Showing entry for Microtubule-associated protein 1B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010542
Protein NameMicrotubule-associated protein 1B
Uniport IdP46821
GeneMAP1B
Gene Id4131
DomainMAP1B_neuraxin
Pfam PF00414  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048675 axon extension
Biological Process GO:0007409 axonogenesis
Biological Process GO:0009987 cellular process
Biological Process GO:0071363 cellular response to growth factor stimulus
Biological Process GO:0071375 cellular response to peptide hormone stimulus
Biological Process GO:0016358 dendrite development
Biological Process GO:0021700 developmental maturation
Biological Process GO:0061162 establishment of monopolar cell polarity
Biological Process GO:0051915 induction of synaptic plasticity by chemical substance
Biological Process GO:0001578 microtubule bundle formation
Biological Process GO:0000226 microtubule cytoskeleton organization
Biological Process GO:0047497 mitochondrion transport along microtubule
Biological Process GO:0032387 negative regulation of intracellular transport
Biological Process GO:0007026 negative regulation of microtubule depolymerization
Biological Process GO:0001764 neuron migration
Biological Process GO:0014012 peripheral nervous system axon regeneration
Biological Process GO:0045773 positive regulation of axon extension
Biological Process GO:0031116 positive regulation of microtubule polymerization
Biological Process GO:0031114 regulation of microtubule depolymerization
Biological Process GO:0009743 response to carbohydrate
Biological Process GO:0042493 response to drug
Biological Process GO:0032355 response to estradiol
Biological Process GO:0010035 response to inorganic substance
Biological Process GO:0017085 response to insecticide
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0033189 response to vitamin A
Biological Process GO:0007416 synapse assembly
molecular function GO:0003779 actin binding
molecular function GO:0008017 microtubule binding
molecular function GO:0005543 phospholipid binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0005198 structural molecule activity
molecular function GO:0015631 tubulin binding
cellular component GO:0097440 apical dendrite
cellular component GO:0030424 axon
cellular component GO:0097441 basal dendrite
cellular component GO:0042995 cell projection
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0030426 growth cone
cellular component GO:0097457 hippocampal mossy fiber
cellular component GO:0005874 microtubule
cellular component GO:0005875 microtubule associated complex
cellular component GO:0043025 neuronal cell body
cellular component GO:0043204 perikaryon
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0001750 photoreceptor outer segment
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0036477 somatodendritic compartment
cellular component GO:0045202 synapse
cellular component GO:0043196 varicosity
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003486 BXGD000197 Aortic Aneurysm Cardiovascular Diseases
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0016952 BXGD001085 Galactosemias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0019270 BXGD001311 Hernia Pathological Conditions, Signs and Symptoms
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0034194 BXGD002472 Pyloric Stenosis Digestive System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0086437 BXGD003282 Joint laxity Musculoskeletal Diseases
C0241654 BXGD005104 Abnormal heart valve morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242852 BXGD005197 Proliferative vitreoretinopathy Eye Diseases
C0266464 BXGD005676 Polymicrogyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0268151 BXGD005838 Classical galactosemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0270824 BXGD006113 Visual seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0339543 BXGD007267 Epiretinal Membrane Eye Diseases
C0342199 BXGD007443 Iodine deficiency syndrome Endocrine System Diseases
C0423757 BXGD008504 Thin skin
C0431380 BXGD008680 Cortical Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0432072 BXGD008718 Dysmorphic features
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751495 BXGD010473 Seizures, Focal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0752308 BXGD010715 Hypoxia-Ischemia, Brain Nervous System Diseases; Cardiovascular Diseases
C0848034 BXGD010872 Low IQ
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1302995 BXGD012316 Congenital Fibrosis of the Extraocular Muscles Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C1304508 BXGD012341 Spindle cell hemangioma Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1458140 BXGD013134 Bleeding tendency Hemic and Lymphatic Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1868720 BXGD016531 Periventricular Nodular Heterotopia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4024957 BXGD021500 Proximal spinal muscular atrophy Nervous System Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0022863 n.a 420.18
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein