Showing entry for Ran-specific GTPase-activating protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010393
Protein NameRan-specific GTPase-activating protein
Uniport IdP43487
GeneRANBP1
Gene Id5902
DomainRan_BP1
Pfam PF00638  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
6. Human Diseases 6.1 Cancers: Overview hsa05203 Viral carcinogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046907 intracellular transport
Biological Process GO:0046604 positive regulation of mitotic centrosome separation
Biological Process GO:0007165 signal transduction
Biological Process GO:0016032 viral process
molecular function GO:0045296 cadherin binding
molecular function GO:0005092 GDP-dissociation inhibitor activity
molecular function GO:0005096 GTPase activator activity
molecular function GO:0008536 Ran GTPase binding
cellular component GO:0005813 centrosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005635 nuclear envelope
cellular component GO:0005643 nuclear pore
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-162587 HIV Life Cycle
R-HSA-162599 Late Phase of HIV Life Cycle
R-HSA-162906 HIV Infection
R-HSA-162909 Host Interactions of HIV factors
R-HSA-1643685 Disease
R-HSA-165054 Rev-mediated nuclear export of HIV RNA
R-HSA-177243 Interactions of Rev with host cellular proteins
R-HSA-5663205 Infectious disease
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0012236 BXGD000772 DiGeorge Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0149940 BXGD003391 Sciatic Neuropathy Nervous System Diseases
C0220704 BXGD004327 Shprintzen syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1321551 BXGD012436 Shprintzen-Goldberg syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1836929 BXGD014180 Emanuel syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases; Behavior and Behavior Mechanisms; Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3150966 BXGD018365 Supernumerary der(22)t(8;22) syndrome
C4505456 BXGD022964 HIV Coinfection Infections; Immune System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002616 Copper 63.55
BXGC0002953 2-Phenethyl isothiocyanate 163.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein