Showing entry for Sciatic Neuropathy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003391
Disease NameSciatic Neuropathy
Disease CUI IdC0149940
MeSH Codes C10  
Disease Class NameNervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O60609 BXGT004888 GDNF family receptor alpha-3 2676 reviewed
O60706 BXGT004896 ATP-binding cassette sub-family C member 9 10060 reviewed Transporter
O95180 BXGT005358 Voltage-dependent T-type calcium channel subunit alpha-1H 8912 reviewed Ion channel
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07384 BXGT006619 Calpain-1 catalytic subunit 823 reviewed Enzyme
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14060 BXGT007978 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3283 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P17655 BXGT008325 Calpain-2 catalytic subunit 824 reviewed Enzyme
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19793 BXGT008515 Retinoic acid receptor RXR-alpha 6256 reviewed Nuclear receptor
P20701 BXGT008591 Integrin alpha-L 3683 reviewed
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25105 BXGT009021 Platelet-activating factor receptor 5724 reviewed G-protein coupled receptor
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P30411 BXGT009424 B2 bradykinin receptor 624 reviewed G-protein coupled receptor
P32245 BXGT009614 Melanocortin receptor 4 4160 reviewed G-protein coupled receptor
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P41146 BXGT010226 Nociceptin receptor 4987 reviewed G-protein coupled receptor
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43487 BXGT010393 Ran-specific GTPase-activating protein 5902 reviewed Enzyme modulator
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46663 BXGT010531 B1 bradykinin receptor 623 reviewed G-protein coupled receptor
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P55210 BXGT011110 Caspase-7 840 reviewed Enzyme
P62826 BXGT011463 GTP-binding nuclear protein Ran 5901 reviewed Enzyme modulator
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q01668 BXGT012605 Voltage-dependent L-type calcium channel subunit alpha-1D 776 reviewed Ion channel
Q05586 BXGT012826 Glutamate receptor ionotropic, NMDA 1 2902 reviewed Ion channel
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q09428 BXGT013036 ATP-binding cassette sub-family C member 8 6833 reviewed Transporter
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q14654 BXGT013495 ATP-sensitive inward rectifier potassium channel 11 3767 reviewed Ion channel
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15046 BXGT013527 Lysine--tRNA ligase 3735 reviewed Enzyme
Q15842 BXGT013607 ATP-sensitive inward rectifier potassium channel 8 3764 reviewed Ion channel
Q9P0X4 BXGT021293 Voltage-dependent T-type calcium channel subunit alpha-1I 8911 reviewed Ion channel
Q9Y5N1 BXGT022297 Histamine H3 receptor 11255 reviewed G-protein coupled receptor
Q9Y5Y9 BXGT022309 Sodium channel protein type 10 subunit alpha 6336 reviewed Ion channel
Q96AE4 BXGT025980 Far upstream element-binding protein 1 8880 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease