin alpha-5	3678	reviewed
P08708	BXGT006817	40S ribosomal protein S17	6218	reviewed	Nucleic acid binding
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P09651	BXGT006913	Heterogeneous nuclear ribonucleoprotein A1	3178	reviewed
P09884	BXGT006937	DNA polymerase alpha catalytic subunit	5422	reviewed
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P0DP23	BXGT007520	Calmodulin-1	808	reviewed
P0DP24	BXGT007521	Calmodulin-2	808	reviewed
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10276	BXGT007553	Retinoic acid receptor alpha	5914	reviewed	Nuclear receptor
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11217	BXGT007674	Glycogen phosphorylase, muscle form	5837	reviewed	Enzyme
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11766	BXGT007745	Alcohol dehydrogenase class-3	128	reviewed	Enzyme
P11802	BXGT007750	Cyclin-dependent kinase 4	1019	reviewed	Kinase
P11912	BXGT007758	B-cell antigen receptor complex-associated protein alpha chain	973	reviewed	Receptor
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13688	BXGT007943	Carcinoembryonic antigen-related cell adhesion molecule 1	634	reviewed
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	210	reviewed	Enzyme
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14672	BXGT008037	Solute carrier family 2, facilitated glucose transporter member 4	6517	reviewed	Transporter
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P14920	BXGT008067	D-amino-acid oxidase	1610	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15086	BXGT008078	Carboxypeptidase B	1360	reviewed	Enzyme
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15735	BXGT008151	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	5261	reviewed	Kinase
P15814	BXGT008159	Immunoglobulin lambda-like polypeptide 1	3543	reviewed
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P15941	BXGT008176	Mucin-1	4582	reviewed
P16070	BXGT008186	CD44 antigen	960	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P17612	BXGT008322	cAMP-dependent protein kinase catalytic subunit alpha	5566	reviewed	Kinase
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P19021	BXGT008449	Peptidyl-glycine alpha-amidating monooxygenase	5066	reviewed	Enzyme
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19429	BXGT008479	Troponin I, cardiac muscle	7137	reviewed	Cellular structure
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19440	BXGT008481	Glutathione hydrolase 1 proenzyme	2678	reviewed	Enzyme
P19623	BXGT008503	Spermidine synthase	6723	reviewed	Enzyme
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22304	BXGT008752	Iduronate 2-sulfatase	3423	reviewed
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	54658	reviewed
P22557	BXGT008783	5-aminolevulinate synthase, erythroid-specific, mitochondrial	212	reviewed	Enzyme
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P23246	BXGT008840	Splicing factor, proline- and glutamine-rich	6421	reviewed	Nucleic acid binding
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25929	BXGT009078	Neuropeptide Y receptor type 1	4886	reviewed	G-protein coupled receptor
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P30536	BXGT009435	Translocator protein	706	reviewed
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P33316	BXGT009715	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial	1854	reviewed	Enzyme
P33981	BXGT009744	Dual specificity protein kinase TTK	7272	reviewed	Kinase
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35475	BXGT009837	Alpha-L-iduronidase	3425	reviewed	Enzyme
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P35914	BXGT009880	Hydroxymethylglutaryl-CoA lyase, mitochondrial	3155	reviewed	Enzyme
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36894	BXGT009939	Bone morphogenetic protein receptor type-1A	657	reviewed	Kinase
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40926	BXGT010207	Malate dehydrogenase, mitochondrial	4191	reviewed	Enzyme
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41143	BXGT010223	Delta-type opioid receptor	4985	reviewed	G-protein coupled receptor
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P41222	BXGT010237	Prostaglandin-H2 D-isomerase	5730	reviewed	Enzyme
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P41594	BXGT010266	Metabotropic glutamate receptor 5	2915	reviewed	G-protein coupled receptor
P42226	BXGT010288	Signal transducer and activator of transcription 6	6778	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42766	BXGT010337	60S ribosomal protein L35	11224	reviewed	Nucleic acid binding
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P45985	BXGT010496	Dual specificity mitogen-activated protein kinase kinase 4	6416	reviewed	Kinase
