adisease

Showing entry for Pancytopenia

General Disease Information
BXGD Id	BXGD002207
Disease Name	Pancytopenia
Disease CUI Id	C0030312
MeSH Codes	C15
Disease Class Name	Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001871
Human Phenotype Ontology Term	Abnormality of blood and blood-forming tissues
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14773	BXGT004096	Tripeptidyl-peptidase 1	1200	reviewed	Enzyme
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O15245	BXGT004141	Solute carrier family 22 member 1	6580	reviewed	Transporter
O43318	BXGT004586	Mitogen-activated protein kinase kinase kinase 7	6885	reviewed	Kinase
O43683	BXGT004614	Mitotic checkpoint serine/threonine-protein kinase BUB1	699	reviewed	Kinase
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60858	BXGT004903	E3 ubiquitin-protein ligase TRIM13	10206	reviewed
P00374	BXGT005520	Dihydrofolate reductase	1719	reviewed	Enzyme
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05165	BXGT006334	Propionyl-CoA carboxylase alpha chain, mitochondrial	5095	reviewed	Enzyme
P05166	BXGT006335	Propionyl-CoA carboxylase beta chain, mitochondrial	5096	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06744	BXGT006494	Glucose-6-phosphate isomerase	2821	reviewed	Enzyme
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08514	BXGT006781	Integrin alpha-IIb	3674	reviewed
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10276	BXGT007553	Retinoic acid receptor alpha	5914	reviewed	Nuclear receptor
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11586	BXGT007723	C-1-tetrahydrofolate synthase, cytoplasmic	4522	reviewed	Enzyme
P11766	BXGT007745	Alcohol dehydrogenase class-3	128	reviewed	Enzyme
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P15813	BXGT008158	Antigen-presenting glycoprotein CD1d	912	reviewed
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P20062	BXGT008543	Transcobalamin-2	6948	reviewed
P22033	BXGT008721	Methylmalonyl-CoA mutase, mitochondrial	4594	reviewed	Enzyme
P22304	BXGT008752	Iduronate 2-sulfatase	3423	reviewed
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24557	BXGT008976	Thromboxane-A synthase	6916	reviewed
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P26951	BXGT009147	Interleukin-3 receptor subunit alpha	3563	reviewed	Signaling
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30626	BXGT009450	Sorcin	6717	reviewed
P33316	BXGT009715	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial	1854	reviewed	Enzyme
P35579	BXGT009852	Myosin-9	4627	reviewed
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P38571	BXGT010054	Lysosomal acid lipase/cholesteryl ester hydrolase	3988	reviewed	Enzyme
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P40225	BXGT010168	Thrombopoietin	7066	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41212	BXGT010235	Transcription factor ETV6	2120	reviewed	Transcription factor
P41222	BXGT010237	Prostaglandin-H2 D-isomerase	5730	reviewed	Enzyme
P43489	BXGT010394	Tumor necrosis factor receptor superfamily member 4	7293	reviewed
P48729	BXGT010655	Casein kinase I isoform alpha	1452	reviewed	Kinase
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P51159	BXGT010839	Ras-related protein Rab-27A	5873	reviewed
P51580	BXGT010864	Thiopurine S-methyltransferase	7172	reviewed
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61011	BXGT011346	Signal recognition particle 54 kDa protein	6729	reviewed	Nucleic acid binding
P78310	BXGT011830	Coxsackievirus and adenovirus receptor	1525	reviewed
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q01081	BXGT012566	Splicing factor U2AF 35 kDa subunit	7307	reviewed
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q05516	BXGT012822	Zinc finger and BTB domain-containing protein 16	7704	reviewed	Transcription factor
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q08881	BXGT013012	Tyrosine-protein kinase ITK/TSK	3702	reviewed	Kinase
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13426	BXGT013353	DNA repair protein XRCC4	7518	reviewed
Q13535	BXGT013370	Serine/threonine-protein kinase ATR	545	reviewed	Kinase
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q13574	BXGT013379	Diacylglycerol kinase zeta	8525	reviewed	Enzyme
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14191	BXGT013452	Werner syndrome ATP-dependent helicase	7486	reviewed	Enzyme
Q14994	BXGT013519	Nuclear receptor subfamily 1 group I member 3	9970	reviewed	Nuclear receptor
Q15631	BXGT013585	Translin	7247	reviewed
Q15796	BXGT013599	Mothers against decapentaplegic homolog 2	4087	reviewed	Transcription factor
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q16568	BXGT013640	Cocaine- and amphetamine-regulated transcript protein	9607	reviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q8IYD8	BXGT018367	Fanconi anemia group M protein	57697	reviewed	Enzyme
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q8TEK3	BXGT018822	Histone-lysine N-methyltransferase, H3 lysine-79 specific	84444	reviewed	Epigenetic regulator
Q92956	BXGT019399	Tumor necrosis factor receptor superfamily member 14	8764	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96EN8	BXGT019649	Molybdenum cofactor sulfurase	55034	reviewed
Q96EY8	BXGT019655	Corrinoid adenosyltransferase	326625	reviewed	Enzyme
Q96J02	BXGT019679	E3 ubiquitin-protein ligase Itchy homolog	83737	reviewed	Enzyme
Q9BQ15	BXGT020106	SOSS complex subunit B1	79035	reviewed	Nucleic acid binding
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9NPD8	BXGT021152	Ubiquitin-conjugating enzyme E2 T	29089	reviewed
Q9NPI8	BXGT021161	Fanconi anemia group F protein	2188	reviewed
Q9NSD9	BXGT021206	Phenylalanine--tRNA ligase beta subunit	10056	reviewed	Enzyme
Q9NW38	BXGT021230	E3 ubiquitin-protein ligase FANCL	55120	reviewed	Enzyme
Q9UI95	BXGT021714	Mitotic spindle assembly checkpoint protein MAD2B	10459	reviewed
Q9UKV0	BXGT021750	Histone deacetylase 9	9734	reviewed	Epigenetic regulator
Q96C86	BXGT022803	m7GpppX diphosphatase	28960	reviewed	Enzyme
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P29590	BXGT024350	Protein PML	5371	reviewed
P20809	BXGT025043	Interleukin-11	3589	reviewed
Q14980	BXGT025336	Nuclear mitotic apparatus protein 1	4926	reviewed
P62263	BXGT026033	40S ribosomal protein S14	6208	reviewed	Nucleic acid binding

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}