P46019	BXGT010498	Phosphorylase b kinase regulatory subunit alpha, liver isoform	5256	reviewed	Kinase
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P47900	BXGT010595	P2Y purinoceptor 1	5028	reviewed	G-protein coupled receptor
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48728	BXGT010654	Aminomethyltransferase, mitochondrial	275	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49023	BXGT010672	Paxillin	5829	reviewed	Cellular structure
P49638	BXGT010720	Alpha-tocopherol transfer protein	7274	reviewed	Transporter
P50416	BXGT010797	Carnitine O-palmitoyltransferase 1, liver isoform	1374	reviewed	Enzyme
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51170	BXGT010843	Amiloride-sensitive sodium channel subunit gamma	6340	reviewed	Ion channel
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P52701	BXGT010943	DNA mismatch repair protein Msh6	2956	reviewed	Nucleic acid binding
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
P53396	BXGT010988	ATP-citrate synthase	47	reviewed	Enzyme
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54278	BXGT011038	Mismatch repair endonuclease PMS2	5395	reviewed	Nucleic acid binding
P54646	BXGT011062	5'-AMP-activated protein kinase catalytic subunit alpha-2	5563	reviewed	Kinase
P54764	BXGT011078	Ephrin type-A receptor 4	2043	reviewed	Kinase
P54829	BXGT011085	Tyrosine-protein phosphatase non-receptor type 5	84867	reviewed
P54886	BXGT011092	Delta-1-pyrroline-5-carboxylate synthase	5832	reviewed	Enzyme
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P55957	BXGT011137	BH3-interacting domain death agonist	637	reviewed
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60981	BXGT011344	Destrin	11034	reviewed
P61981	BXGT011400	14-3-3 protein gamma	7532	reviewed	Chaperone
P62857	BXGT011466	40S ribosomal protein S28	6234	reviewed	Nucleic acid binding
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P63316	BXGT011517	Troponin C, slow skeletal and cardiac muscles	7134	reviewed	Calcium-binding protein
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P78310	BXGT011830	Coxsackievirus and adenovirus receptor	1525	reviewed
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q01082	BXGT012567	Spectrin beta chain, non-erythrocytic 1	6711	reviewed
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q01831	BXGT012621	DNA repair protein complementing XP-C cells	7508	reviewed	Nucleic acid binding
Q02241	BXGT012644	Kinesin-like protein KIF23	9493	reviewed	Cellular structure
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q05516	BXGT012822	Zinc finger and BTB domain-containing protein 16	7704	reviewed	Transcription factor
Q05823	BXGT012840	2-5A-dependent ribonuclease	6041	reviewed	Kinase
Q05940	BXGT012846	Synaptic vesicular amine transporter	6571	reviewed	Transporter
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q06710	BXGT012887	Paired box protein Pax-8	7849	reviewed
Q07001	BXGT012907	Acetylcholine receptor subunit delta	1144	reviewed	Ion channel
Q07020	BXGT012914	60S ribosomal protein L18	6141	reviewed	Nucleic acid binding
Q07021	BXGT012915	Complement component 1 Q subcomponent-binding protein, mitochondrial	708	reviewed
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q07837	BXGT012943	Neutral and basic amino acid transport protein rBAT	6519	reviewed	Transporter
Q12866	BXGT013273	Tyrosine-protein kinase Mer	10461	reviewed	Kinase
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13489	BXGT013364	Baculoviral IAP repeat-containing protein 3	330	reviewed	Enzyme modulator
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13976	BXGT013409	cGMP-dependent protein kinase 1	5592	reviewed	Kinase
Q14004	BXGT013435	Cyclin-dependent kinase 13	8621	reviewed	Kinase
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14203	BXGT013455	Dynactin subunit 1	1639	reviewed	Chaperone
Q14994	BXGT013519	Nuclear receptor subfamily 1 group I member 3	9970	reviewed	Nuclear receptor
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15149	BXGT013547	Plectin	5339	reviewed	Cellular structure
Q15256	BXGT013553	Receptor-type tyrosine-protein phosphatase R	5801	reviewed
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16512	BXGT013631	Serine/threonine-protein kinase N1	5585	reviewed	Kinase
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16568	BXGT013640	Cocaine- and amphetamine-regulated transcript protein	9607	reviewed
Q2M385	BXGT014131	Macrophage-expressed gene 1 protein	219972	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q59FK2	BXGT015276	Selenocysteine lyase variant	51540	unreviewed
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q658P3	BXGT016142	Metalloreductase STEAP3	55240	reviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q6NYC1	BXGT016436	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	23210	reviewed	Receptor
Q7LG56	BXGT016999	Ribonucleoside-diphosphate reductase subunit M2 B	50484	reviewed	Enzyme
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8N159	BXGT018496	N-acetylglutamate synthase, mitochondrial	162417	reviewed
Q8NCC3	BXGT018546	Group XV phospholipase A2	23659	reviewed	Enzyme
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q8WVQ1	BXGT018996	Soluble calcium-activated nucleotidase 1	124583	reviewed
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q8WZA1	BXGT019024	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	55624	reviewed
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	1244	reviewed	Transporter
Q969Q1	BXGT019610	E3 ubiquitin-protein ligase TRIM63	84676	reviewed
Q96AT9	BXGT019619	Ribulose-phosphate 3-epimerase	6120	reviewed
Q96BI3	BXGT019623	Gamma-secretase subunit APH-1A	51107	reviewed	Enzyme modulator
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96EN8	BXGT019649	Molybdenum cofactor sulfurase	55034	reviewed
Q96I15	BXGT019674	Selenocysteine lyase	51540	reviewed	Enzyme
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q96PY6	BXGT019712	Serine/threonine-protein kinase Nek1	4750	reviewed	Kinase
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99527	BXGT019930	G-protein coupled estrogen receptor 1	2852	reviewed	G-protein coupled receptor
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BUF5	BXGT020135	Tubulin beta-6 chain	84617	reviewed	Cellular structure
Q9BY08	BXGT020177	Emopamil-binding protein-like	84650	reviewed	Enzyme
Q9BYT8	BXGT020190	Neurolysin, mitochondrial	57486	reviewed	Enzyme
Q9C000	BXGT020206	NACHT, LRR and PYD domains-containing protein 1	22861	reviewed
Q9H227	BXGT020447	Cytosolic beta-glucosidase	57733	reviewed	Enzyme
Q9H251	BXGT020449	Cadherin-23	64072	reviewed
Q9HC97	BXGT020527	G-protein coupled receptor 35	2859	reviewed	G-protein coupled receptor
Q9HCR9	BXGT020537	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	50940	reviewed
Q9NR19	BXGT021175	Acetyl-coenzyme A synthetase, cytoplasmic	55902	reviewed	Enzyme
Q9NR56	BXGT021179	Muscleblind-like protein 1	4154	reviewed	Nucleic acid binding
Q9NTG7	BXGT021211	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	23410	reviewed	Epigenetic regulator
Q9NYB5	BXGT021255	Solute carrier organic anion transporter family member 1C1	53919	reviewed	Transporter
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UDY8	BXGT021670	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	10892	reviewed	Enzyme
Q9UGM6	BXGT021687	Tryptophan--tRNA ligase, mitochondrial	10352	reviewed
Q9UHC3	BXGT021695	Acid-sensing ion channel 3	9311	reviewed	Ion channel
Q9UHD2	BXGT021697	Serine/threonine-protein kinase TBK1	29110	reviewed	Kinase
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9ULC6	BXGT021759	Protein-arginine deiminase type-1	29943	reviewed
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9Y275	BXGT022223	Tumor necrosis factor ligand superfamily member 13B	10673	reviewed
Q9Y2M0	BXGT022241	Fanconi-associated nuclease 1	22909	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y478	BXGT022271	5'-AMP-activated protein kinase subunit beta-1	5564	reviewed	Kinase
Q9Y4U1	BXGT022285	Methylmalonic aciduria and homocystinuria type C protein	25974	reviewed
Q9Y5K2	BXGT022293	Kallikrein-4	9622	reviewed	Enzyme
Q9Y5L0	BXGT022296	Transportin-3	23534	reviewed	Transporter
Q9Y5X9	BXGT022307	Endothelial lipase	9388	reviewed	Enzyme
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
Q16134	BXGT022664	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	2110	reviewed	Enzyme
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
Q7Z624	BXGT022792	Calmodulin-lysine N-methyltransferase	79823	reviewed
P26045	BXGT022810	Tyrosine-protein phosphatase non-receptor type 3	5774	reviewed
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
Q9UNS1	BXGT022882	Protein timeless homolog	8914	reviewed
P19235	BXGT022895	Erythropoietin receptor	2057	reviewed	Receptor
Q9UK05	BXGT023094	Growth/differentiation factor 2	2658	reviewed	Signaling
P17752	BXGT023118	Tryptophan 5-hydroxylase 1	7166	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
Q9UBP0	BXGT023601	Spastin	6683	reviewed	Cellular structure
Q53GS7	BXGT023762	Nucleoporin GLE1	2733	reviewed	Transporter
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
P29590	BXGT024350	Protein PML	5371	reviewed
P0DP25	BXGT024595	Calmodulin-3	808	reviewed
Q9Y4W6	BXGT025025	AFG3-like protein 2	10939	reviewed	Enzyme
Q14980	BXGT025336	Nuclear mitotic apparatus protein 1	4926	reviewed
P27918	BXGT025485	Properdin	5199	reviewed
P28715	BXGT025675	DNA repair protein complementing XP-G cells	2073	reviewed
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}